JP2019512464A5 - - Google Patents
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- JP2019512464A5 JP2019512464A5 JP2018543153A JP2018543153A JP2019512464A5 JP 2019512464 A5 JP2019512464 A5 JP 2019512464A5 JP 2018543153 A JP2018543153 A JP 2018543153A JP 2018543153 A JP2018543153 A JP 2018543153A JP 2019512464 A5 JP2019512464 A5 JP 2019512464A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- chain variable
- variable region
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022030779A JP2022069488A (ja) | 2016-02-17 | 2022-03-01 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2023216464A JP2024019677A (ja) | 2016-02-17 | 2023-12-22 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662296594P | 2016-02-17 | 2016-02-17 | |
| US62/296,594 | 2016-02-17 | ||
| US201662396084P | 2016-09-16 | 2016-09-16 | |
| US62/396,084 | 2016-09-16 | ||
| PCT/US2017/018177 WO2017143069A1 (en) | 2016-02-17 | 2017-02-16 | Bcma antibodies and use of same to treat cancer and immunological disorders |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020024261A Division JP2020073605A (ja) | 2016-02-17 | 2020-02-17 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2022030779A Division JP2022069488A (ja) | 2016-02-17 | 2022-03-01 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019512464A JP2019512464A (ja) | 2019-05-16 |
| JP2019512464A5 true JP2019512464A5 (enExample) | 2020-03-26 |
| JP7152309B2 JP7152309B2 (ja) | 2022-10-12 |
Family
ID=59562012
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543153A Active JP7152309B2 (ja) | 2016-02-17 | 2017-02-16 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2020024261A Pending JP2020073605A (ja) | 2016-02-17 | 2020-02-17 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2022030779A Withdrawn JP2022069488A (ja) | 2016-02-17 | 2022-03-01 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2023216464A Pending JP2024019677A (ja) | 2016-02-17 | 2023-12-22 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020024261A Pending JP2020073605A (ja) | 2016-02-17 | 2020-02-17 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2022030779A Withdrawn JP2022069488A (ja) | 2016-02-17 | 2022-03-01 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
| JP2023216464A Pending JP2024019677A (ja) | 2016-02-17 | 2023-12-22 | 癌及び免疫学的障害を治療するためのｂｃｍａ抗生物質及びその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US20190194338A1 (enExample) |
| EP (1) | EP3416687A4 (enExample) |
| JP (4) | JP7152309B2 (enExample) |
| KR (1) | KR102816905B1 (enExample) |
| CN (2) | CN116063503A (enExample) |
| AU (2) | AU2017219747B2 (enExample) |
| BR (1) | BR112018016697A2 (enExample) |
| CA (1) | CA3011900A1 (enExample) |
| HK (1) | HK1259075A1 (enExample) |
| IL (2) | IL311107A (enExample) |
| MA (1) | MA44254A (enExample) |
| MX (2) | MX2018009700A (enExample) |
| SG (2) | SG10202007836WA (enExample) |
| WO (1) | WO2017143069A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL311107A (en) | 2016-02-17 | 2024-04-01 | Seagen Inc | BCMA antibodies and their use for the treatment of cancer and immune disorders |
| BR112019023608A2 (pt) | 2017-05-12 | 2020-05-26 | Crispr Therapeutics Ag | Materiais e métodos para células manipuladas e seus usos em imuno-oncologia |
| US11166985B2 (en) | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| EP3790629A1 (en) | 2018-05-11 | 2021-03-17 | CRISPR Therapeutics AG | Methods and compositions for treating cancer |
| CA3100187A1 (en) * | 2018-06-26 | 2020-01-02 | Abl Bio, Inc. | Anti-bcma antibody and use thereof |
| MX2021000532A (es) | 2018-07-19 | 2021-04-12 | Regeneron Pharma | Receptores antigénicos quiméricos con especificidad para bcma y usos de estos. |
| TWI838389B (zh) | 2018-07-19 | 2024-04-11 | 美商再生元醫藥公司 | 雙特異性抗-BCMAｘ抗-CD3抗體及其用途 |
| WO2020088631A1 (en) | 2018-11-01 | 2020-05-07 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for t cell engineering |
| SG11202106481SA (en) * | 2018-12-19 | 2021-07-29 | Seagen Inc | Controlled fucosylation of antibodies |
| JP7554759B2 (ja) * | 2019-02-26 | 2024-09-20 | ソレント・セラピューティクス・インコーポレイテッド | Ｂｃｍａに結合する抗原結合性タンパク質 |
| SG11202109002XA (en) | 2019-03-21 | 2021-09-29 | Regeneron Pharma | Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy |
| AU2020267057A1 (en) | 2019-04-30 | 2021-11-18 | Crispr Therapeutics Ag | Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19 |
| DK3967329T3 (da) | 2019-05-07 | 2026-05-11 | Gracell Bioscience Shanghai Co Ltd | Genmanipuleret immuncelle, der er målrettet mod bcma, og anvendelse deraf |
| US20220218835A1 (en) * | 2019-05-31 | 2022-07-14 | Medimmune, Llc | Combination therapy |
| BR112022001546A2 (pt) * | 2019-07-30 | 2022-03-22 | Jiangsu Hansoh Pharmaceutical Group Co Ltd | Anticorpo anti-bcma, fragmento de ligação ao antígeno do mesmo e uso médico do mesmo |
| CN112409482B (zh) * | 2019-08-20 | 2022-08-26 | 杭州尚健生物技术有限公司 | Bcma抗体 |
| EP4023673A4 (en) * | 2019-10-10 | 2023-03-15 | Suzhou Qin Pharmaceuticals Co., Ltd. | ANTI-BCMA HUMANIZED MONOCLONAL ANTIBODY WITH HUMAN-MONKEY CROSS-REACTIVITY |
| WO2021136308A1 (en) * | 2020-01-03 | 2021-07-08 | Biosion Inc. | Antibodies binding bcma and uses thereof |
| CN113248611B (zh) * | 2020-02-13 | 2026-02-06 | 上海泰槿生物技术有限公司 | 抗bcma抗体、其药物组合物及应用 |
| AU2021244215A1 (en) | 2020-03-26 | 2022-10-13 | Seagen Inc. | Methods of treating multiple myeloma |
| CN115279781B (zh) * | 2020-03-26 | 2025-05-09 | 上海翰森生物医药科技有限公司 | 抗体药物偶联物及其医药用途 |
| BR112022020332A2 (pt) | 2020-04-10 | 2022-12-13 | Seagen Inc | Composto conjugado anticorpo-droga, composição, método de tratamento de câncer e de um distúrbio autoimune |
| JP2023548538A (ja) | 2020-11-08 | 2023-11-17 | シージェン インコーポレイテッド | 併用療法 |
| CA3213636A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| MX2023012364A (es) | 2021-04-20 | 2023-11-01 | Seagen Inc | Modulacion de citotoxicidad celular dependiente de anticuerpos. |
| IL308795A (en) | 2021-05-28 | 2024-01-01 | Seagen Inc | Anthracycline antibody conjugates |
| CA3228311A1 (en) | 2021-08-12 | 2023-02-16 | Ke HE | Bispecific recombinant protein and use thereof |
| WO2023019398A1 (en) * | 2021-08-16 | 2023-02-23 | Utc Therapeutics (Shanghai) Co., Ltd. | Bcma targetting antibodies, chimeric antigen receptors, and uses thereof |
| TW202327650A (zh) | 2021-09-23 | 2023-07-16 | 美商思進公司 | 治療多發性骨髓瘤之方法 |
| US20250130233A1 (en) * | 2021-10-27 | 2025-04-24 | Janssen Biotech, Inc. | Methods for enhanced bcma immunohistochemistry detection in human and monkey tissue |
| CN116333134A (zh) * | 2021-12-22 | 2023-06-27 | 上海君实生物医药科技股份有限公司 | 抗bcma抗体及其用途 |
| IL315508A (en) | 2022-03-17 | 2024-11-01 | Seagen Inc | Camptothecin conjugates |
| WO2024129756A1 (en) | 2022-12-13 | 2024-06-20 | Seagen Inc. | Site-specific engineered cysteine antibody drug conjugates |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| CN119548619A (zh) * | 2023-08-10 | 2025-03-04 | 亘喜生物科技（上海）有限公司 | 一种双靶点car-t细胞在治疗系统性红斑狼疮及其他b细胞自身免疫病中的用途 |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| IL327045A (en) | 2023-10-05 | 2026-05-01 | Capstan Therapeutics Inc | Structure-restricted ionizable cationic lipids and lipid nanoparticles |
| WO2025090774A1 (en) | 2023-10-24 | 2025-05-01 | Seagen Inc. | Chemotherapeutic compounds and methods of use |
| WO2025149947A1 (en) | 2024-01-12 | 2025-07-17 | Seagen Inc. | Antibody-drug conjugates |
| US20250242056A1 (en) | 2024-01-26 | 2025-07-31 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for using plasma cell depleting agents and/or b cell depleting agents to suppress host anti-aav antibody response and enable aav transduction and re-dosing |
| US20250242018A1 (en) | 2024-01-26 | 2025-07-31 | Regeneron Pharmaceuticals, Inc. | Combination immunosuppression for inhibiting an immune response and enabling immunogen administration and re-administration |
| WO2025184567A1 (en) | 2024-03-01 | 2025-09-04 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for re-dosing aav using anti-cd40 antagonistic antibody to suppress host anti-aav antibody response |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
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| AU2021244215A1 (en) * | 2020-03-26 | 2022-10-13 | Seagen Inc. | Methods of treating multiple myeloma |
-
2017
- 2017-02-16 IL IL311107A patent/IL311107A/en unknown
- 2017-02-16 MX MX2018009700A patent/MX2018009700A/es unknown
- 2017-02-16 SG SG10202007836WA patent/SG10202007836WA/en unknown
- 2017-02-16 US US15/999,346 patent/US20190194338A1/en not_active Abandoned
- 2017-02-16 CN CN202211055564.6A patent/CN116063503A/zh active Pending
- 2017-02-16 IL IL260732A patent/IL260732B2/en unknown
- 2017-02-16 MA MA044254A patent/MA44254A/fr unknown
- 2017-02-16 KR KR1020187021211A patent/KR102816905B1/ko active Active
- 2017-02-16 SG SG11201806261XA patent/SG11201806261XA/en unknown
- 2017-02-16 US US15/434,921 patent/US20170233484A1/en not_active Abandoned
- 2017-02-16 AU AU2017219747A patent/AU2017219747B2/en active Active
- 2017-02-16 BR BR112018016697A patent/BR112018016697A2/pt unknown
- 2017-02-16 CA CA3011900A patent/CA3011900A1/en active Pending
- 2017-02-16 HK HK19101575.0A patent/HK1259075A1/zh unknown
- 2017-02-16 EP EP17753839.4A patent/EP3416687A4/en active Pending
- 2017-02-16 JP JP2018543153A patent/JP7152309B2/ja active Active
- 2017-02-16 CN CN201780011604.8A patent/CN108778329B/zh active Active
- 2017-02-16 WO PCT/US2017/018177 patent/WO2017143069A1/en not_active Ceased
-
2018
- 2018-08-09 MX MX2023000889A patent/MX2023000889A/es unknown
- 2018-10-03 US US16/151,012 patent/US20190023801A1/en not_active Abandoned
-
2019
- 2019-05-14 US US16/411,867 patent/US11078291B2/en active Active
-
2020
- 2020-02-17 JP JP2020024261A patent/JP2020073605A/ja active Pending
-
2021
- 2021-06-25 US US17/358,642 patent/US11767365B2/en active Active
-
2022
- 2022-03-01 JP JP2022030779A patent/JP2022069488A/ja not_active Withdrawn
-
2023
- 2023-08-15 US US18/449,876 patent/US20240109975A1/en not_active Abandoned
- 2023-12-14 AU AU2023282281A patent/AU2023282281A1/en active Pending
- 2023-12-22 JP JP2023216464A patent/JP2024019677A/ja active Pending
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