HK1259075A1 - Bcma抗體和其用以治療癌症和免疫病症的用途 - Google Patents
Bcma抗體和其用以治療癌症和免疫病症的用途Info
- Publication number
- HK1259075A1 HK1259075A1 HK19101575.0A HK19101575A HK1259075A1 HK 1259075 A1 HK1259075 A1 HK 1259075A1 HK 19101575 A HK19101575 A HK 19101575A HK 1259075 A1 HK1259075 A1 HK 1259075A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- same
- treat cancer
- immunological disorders
- bcma antibodies
- bcma
- Prior art date
Links
- 101100425747 Mus musculus Tnfrsf17 gene Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 208000026278 immune system disease Diseases 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- A61K38/05—Dipeptides
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/00—Immunoglobulins specific features
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662296594P | 2016-02-17 | 2016-02-17 | |
US201662396084P | 2016-09-16 | 2016-09-16 | |
PCT/US2017/018177 WO2017143069A1 (en) | 2016-02-17 | 2017-02-16 | Bcma antibodies and use of same to treat cancer and immunological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1259075A1 true HK1259075A1 (zh) | 2019-11-22 |
Family
ID=59562012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK19101575.0A HK1259075A1 (zh) | 2016-02-17 | 2019-01-29 | Bcma抗體和其用以治療癌症和免疫病症的用途 |
Country Status (14)
Country | Link |
---|---|
US (6) | US20170233484A1 (zh) |
EP (1) | EP3416687A4 (zh) |
JP (4) | JP7152309B2 (zh) |
KR (1) | KR20180107111A (zh) |
CN (2) | CN108778329B (zh) |
AU (2) | AU2017219747B2 (zh) |
BR (1) | BR112018016697A2 (zh) |
CA (1) | CA3011900A1 (zh) |
HK (1) | HK1259075A1 (zh) |
IL (2) | IL311107A (zh) |
MA (1) | MA44254A (zh) |
MX (1) | MX2018009700A (zh) |
SG (2) | SG10202007836WA (zh) |
WO (1) | WO2017143069A1 (zh) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017143069A1 (en) | 2016-02-17 | 2017-08-24 | Seattle Genetics, Inc. | Bcma antibodies and use of same to treat cancer and immunological disorders |
US11166985B2 (en) | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
AU2018367896B2 (en) | 2017-05-12 | 2023-06-01 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
CN112105420A (zh) | 2018-05-11 | 2020-12-18 | 克里斯珀医疗股份公司 | 用于治疗癌症的方法和组合物 |
EP3777895A4 (en) * | 2018-06-26 | 2021-12-22 | ABL Bio Inc. | ANTI-BCMA ANTIBODIES AND USES THEREOF |
EP3823664A1 (en) | 2018-07-19 | 2021-05-26 | Regeneron Pharmaceuticals, Inc. | Bispecific anti-bcma x anti-cd3 antibodies and uses thereof |
MX2021007327A (es) * | 2018-12-19 | 2021-09-08 | Seagen Inc | Fucosilacion controlada de anticuerpos. |
BR112021016791A2 (pt) * | 2019-02-26 | 2021-11-16 | Sorrento Therapeutics Inc | Proteínas de ligação de antígenos que se ligam a bcma |
WO2020191346A1 (en) | 2019-03-21 | 2020-09-24 | Regeneron Pharmaceuticals, Inc. | Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy |
AU2020267057A1 (en) | 2019-04-30 | 2021-11-18 | Crispr Therapeutics Ag | Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19 |
KR20220017914A (ko) * | 2019-05-07 | 2022-02-14 | 그라셀 바이오테크놀로지스 (상하이) 컴퍼니, 리미티드 | Bcma를 표적으로 하는 조작된 면역 세포 및 그의 용도 |
WO2020240502A2 (en) * | 2019-05-31 | 2020-12-03 | Medimmune, Llc | Combination therapy |
JP2022542088A (ja) * | 2019-07-30 | 2022-09-29 | シャンハイ ハンセン バイオメディカル カンパニー リミテッド | 抗bcma抗体、その抗原結合断片、及びそれらの医療用途 |
CN112409482B (zh) * | 2019-08-20 | 2022-08-26 | 杭州尚健生物技术有限公司 | Bcma抗体 |
WO2021136308A1 (en) * | 2020-01-03 | 2021-07-08 | Biosion Inc. | Antibodies binding bcma and uses thereof |
CN113248611A (zh) * | 2020-02-13 | 2021-08-13 | 湖南华康恒健生物技术有限公司 | 抗bcma抗体、其药物组合物及应用 |
CN115279781A (zh) * | 2020-03-26 | 2022-11-01 | 上海翰森生物医药科技有限公司 | 抗体药物偶联物及其医药用途 |
BR112022018987A2 (pt) | 2020-03-26 | 2022-11-01 | Seagen Inc | Métodos de tratamento de mieloma múltiplo |
EP4132588A1 (en) | 2020-04-10 | 2023-02-15 | Seagen Inc. | Charge variant linkers |
MX2023004941A (es) | 2020-11-08 | 2023-07-12 | Seagen Inc | Conjugado de anticuerpo y fármaco para terapia de combinación con inhibidor de células inmunitarias. |
EP4326333A1 (en) | 2021-04-20 | 2024-02-28 | Seagen Inc. | Modulation of antibody-dependent cellular cytotoxicity |
IL308795A (en) | 2021-05-28 | 2024-01-01 | Seagen Inc | Anthracycline antibody conjugates |
WO2023016564A1 (zh) | 2021-08-12 | 2023-02-16 | 上海才致药成生物科技有限公司 | 靶向GPC3的抗体干扰素α融合蛋白及其用途 |
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IL311107A (en) | 2024-04-01 |
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EP3416687A4 (en) | 2019-10-23 |
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