JP2019525955A5 - - Google Patents
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- Publication number
- JP2019525955A5 JP2019525955A5 JP2019522609A JP2019522609A JP2019525955A5 JP 2019525955 A5 JP2019525955 A5 JP 2019525955A5 JP 2019522609 A JP2019522609 A JP 2019522609A JP 2019522609 A JP2019522609 A JP 2019522609A JP 2019525955 A5 JP2019525955 A5 JP 2019525955A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- substituted
- cancer
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662361263P | 2016-07-12 | 2016-07-12 | |
| US62/361,263 | 2016-07-12 | ||
| PCT/US2017/041526 WO2018013559A1 (en) | 2016-07-12 | 2017-07-11 | Novel compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019525955A JP2019525955A (ja) | 2019-09-12 |
| JP2019525955A5 true JP2019525955A5 (https=) | 2020-08-20 |
Family
ID=60942054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522609A Pending JP2019525955A (ja) | 2016-07-12 | 2017-07-11 | 新規化合物およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9944632B2 (https=) |
| EP (1) | EP3368011A4 (https=) |
| JP (1) | JP2019525955A (https=) |
| KR (1) | KR20190039125A (https=) |
| CN (2) | CN108495618B (https=) |
| AU (1) | AU2017297344A1 (https=) |
| CA (1) | CA3030411A1 (https=) |
| HK (1) | HK1257296A1 (https=) |
| MA (1) | MA43141A (https=) |
| WO (1) | WO2018013559A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108495618B (zh) | 2016-07-12 | 2019-08-16 | 冰洲石生物科技公司 | 新的化合物及其用途 |
| US20220016102A1 (en) * | 2018-11-21 | 2022-01-20 | Shanghaitech University | Er protein regulators and use thereof |
| SG11202105256QA (en) | 2018-11-21 | 2021-06-29 | Accutar Biotechnology Inc | Novel compounds having estrogen receptor alpha degradation activity and uses thereof |
| CN113614076A (zh) * | 2019-01-03 | 2021-11-05 | 密执安大学评议会 | 雌激素受体蛋白降解剂 |
| CN112390852B (zh) * | 2019-08-14 | 2022-10-18 | 上海济煜医药科技有限公司 | 作为蛋白降解剂的化合物及其制备方法和应用 |
| EP3835298B1 (en) * | 2019-12-12 | 2024-06-26 | Accutar Biotechnology Inc. | Novel chroman derivatives having estrogen receptor degradation activity and uses thereof |
| JP2023508357A (ja) * | 2019-12-23 | 2023-03-02 | アキュター バイオテクノロジー インコーポレイテッド | エストロゲン受容体分解剤とサイクリン依存性キナーゼ阻害剤との癌治療用組み合わせ |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681835A (en) * | 1994-04-25 | 1997-10-28 | Glaxo Wellcome Inc. | Non-steroidal ligands for the estrogen receptor |
| JP5934986B2 (ja) * | 2011-09-07 | 2016-06-15 | 公益財団法人ヒューマンサイエンス振興財団 | アポトーシス阻害タンパク質リガンド−エストロゲン受容体リガンドハイブリッド化合物並びにそれを利用したエストロゲン受容体分解誘導剤及び乳癌、子宮頚癌又は卵巣癌の予防及び治療剤 |
| KR102668696B1 (ko) * | 2012-01-12 | 2024-05-29 | 예일 유니버시티 | E3 유비퀴틴 리가아제에 의한 표적 단백질 및 다른 폴리펩티드의 증진된 분해를 위한 화합물 및 방법 |
| WO2014008159A1 (en) * | 2012-07-03 | 2014-01-09 | The University Of North Carolina At Chapel Hill | Selective estrogen receptor degraders for treatment of tamoxifen resistant tumors |
| US9896466B2 (en) * | 2013-04-24 | 2018-02-20 | Kkcg Ag | Tamoxifen derivatives for treatment of neoplastic diseases, especially with high HER2 protein level |
| GB201311891D0 (en) * | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| CN108495618B (zh) * | 2016-07-12 | 2019-08-16 | 冰洲石生物科技公司 | 新的化合物及其用途 |
-
2017
- 2017-07-11 CN CN201780001677.9A patent/CN108495618B/zh not_active Expired - Fee Related
- 2017-07-11 MA MA043141A patent/MA43141A/fr unknown
- 2017-07-11 CA CA3030411A patent/CA3030411A1/en not_active Abandoned
- 2017-07-11 WO PCT/US2017/041526 patent/WO2018013559A1/en not_active Ceased
- 2017-07-11 KR KR1020197003884A patent/KR20190039125A/ko not_active Ceased
- 2017-07-11 US US15/646,793 patent/US9944632B2/en active Active
- 2017-07-11 EP EP17828300.8A patent/EP3368011A4/en not_active Withdrawn
- 2017-07-11 AU AU2017297344A patent/AU2017297344A1/en not_active Abandoned
- 2017-07-11 CN CN201910655485.0A patent/CN110294788A/zh active Pending
- 2017-07-11 JP JP2019522609A patent/JP2019525955A/ja active Pending
- 2017-07-11 HK HK18116445.7A patent/HK1257296A1/zh unknown
-
2018
- 2018-01-30 US US15/883,495 patent/US10450307B2/en not_active Expired - Fee Related
-
2019
- 2019-09-04 US US16/560,178 patent/US10968212B2/en not_active Expired - Fee Related
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