JP2019518724A5 - - Google Patents
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- Publication number
- JP2019518724A5 JP2019518724A5 JP2018555889A JP2018555889A JP2019518724A5 JP 2019518724 A5 JP2019518724 A5 JP 2019518724A5 JP 2018555889 A JP2018555889 A JP 2018555889A JP 2018555889 A JP2018555889 A JP 2018555889A JP 2019518724 A5 JP2019518724 A5 JP 2019518724A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- il4i1
- infection
- respiratory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 14
- 101001121408 Homo sapiens L-amino-acid oxidase Proteins 0.000 claims 10
- 102100026388 L-amino-acid oxidase Human genes 0.000 claims 9
- 239000005557 antagonist Substances 0.000 claims 6
- 206010057190 Respiratory tract infections Diseases 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 4
- 208000023504 respiratory system disease Diseases 0.000 claims 4
- 208000035143 Bacterial infection Diseases 0.000 claims 3
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 3
- 208000022362 bacterial infectious disease Diseases 0.000 claims 3
- 208000036142 Viral infection Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 230000009385 viral infection Effects 0.000 claims 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010014561 Emphysema Diseases 0.000 claims 1
- 241000606768 Haemophilus influenzae Species 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 241000588655 Moraxella catarrhalis Species 0.000 claims 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 claims 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 claims 1
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 claims 1
- -1 antibody conjugate Proteins 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 201000009267 bronchiectasis Diseases 0.000 claims 1
- 206010006451 bronchitis Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229940047650 haemophilus influenzae Drugs 0.000 claims 1
- 102000056209 human IL4I1 Human genes 0.000 claims 1
- 229940127121 immunoconjugate Drugs 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 239000008024 pharmaceutical diluent Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940076372 protein antagonist Drugs 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662327718P | 2016-04-26 | 2016-04-26 | |
| US62/327,718 | 2016-04-26 | ||
| PCT/US2017/028806 WO2017189353A1 (en) | 2016-04-26 | 2017-04-21 | Treating respiratory diseases by targeting interleukin 4 induced 1 (il4i1) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019518724A JP2019518724A (ja) | 2019-07-04 |
| JP2019518724A5 true JP2019518724A5 (enExample) | 2020-06-11 |
Family
ID=58664849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555889A Pending JP2019518724A (ja) | 2016-04-26 | 2017-04-21 | インターロイキン４誘導１（ｉｌ４ｉ１）の標的化による呼吸器疾患の治療 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20190135911A1 (enExample) |
| EP (1) | EP3448413A1 (enExample) |
| JP (1) | JP2019518724A (enExample) |
| WO (1) | WO2017189353A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3721894A1 (en) * | 2019-04-10 | 2020-10-14 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Interleukin-4-induced gene 1 (il4i1) as a biomarker and uses thereof |
| CN115785277B (zh) * | 2022-09-09 | 2023-06-20 | 上海百英生物科技股份有限公司 | 一种抗IL4i1纳米抗体的制备及其应用 |
| WO2025231449A1 (en) * | 2024-05-02 | 2025-11-06 | Institute For Myeloma & Bone Cancer Research | Prediction, diagnosis, and treatment of multiple myeloma |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US7635754B2 (en) * | 2004-09-22 | 2009-12-22 | Aerovance, Inc. | Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same |
| EP2414520A2 (en) * | 2009-03-31 | 2012-02-08 | Altair Therapeutics, Inc. | Methods of modulating an immune response to a viral infection |
-
2017
- 2017-04-21 JP JP2018555889A patent/JP2019518724A/ja active Pending
- 2017-04-21 WO PCT/US2017/028806 patent/WO2017189353A1/en not_active Ceased
- 2017-04-21 EP EP17720987.1A patent/EP3448413A1/en not_active Withdrawn
- 2017-04-21 US US16/096,699 patent/US20190135911A1/en not_active Abandoned
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