JP2019523630A5 - - Google Patents
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- JP2019523630A5 JP2019523630A5 JP2018555198A JP2018555198A JP2019523630A5 JP 2019523630 A5 JP2019523630 A5 JP 2019523630A5 JP 2018555198 A JP2018555198 A JP 2018555198A JP 2018555198 A JP2018555198 A JP 2018555198A JP 2019523630 A5 JP2019523630 A5 JP 2019523630A5
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 34
- 229920001184 polypeptide Polymers 0.000 claims 32
- 102000004196 processed proteins & peptides Human genes 0.000 claims 32
- 206010028980 Neoplasm Diseases 0.000 claims 15
- 239000000427 antigen Substances 0.000 claims 13
- 108091007433 antigens Proteins 0.000 claims 13
- 102000036639 antigens Human genes 0.000 claims 13
- 239000003814 drug Substances 0.000 claims 7
- 235000001014 amino acid Nutrition 0.000 claims 6
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- 208000014829 head and neck neoplasm Diseases 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 6
- 210000004881 tumor cell Anatomy 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 5
- 229940124597 therapeutic agent Drugs 0.000 claims 5
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 4
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- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 claims 1
- 108010055196 EphA2 Receptor Proteins 0.000 claims 1
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- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 1
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- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 1
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- 102100033579 Trophoblast glycoprotein Human genes 0.000 claims 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 claims 1
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021192091A JP2022058338A (ja) | 2016-04-22 | 2021-11-26 | Ｃｄ１３７に対する新規の二重特異性ポリペプチド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201607046 | 2016-04-22 | ||
| GB1607046.8 | 2016-04-22 | ||
| PCT/EP2017/059656 WO2017182672A1 (en) | 2016-04-22 | 2017-04-24 | Novel bispecific polypeptides against cd137 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021192091A Division JP2022058338A (ja) | 2016-04-22 | 2021-11-26 | Ｃｄ１３７に対する新規の二重特異性ポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019523630A JP2019523630A (ja) | 2019-08-29 |
| JP2019523630A5 true JP2019523630A5 (https=) | 2020-05-21 |
Family
ID=58609424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555198A Pending JP2019523630A (ja) | 2016-04-22 | 2017-04-24 | Ｃｄ１３７に対する新規の二重特異性ポリペプチド |
| JP2021192091A Pending JP2022058338A (ja) | 2016-04-22 | 2021-11-26 | Ｃｄ１３７に対する新規の二重特異性ポリペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021192091A Pending JP2022058338A (ja) | 2016-04-22 | 2021-11-26 | Ｃｄ１３７に対する新規の二重特異性ポリペプチド |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20190169308A1 (https=) |
| EP (1) | EP3445788B1 (https=) |
| JP (2) | JP2019523630A (https=) |
| KR (1) | KR102426765B1 (https=) |
| CN (1) | CN109195994A (https=) |
| AU (1) | AU2017252233A1 (https=) |
| BR (1) | BR112018071612A2 (https=) |
| CA (1) | CA3021618A1 (https=) |
| DK (1) | DK3445788T3 (https=) |
| ES (1) | ES2910365T3 (https=) |
| IL (1) | IL262482A (https=) |
| MX (1) | MX2018012897A (https=) |
| RU (1) | RU2018139339A (https=) |
| WO (1) | WO2017182672A1 (https=) |
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| JP6882978B2 (ja) | 2014-10-29 | 2021-06-02 | バイスクルアールディー・リミテッド | Ｍｔ１−ｍｍｐに特異的な二環性ペプチドリガンド |
| BR112018074453A2 (pt) | 2016-05-27 | 2019-03-19 | Abbvie Biotherapeutics Inc. | proteínas de ligação biespecíficas ligando uma protéina imunomoduladora e um antígeno tumoral |
| KR102664891B1 (ko) | 2016-06-20 | 2024-05-13 | 에프-스타 테라퓨틱스 리미티드 | Pd-l1 및 lag-3에 결합하는 결합 분자 |
| KR20190022632A (ko) | 2016-06-20 | 2019-03-06 | 에프-스타 베타 리미티드 | Lag-3 결합 구성원 |
| SG11201811431VA (en) | 2016-07-14 | 2019-01-30 | Genmab As | Multispecific antibodies against cd40 and cd137 |
| GB201612520D0 (en) | 2016-07-19 | 2016-08-31 | F-Star Beta Ltd | Binding molecules |
| BR112019005895A2 (pt) | 2016-09-23 | 2019-06-11 | Merus N.V. | moléculas de ligação que modulam uma atividade biológica expressa por uma célula |
| AU2018250641B2 (en) | 2017-04-11 | 2025-03-13 | Inhibrx Biosciences, Inc. | Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same |
| JP7297672B2 (ja) | 2017-04-13 | 2023-06-26 | アジェナス インコーポレイテッド | 抗ｃｄ１３７抗体およびその使用方法 |
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| WO2019092452A1 (en) * | 2017-11-13 | 2019-05-16 | Crescendo Biologics Limited | Molecules that bind to cd137 and psma |
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| SG11202008399QA (en) | 2018-03-12 | 2020-09-29 | Genmab As | Antibodies |
| JP7551500B2 (ja) * | 2018-04-04 | 2024-09-17 | バイスクルテクス・リミテッド | ヘテロタンデム二環式ペプチド複合体 |
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| US12168691B2 (en) | 2018-05-31 | 2024-12-17 | Board Of Regents, The University Of Texas System | VHS format bi-specific antibodies specific for HER2 and VEGF and use thereof |
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| BR112021000282A2 (pt) | 2018-07-12 | 2021-04-06 | F-Star Beta Limited | Moléculas de anticorpo que se ligam a cd137 e ox40 |
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| CN112996809A (zh) * | 2018-10-10 | 2021-06-18 | 酵活有限公司 | 结合4-1bb和肿瘤相关抗原的抗体构建体以及其用途 |
| WO2020076992A1 (en) * | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | 5t4 single domain antibodies and therapeutic compositions thereof |
| CN112638950B (zh) * | 2018-10-22 | 2024-09-06 | 南通壹宸生物医药科技有限公司 | 一种双特异性抗体 |
| CN113286825B (zh) * | 2018-11-30 | 2024-06-18 | 爱必乐生物公司 | 抗pd-l1/抗4-1bb双特异性抗体及其用途 |
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-
2017
- 2017-04-24 AU AU2017252233A patent/AU2017252233A1/en not_active Abandoned
- 2017-04-24 RU RU2018139339A patent/RU2018139339A/ru unknown
- 2017-04-24 DK DK17718928.9T patent/DK3445788T3/da active
- 2017-04-24 CA CA3021618A patent/CA3021618A1/en active Pending
- 2017-04-24 EP EP17718928.9A patent/EP3445788B1/en active Active
- 2017-04-24 BR BR112018071612-0A patent/BR112018071612A2/pt not_active IP Right Cessation
- 2017-04-24 ES ES17718928T patent/ES2910365T3/es active Active
- 2017-04-24 US US16/094,127 patent/US20190169308A1/en not_active Abandoned
- 2017-04-24 WO PCT/EP2017/059656 patent/WO2017182672A1/en not_active Ceased
- 2017-04-24 MX MX2018012897A patent/MX2018012897A/es unknown
- 2017-04-24 JP JP2018555198A patent/JP2019523630A/ja active Pending
- 2017-04-24 CN CN201780025116.2A patent/CN109195994A/zh active Pending
- 2017-04-24 KR KR1020187030680A patent/KR102426765B1/ko active Active
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2018
- 2018-10-21 IL IL262482A patent/IL262482A/en unknown
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2021
- 2021-09-23 US US17/482,708 patent/US12173082B2/en active Active
- 2021-11-26 JP JP2021192091A patent/JP2022058338A/ja active Pending
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