JP2019510737A - 高親和性ＩｇＥ受容体アルファ鎖（ＦｃｅＲＩａ） - Google Patents
高親和性ＩｇＥ受容体アルファ鎖（ＦｃｅＲＩａ） Download PDFInfo
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- 239000010452 phosphate Substances 0.000 description 1
- 230000010399 physical interaction Effects 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
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- 229920003023 plastic Polymers 0.000 description 1
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- 229920000642 polymer Polymers 0.000 description 1
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- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
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- 239000002244 precipitate Substances 0.000 description 1
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- 238000000159 protein binding assay Methods 0.000 description 1
- 239000012474 protein marker Substances 0.000 description 1
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- 238000001303 quality assessment method Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000011535 reaction buffer Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 210000003370 receptor cell Anatomy 0.000 description 1
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- 208000037851 severe atopic dermatitis Diseases 0.000 description 1
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- 230000011664 signaling Effects 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229960002317 succinimide Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 238000004885 tandem mass spectrometry Methods 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
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- 238000011269 treatment regimen Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16020009.3A EP3192806A1 (en) | 2016-01-13 | 2016-01-13 | Alpha chain of the high-affinity ige receptor (fceria) |
| EP16020009.3 | 2016-01-13 | ||
| PCT/EP2017/050646 WO2017121842A1 (en) | 2016-01-13 | 2017-01-13 | Alpha chain of the high-affinity ige receptor (fceria) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019510737A true JP2019510737A (ja) | 2019-04-18 |
| JP2019510737A5 JP2019510737A5 (enExample) | 2020-02-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536507A Withdrawn JP2019510737A (ja) | 2016-01-13 | 2017-01-13 | 高親和性ＩｇＥ受容体アルファ鎖（ＦｃｅＲＩａ） |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190127438A1 (enExample) |
| EP (2) | EP3192806A1 (enExample) |
| JP (1) | JP2019510737A (enExample) |
| CN (1) | CN108473551A (enExample) |
| AU (1) | AU2017207854A1 (enExample) |
| CA (1) | CA3010982A1 (enExample) |
| RU (1) | RU2018129024A (enExample) |
| WO (1) | WO2017121842A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022539684A (ja) * | 2019-07-08 | 2022-09-13 | ジーアイ イノベーション， インコーポレイテッド | 高シアル酸含量を有し、ＩｇＥ Ｆｃ受容体のアルファサブユニットの細胞外ドメインを含むポリペプチド二量体及び同ポリペプチド二量体を含む医薬組成物 |
| JP2023522574A (ja) * | 2020-03-26 | 2023-05-31 | ウニヴェルシテ トゥールーズ トロワジェーム－ポール サバティエ | リウマチ性関節炎治療用アフェレシスカラム |
| JP2023534024A (ja) * | 2020-07-17 | 2023-08-07 | ジーアイ イノベーション， インコーポレイテッド | Ｉｇｅ ｆｃ受容体アルファサブユニット細胞外ドメイン及び抗ｉｌ－４抗体を含む融合タンパク質並びにその融合タンパク質の使用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11060075B2 (en) | 2018-10-29 | 2021-07-13 | Codexis, Inc. | Engineered DNA polymerase variants |
| CN111100210B (zh) * | 2019-01-30 | 2022-04-19 | 武汉九州钰民医药科技有限公司 | 一种Fc融合蛋白及其应用 |
| CN110716054A (zh) * | 2019-09-11 | 2020-01-21 | 天津医科大学 | 一种血清亲细胞性免疫球蛋白e的定量检测试剂盒 |
| WO2024200553A1 (en) * | 2023-03-29 | 2024-10-03 | Grifols Worldwide Operations Limited | COMPOSITIONS AND METHODS OF PREPARATION OF BLOOD PLASMA PRODUCTS WITH REDUCED LEVELS OF FceRIß AUTOANTIBODIES |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4770774A (en) | 1985-09-19 | 1988-09-13 | Toray Industries, Inc. | Column for removing β2 -microglobulin |
| US5985599A (en) | 1986-05-29 | 1999-11-16 | The Austin Research Institute | FC receptor for immunoglobulin |
| US4962035A (en) | 1987-12-01 | 1990-10-09 | President And Fellows Of Harvard College | DNA encoding IgE receptor alpha-subunit or fragment thereof |
| DE69534187T2 (de) | 1994-05-13 | 2005-11-17 | Miltenyi Biotec Gmbh | Sterile und pyrogenfreie säulen, gekoppelt mit einem protein, zum binden und entfernen von substanzen aus dem blut |
| IL116436A (en) * | 1995-12-18 | 2006-12-31 | Yissum Res Dev Co | Fc?Á-PE CHIMERIC PROTEIN FOR TARGETED TREATMENT OF ALLERGY RESPONSES AND |
| MY120425A (en) | 1996-07-26 | 2005-10-31 | Novartis Ag | Fusion polypeptides |
| GB9715387D0 (en) | 1997-07-23 | 1997-09-24 | Gould Hannah J | Immunoglobulin-binding polypeptides and their use |
| US6057127A (en) * | 1998-01-29 | 2000-05-02 | Heska Corporation | Equine Fc epsilon receptor alpha chain nucleic acid molecules and uses thereof |
| EP1006183A1 (en) | 1998-12-03 | 2000-06-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Recombinant soluble Fc receptors |
| EP1214429A1 (en) * | 1999-09-21 | 2002-06-19 | Isis Innovation Limited | Modulation of ige receptor cell surface expression |
| AU2001273456A1 (en) * | 2000-07-13 | 2002-01-30 | Hyseq, Inc. | Soluble immunoglobulin e receptor alpha like molecules |
| US8354109B2 (en) | 2005-12-13 | 2013-01-15 | Suppremol Gmbh | Multimeric Fc receptor polypeptides |
| EP2696895A1 (en) | 2011-04-13 | 2014-02-19 | Biomay Ag | IMMUNOAFFINITY SEPARATION MATERIALS COMPRISING ANTI-IgE ANTIBODY DERIVATIVES |
| CN102660569B (zh) | 2012-04-21 | 2013-11-06 | 大连理工大学 | 一种重组人IgE受体蛋白的制备方法及应用 |
-
2016
- 2016-01-13 EP EP16020009.3A patent/EP3192806A1/en not_active Ceased
-
2017
- 2017-01-13 CN CN201780005678.0A patent/CN108473551A/zh active Pending
- 2017-01-13 AU AU2017207854A patent/AU2017207854A1/en not_active Abandoned
- 2017-01-13 WO PCT/EP2017/050646 patent/WO2017121842A1/en not_active Ceased
- 2017-01-13 EP EP17700360.5A patent/EP3402813A1/en not_active Withdrawn
- 2017-01-13 US US16/068,406 patent/US20190127438A1/en not_active Abandoned
- 2017-01-13 CA CA3010982A patent/CA3010982A1/en not_active Abandoned
- 2017-01-13 JP JP2018536507A patent/JP2019510737A/ja not_active Withdrawn
- 2017-01-13 RU RU2018129024A patent/RU2018129024A/ru not_active Application Discontinuation
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022539684A (ja) * | 2019-07-08 | 2022-09-13 | ジーアイ イノベーション， インコーポレイテッド | 高シアル酸含量を有し、ＩｇＥ Ｆｃ受容体のアルファサブユニットの細胞外ドメインを含むポリペプチド二量体及び同ポリペプチド二量体を含む医薬組成物 |
| JP7579815B2 (ja) | 2019-07-08 | 2024-11-08 | ジーアイ イノベーション， インコーポレイテッド | 高シアル酸含量を有し、ＩｇＥ Ｆｃ受容体のアルファサブユニットの細胞外ドメインを含むポリペプチド二量体及び同ポリペプチド二量体を含む医薬組成物 |
| US12409203B2 (en) | 2019-07-08 | 2025-09-09 | Gi Innovation, Inc. | Polypeptide dimer with high sialic acid content, comprising extracellular domain of alpha subunit of IGE FC receptor, and pharmaceutical composition comprising same |
| JP2023522574A (ja) * | 2020-03-26 | 2023-05-31 | ウニヴェルシテ トゥールーズ トロワジェーム－ポール サバティエ | リウマチ性関節炎治療用アフェレシスカラム |
| JP2023534024A (ja) * | 2020-07-17 | 2023-08-07 | ジーアイ イノベーション， インコーポレイテッド | Ｉｇｅ ｆｃ受容体アルファサブユニット細胞外ドメイン及び抗ｉｌ－４抗体を含む融合タンパク質並びにその融合タンパク質の使用 |
| JP7784412B2 (ja) | 2020-07-17 | 2025-12-11 | ジーアイ イノベーション， インコーポレイテッド | Ｉｇｅ ｆｃ受容体アルファサブユニット細胞外ドメイン及び抗ｉｌ－４抗体を含む融合タンパク質並びにその融合タンパク質の使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108473551A (zh) | 2018-08-31 |
| WO2017121842A1 (en) | 2017-07-20 |
| EP3402813A1 (en) | 2018-11-21 |
| AU2017207854A1 (en) | 2018-06-07 |
| EP3192806A1 (en) | 2017-07-19 |
| CA3010982A1 (en) | 2017-07-20 |
| US20190127438A1 (en) | 2019-05-02 |
| RU2018129024A (ru) | 2020-02-13 |
| RU2018129024A3 (enExample) | 2020-05-29 |
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