JP2019524889A5 - - Google Patents
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- JP2019524889A5 JP2019524889A5 JP2019530368A JP2019530368A JP2019524889A5 JP 2019524889 A5 JP2019524889 A5 JP 2019524889A5 JP 2019530368 A JP2019530368 A JP 2019530368A JP 2019530368 A JP2019530368 A JP 2019530368A JP 2019524889 A5 JP2019524889 A5 JP 2019524889A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- subject
- composition according
- effective amount
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims description 35
- 150000001875 compounds Chemical class 0.000 claims description 16
- 239000000651 prodrug Substances 0.000 claims description 10
- 229940002612 prodrug Drugs 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 208000001132 Osteoporosis Diseases 0.000 claims description 4
- 210000001789 adipocyte Anatomy 0.000 claims description 4
- 210000000577 adipose tissue Anatomy 0.000 claims description 4
- 208000024891 symptom Diseases 0.000 claims description 4
- 102000011690 Adiponectin Human genes 0.000 claims description 3
- 108010076365 Adiponectin Proteins 0.000 claims description 3
- 206010065687 Bone loss Diseases 0.000 claims description 3
- 210000000963 osteoblast Anatomy 0.000 claims description 3
- SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical class [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 claims description 2
- 210000000988 bone and bone Anatomy 0.000 claims description 2
- 230000008468 bone growth Effects 0.000 claims description 2
- 230000003442 weekly effect Effects 0.000 claims description 2
- 230000002354 daily effect Effects 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 1
- 230000003203 everyday effect Effects 0.000 claims 1
- 230000001582 osteoblastic effect Effects 0.000 claims 1
- 208000029725 Metabolic bone disease Diseases 0.000 description 1
- 206010049088 Osteopenia Diseases 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022090843A JP2022116294A (ja) | 2016-08-18 | 2022-06-03 | 骨疾患の治療のためのＰＰＡＲγアゴニスト |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662376732P | 2016-08-18 | 2016-08-18 | |
| US62/376,732 | 2016-08-18 | ||
| PCT/US2017/047584 WO2018035449A1 (en) | 2016-08-18 | 2017-08-18 | Pparϒ agonist for treatment of bone disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022090843A Division JP2022116294A (ja) | 2016-08-18 | 2022-06-03 | 骨疾患の治療のためのＰＰＡＲγアゴニスト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019524889A JP2019524889A (ja) | 2019-09-05 |
| JP2019524889A5 true JP2019524889A5 (https=) | 2020-10-01 |
Family
ID=61197122
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019530368A Pending JP2019524889A (ja) | 2016-08-18 | 2017-08-18 | 骨疾患の治療のためのＰＰＡＲγアゴニスト |
| JP2022090843A Withdrawn JP2022116294A (ja) | 2016-08-18 | 2022-06-03 | 骨疾患の治療のためのＰＰＡＲγアゴニスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022090843A Withdrawn JP2022116294A (ja) | 2016-08-18 | 2022-06-03 | 骨疾患の治療のためのＰＰＡＲγアゴニスト |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190167660A1 (https=) |
| EP (1) | EP3500269A4 (https=) |
| JP (2) | JP2019524889A (https=) |
| KR (1) | KR20190065252A (https=) |
| CN (1) | CN109843292A (https=) |
| AU (1) | AU2017313842A1 (https=) |
| BR (1) | BR112019003133A2 (https=) |
| CA (1) | CA3033971A1 (https=) |
| EA (1) | EA201990513A1 (https=) |
| SG (2) | SG10202101500WA (https=) |
| WO (1) | WO2018035449A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201791982A1 (ru) | 2015-03-09 | 2020-02-17 | Интекрин Терапьютикс, Инк. | Способы лечения неалкогольной жировой болезни печени и/или липодистрофии |
| AU2018249822A1 (en) | 2017-04-03 | 2019-10-31 | Coherus Biosciences Inc. | PPArgamma agonist for treatment of progressive supranuclear palsy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001083427A1 (en) * | 2000-04-28 | 2001-11-08 | Sankyo Company, Limited | PPARη MODULATORS |
| US7223761B2 (en) * | 2003-10-03 | 2007-05-29 | Amgen Inc. | Salts and polymorphs of a potent antidiabetic compound |
| US20050250820A1 (en) * | 2004-03-08 | 2005-11-10 | Amgen Inc. | Therapeutic modulation of PPARgamma activity |
| KR102056756B1 (ko) * | 2013-01-30 | 2019-12-17 | 인테크린 테라퓨틱스, 아이엔씨. | 다발성 경화증의 치료를 위한 PPARγ 작용제 |
| ES2785317T3 (es) * | 2014-10-10 | 2020-10-06 | Liminal Biosciences Ltd | Compuestos aromáticos sustituidos y composiciones farmacéuticas para la prevención y el tratamiento de la osteoporosis |
-
2017
- 2017-08-18 AU AU2017313842A patent/AU2017313842A1/en not_active Abandoned
- 2017-08-18 SG SG10202101500WA patent/SG10202101500WA/en unknown
- 2017-08-18 CA CA3033971A patent/CA3033971A1/en active Pending
- 2017-08-18 BR BR112019003133-2A patent/BR112019003133A2/pt not_active IP Right Cessation
- 2017-08-18 WO PCT/US2017/047584 patent/WO2018035449A1/en not_active Ceased
- 2017-08-18 SG SG11201901328VA patent/SG11201901328VA/en unknown
- 2017-08-18 CN CN201780063392.8A patent/CN109843292A/zh active Pending
- 2017-08-18 EA EA201990513A patent/EA201990513A1/ru unknown
- 2017-08-18 US US16/326,070 patent/US20190167660A1/en not_active Abandoned
- 2017-08-18 KR KR1020197007605A patent/KR20190065252A/ko not_active Ceased
- 2017-08-18 JP JP2019530368A patent/JP2019524889A/ja active Pending
- 2017-08-18 EP EP17842205.1A patent/EP3500269A4/en not_active Withdrawn
-
2022
- 2022-06-03 JP JP2022090843A patent/JP2022116294A/ja not_active Withdrawn
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