JP2019515011A5 - - Google Patents
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- Publication number
- JP2019515011A5 JP2019515011A5 JP2018559831A JP2018559831A JP2019515011A5 JP 2019515011 A5 JP2019515011 A5 JP 2019515011A5 JP 2018559831 A JP2018559831 A JP 2018559831A JP 2018559831 A JP2018559831 A JP 2018559831A JP 2019515011 A5 JP2019515011 A5 JP 2019515011A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hepatic artery
- pressure
- reduced
- liver tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002767 hepatic artery Anatomy 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 22
- 210000005228 liver tissue Anatomy 0.000 claims description 20
- 239000003795 chemical substances by application Substances 0.000 claims description 19
- 206010021143 Hypoxia Diseases 0.000 claims description 17
- 230000007954 hypoxia Effects 0.000 claims description 17
- 230000001370 bioreducing effect Effects 0.000 claims description 13
- QVMPZNRFXAKISM-UHFFFAOYSA-N tirapazamine Chemical group C1=CC=C2[N+]([O-])=NC(=N)N(O)C2=C1 QVMPZNRFXAKISM-UHFFFAOYSA-N 0.000 claims description 6
- 229950002376 tirapazamine Drugs 0.000 claims description 6
- 230000004872 arterial blood pressure Effects 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 206010053648 Vascular occlusion Diseases 0.000 claims description 2
- 239000011324 bead Substances 0.000 claims description 2
- 230000017531 blood circulation Effects 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- 230000003073 embolic effect Effects 0.000 claims description 2
- 125000004494 ethyl ester group Chemical group 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 239000010491 poppyseed oil Substances 0.000 claims description 2
- 208000021331 vascular occlusion disease Diseases 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 25
- 210000004185 liver Anatomy 0.000 claims 1
- 239000004005 microsphere Substances 0.000 claims 1
- 238000010348 incorporation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662336498P | 2016-05-13 | 2016-05-13 | |
| US62/336,498 | 2016-05-13 | ||
| PCT/US2017/032524 WO2017197342A1 (en) | 2016-05-13 | 2017-05-12 | Methods for treating liver tissue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019515011A JP2019515011A (ja) | 2019-06-06 |
| JP2019515011A5 true JP2019515011A5 (enExample) | 2020-06-18 |
Family
ID=60266797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559831A Pending JP2019515011A (ja) | 2016-05-13 | 2017-05-12 | 肝臓組織を処置するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20190083501A1 (enExample) |
| EP (1) | EP3454833B1 (enExample) |
| JP (1) | JP2019515011A (enExample) |
| KR (1) | KR20190007017A (enExample) |
| CN (1) | CN108348463A (enExample) |
| ES (1) | ES2952157T3 (enExample) |
| WO (1) | WO2017197342A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019030312A1 (en) * | 2017-08-10 | 2019-02-14 | Katholieke Universiteit Leuven | APPARATUS FOR MEASURING PRESSURE VARIATIONS IN STOMACH |
| RU2706373C1 (ru) * | 2019-03-01 | 2019-11-18 | Федеральное Государственное бюджетное образовательное учреждение высшего образования Дагестанский государственный медицинский университет Министерства здравоохранения Российской Федерации | Способ определения локализации опухолевой обструкции билиарного тракта и степени её распространенности |
| CA3213123A1 (en) * | 2021-03-25 | 2022-09-29 | Robert L. Kruse | Hydrodynamic gene delivery |
| CN113730694B (zh) * | 2021-09-18 | 2024-05-14 | 南昌大学第二附属医院 | 一种腹膜透析管 |
| CN114209871B (zh) * | 2021-10-29 | 2022-12-06 | 厦门大学 | 一种化疗药物纳米颗粒-碘油超稳定均相化栓塞剂的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009126705A2 (en) * | 2008-04-10 | 2009-10-15 | Virginia Commonwealth University | Induction of tumor hypoxia for cancer therapy |
| JP5765634B2 (ja) * | 2008-10-21 | 2015-08-19 | スレッシュホールド ファーマシューティカルズ， インコーポレイテッド | 低酸素活性化型プロドラッグを用いるがんの処置 |
| WO2014182959A2 (en) * | 2013-05-08 | 2014-11-13 | Embolx, Inc. | Device and methods for transvascular tumor embolization with integrated flow regulation |
-
2017
- 2017-05-12 ES ES17796990T patent/ES2952157T3/es active Active
- 2017-05-12 KR KR1020187035908A patent/KR20190007017A/ko not_active Ceased
- 2017-05-12 JP JP2018559831A patent/JP2019515011A/ja active Pending
- 2017-05-12 EP EP17796990.4A patent/EP3454833B1/en active Active
- 2017-05-12 CN CN201780003986.XA patent/CN108348463A/zh active Pending
- 2017-05-12 WO PCT/US2017/032524 patent/WO2017197342A1/en not_active Ceased
-
2018
- 2018-11-09 US US16/186,073 patent/US20190083501A1/en not_active Abandoned
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