JP2019518443A5 - - Google Patents
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- Publication number
- JP2019518443A5 JP2019518443A5 JP2018559754A JP2018559754A JP2019518443A5 JP 2019518443 A5 JP2019518443 A5 JP 2019518443A5 JP 2018559754 A JP2018559754 A JP 2018559754A JP 2018559754 A JP2018559754 A JP 2018559754A JP 2019518443 A5 JP2019518443 A5 JP 2019518443A5
- Authority
- JP
- Japan
- Prior art keywords
- microvilli
- pgla
- pdms
- immunofluorescence
- mimic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PJRSUKFWFKUDTH-JWDJOUOUSA-N (2s)-6-amino-2-[[2-[[(2s)-2-[[(2s,3s)-2-[[(2s)-2-[[2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-[(2-aminoacetyl)amino]-4-methylsulfanylbutanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]propanoyl]amino]acetyl]amino]propanoyl Chemical compound CSCC[C@H](NC(=O)CN)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O PJRSUKFWFKUDTH-JWDJOUOUSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 210000000110 microvilli Anatomy 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 108010021753 peptide-Gly-Leu-amide Proteins 0.000 description 1
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR16/54213 | 2016-05-11 | ||
| FR1654213A FR3051195B1 (fr) | 2016-05-11 | 2016-05-11 | Puce de co-culture cellulaire et son procede de fabrication |
| PCT/FR2017/051148 WO2017194894A1 (fr) | 2016-05-11 | 2017-05-11 | Puce de co-culture cellulaire et son procede de fabrication |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019518443A JP2019518443A (ja) | 2019-07-04 |
| JP2019518443A5 true JP2019518443A5 (enExample) | 2020-06-18 |
| JP6983180B2 JP6983180B2 (ja) | 2021-12-17 |
Family
ID=56855554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559754A Active JP6983180B2 (ja) | 2016-05-11 | 2017-05-11 | 細胞共培養チップ及びその製造に関するプロセス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11857958B2 (enExample) |
| EP (1) | EP3455342B1 (enExample) |
| JP (1) | JP6983180B2 (enExample) |
| CN (1) | CN109699180B (enExample) |
| FR (1) | FR3051195B1 (enExample) |
| WO (1) | WO2017194894A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230098968A1 (en) * | 2018-05-25 | 2023-03-30 | The University Of North Carolina At Chapel Hill | Formation of arrays of planar intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone |
| JP2022511375A (ja) | 2018-11-16 | 2022-01-31 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | インビトロ細胞培養粘液系 |
| CN113820189A (zh) * | 2021-09-10 | 2021-12-21 | 深圳市森盈生物科技有限公司 | 一种用于非妇科的肿瘤筛查的细胞芯片的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004065087A (ja) * | 2002-08-06 | 2004-03-04 | National Institute For Materials Science | 高密度培養が可能な細胞培養体とその培養モジュール |
| US7494811B2 (en) * | 2003-05-01 | 2009-02-24 | Lifenet Health | In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby |
| JP2005143343A (ja) | 2003-11-12 | 2005-06-09 | Jgc Corp | 細胞培養装置および細胞培養方法 |
| DK2138233T3 (da) * | 2008-06-02 | 2011-01-31 | Boehringer Ingelheim Micropart | Mikrofluid foliestruktur til dosering af væsker |
| KR102140055B1 (ko) | 2008-07-16 | 2020-07-31 | 칠드런'즈 메디컬 센터 코포레이션 | 마이크로채널을 갖는 기관 모방 장치 및 그 사용 및 제조 방법 |
| JP2012509663A (ja) * | 2008-11-21 | 2012-04-26 | コーニング インコーポレイテッド | 細胞培養のための、突起間隔を開けた基板および装置 |
| US8748180B2 (en) * | 2009-07-29 | 2014-06-10 | Cornell University | Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof |
| FR2955852B1 (fr) * | 2010-01-29 | 2015-09-18 | Corning Inc | Dispositif microfluideique en verre, ceramique ou vitroceramique, comprenant une couche intermediaire de traitement comprenant au moins une face ayant une surface structuree ouverte definissant un microcanal ferme par une couche formant feuille en verre, ceramique ou vitroceramique essentiellement plane |
| JP5700460B2 (ja) | 2010-09-10 | 2015-04-15 | 株式会社島津製作所 | 細胞培養デバイス及び細胞培養方法 |
| CA2828110C (en) * | 2011-02-28 | 2020-03-31 | President And Fellows Of Harvard College | Cell culture system |
| WO2014008358A1 (en) * | 2012-07-05 | 2014-01-09 | Cornell University | Porous membrane apparatus, method, and applications |
| CN104830683B (zh) * | 2015-04-30 | 2017-06-30 | 大连医科大学附属第二医院 | 一种用于模拟体内肿瘤细胞及其转移微环境的仿生微流控芯片 |
-
2016
- 2016-05-11 FR FR1654213A patent/FR3051195B1/fr active Active
-
2017
- 2017-05-11 WO PCT/FR2017/051148 patent/WO2017194894A1/fr not_active Ceased
- 2017-05-11 US US16/300,504 patent/US11857958B2/en active Active
- 2017-05-11 JP JP2018559754A patent/JP6983180B2/ja active Active
- 2017-05-11 EP EP17727301.8A patent/EP3455342B1/fr active Active
- 2017-05-11 CN CN201780043057.1A patent/CN109699180B/zh active Active
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