JP2019510509A5 - - Google Patents
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- JP2019510509A5 JP2019510509A5 JP2018561784A JP2018561784A JP2019510509A5 JP 2019510509 A5 JP2019510509 A5 JP 2019510509A5 JP 2018561784 A JP2018561784 A JP 2018561784A JP 2018561784 A JP2018561784 A JP 2018561784A JP 2019510509 A5 JP2019510509 A5 JP 2019510509A5
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- Prior art keywords
- cell
- cells
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- corneal endothelial
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020022800A JP7453669B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2020022799A JP6954682B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016026423 | 2016-02-15 | ||
| JP2016026426 | 2016-02-15 | ||
| JP2016026423 | 2016-02-15 | ||
| JP2016026424 | 2016-02-15 | ||
| JP2016026425 | 2016-02-15 | ||
| JP2016026424 | 2016-02-15 | ||
| JP2016026425 | 2016-02-15 | ||
| JP2016026426 | 2016-02-15 | ||
| JP2016077450 | 2016-04-07 | ||
| JP2016077450 | 2016-04-07 | ||
| PCT/JP2017/005386 WO2017141926A1 (en) | 2016-02-15 | 2017-02-14 | Human functional corneal endothelial cell and application thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020022800A Division JP7453669B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2020022799A Division JP6954682B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019510509A JP2019510509A (ja) | 2019-04-18 |
| JP2019510509A5 true JP2019510509A5 (https=) | 2020-04-02 |
| JP7008337B2 JP7008337B2 (ja) | 2022-02-10 |
Family
ID=58261691
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561784A Active JP7008337B2 (ja) | 2016-02-15 | 2017-02-14 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2020022799A Active JP6954682B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2020022800A Active JP7453669B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2023205812A Pending JP2024019306A (ja) | 2016-02-15 | 2023-12-06 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2025182944A Pending JP2026021433A (ja) | 2016-02-15 | 2025-10-29 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2025182943A Pending JP2026012325A (ja) | 2016-02-15 | 2025-10-29 | ヒト機能性角膜内皮細胞およびその応用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020022799A Active JP6954682B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2020022800A Active JP7453669B2 (ja) | 2016-02-15 | 2020-02-13 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2023205812A Pending JP2024019306A (ja) | 2016-02-15 | 2023-12-06 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2025182944A Pending JP2026021433A (ja) | 2016-02-15 | 2025-10-29 | ヒト機能性角膜内皮細胞およびその応用 |
| JP2025182943A Pending JP2026012325A (ja) | 2016-02-15 | 2025-10-29 | ヒト機能性角膜内皮細胞およびその応用 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20190083543A1 (https=) |
| EP (2) | EP3416658B1 (https=) |
| JP (6) | JP7008337B2 (https=) |
| ES (1) | ES2947826T3 (https=) |
| PL (1) | PL3416658T3 (https=) |
| WO (1) | WO2017141926A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2858173C (en) | 2011-12-06 | 2023-09-26 | Advanced Cell Technology, Inc. | Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof |
| EP3416658B1 (en) | 2016-02-15 | 2023-03-22 | Kyoto Prefectural Public University Corporation | Human functional corneal endothelial cell and application thereof |
| CN107629999A (zh) * | 2017-10-18 | 2018-01-26 | 清华大学深圳研究生院 | 一种增加间充质干细胞外泌体产生及分泌的方法 |
| US12350294B2 (en) | 2018-01-16 | 2025-07-08 | Keio University | Medium comprising serum replacement, IGF1, STAT3 activator and adrenal gland hormone without BFGF or rock inhibitor for producing corneal endothelial substitute cells from iPS cells and a method thereof |
| EP3893904A4 (en) * | 2018-12-12 | 2022-08-17 | The Johns Hopkins University | GENERATION AND CRYOPRESERVATION OF CLINICAL-QUALITY CORNEAL EDDELLIAL CELLS FROM PLURIPOTENTIC STEM CELLS |
| KR102446567B1 (ko) * | 2019-04-17 | 2022-09-26 | 연세대학교 산학협력단 | 각막 내피 세포의 기능 부전 진단용 바이오마커 |
| JP2020200296A (ja) * | 2019-06-13 | 2020-12-17 | 久貴 藤本 | 角膜内皮障害の予防及び／又は治療のための薬剤 |
| US12230397B2 (en) * | 2019-08-21 | 2025-02-18 | Case Western Reserve University | Assessment of endothelial cells and corneas at risk from ophthalmological images |
| WO2021172554A1 (ja) | 2020-02-27 | 2021-09-02 | 京都府公立大学法人 | ヒト機能性角膜内皮細胞およびその応用 |
| WO2022025239A1 (ja) * | 2020-07-31 | 2022-02-03 | 学校法人同志社 | 角膜内皮細胞注入療法の治療効果増強法 |
| AU2021366805B2 (en) * | 2020-10-22 | 2025-04-24 | Kyoto Prefectural Public University Corporation | A storage method of human corneal endothelial cells and/or human corneal endothelial precursor cells |
| CN112538458B (zh) * | 2020-11-26 | 2025-10-31 | 北京孟眸生物科技有限公司 | 用于重编程细胞的方法 |
| US20240350552A1 (en) | 2021-07-07 | 2024-10-24 | Cellusion Inc. | Therapeutic composition containing corneal endothelium replacement cells |
| WO2023282338A1 (ja) | 2021-07-07 | 2023-01-12 | 株式会社セルージョン | 細胞播種剤及び細胞移植用基材 |
| CN114507635B (zh) * | 2022-01-24 | 2024-03-22 | 上海纽仁生物医药科技有限公司 | 一种动物神经系统内皮细胞单细胞的分离方法 |
| WO2023190941A1 (ja) * | 2022-03-31 | 2023-10-05 | 学校法人同志社 | 培養由来成分を含まない角膜内皮細胞製剤及びその製造法 |
| WO2023230171A2 (en) * | 2022-05-24 | 2023-11-30 | University Of Pittsburgh - Of Thecommonwealth System Of Highereducation | Compositions and methods of treating corneal scarring |
| EP4655392A2 (en) * | 2023-01-27 | 2025-12-03 | Universiteit Maastricht | Methods for selecting cultured corneal endothelial cells |
| WO2024182683A1 (en) * | 2023-03-01 | 2024-09-06 | The Regents Of The University Of California | Rapid, accurate, and reproducible screening of endothelial cell morphology in diseased and healthy corneas |
| KR20250024502A (ko) * | 2023-08-11 | 2025-02-18 | 재단법인 아산사회복지재단 | 분화 유도된 각막 내피 세포를 포함하는 각막 질환 예방 또는 치료용 약학적 조성물 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4678783B1 (en) | 1983-11-04 | 1995-04-04 | Asahi Chemical Ind | Substituted isoquinolinesulfonyl compounds |
| EP1195372A1 (en) | 1994-04-18 | 2002-04-10 | Mitsubishi Pharma Corporation | N-heterocyclic substituted benzamide derivatives with antihypertensive activity |
| JP3421217B2 (ja) | 1995-11-20 | 2003-06-30 | 麒麟麦酒株式会社 | Ｒｈｏ標的タンパク質Ｒｈｏキナーゼ |
| AU9646198A (en) | 1997-10-22 | 1999-05-10 | Nippon Shinyaku Co. Ltd. | Isoquinoline derivative and drug |
| WO1999061403A1 (en) | 1998-05-25 | 1999-12-02 | Santen Pharmaceutical Co., Ltd. | Novel vinylbenzene derivatives |
| EP1020534B2 (en) | 1998-11-09 | 2011-01-05 | Eiken Kagaku Kabushiki Kaisha | Process for synthesizing nucleic acid |
| AU2878200A (en) | 1999-02-11 | 2000-08-29 | Schepens Eye Research Institute, Inc., The | Growth medium for human corneal endothelial cells |
| UY27224A1 (es) | 2001-03-23 | 2002-10-31 | Bayer Corp | Inhibidores de la rho-quinasa |
| PE20020958A1 (es) | 2001-03-23 | 2002-11-14 | Bayer Corp | Inhibidores de la rho-quinasa |
| US7109208B2 (en) | 2001-04-11 | 2006-09-19 | Senju Pharmaceutical Co., Ltd. | Visual function disorder improving agents |
| WO2002100833A1 (en) | 2001-06-12 | 2002-12-19 | Sumitomo Pharmaceuticals Company, Limited | Rho KINASE INHIBITORS |
| JP4505228B2 (ja) | 2002-01-10 | 2010-07-21 | バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト | Ｒｈｏ−キナーゼ阻害剤 |
| US6690307B2 (en) | 2002-01-22 | 2004-02-10 | Nokia Corporation | Adaptive variable length coding of digital video |
| MXPA04007196A (es) | 2002-01-23 | 2005-06-08 | Bayer Pharmaceuticals Corp | Inhibidores de rho-quinasa. |
| EP1541559A4 (en) | 2002-07-22 | 2007-08-22 | Asahi Kasei Pharma Corp | 5-SUBSTITUTED ISOQUINOLINE DERIVATIVE |
| CA2400996A1 (en) | 2002-09-03 | 2004-03-03 | Lisa Mckerracher | 1,4-substituted cyclohexane derivatives |
| US7160894B2 (en) | 2003-06-06 | 2007-01-09 | Asahi Kasei Pharma Corporation | Tricyclic compound |
| WO2005003101A2 (en) | 2003-07-02 | 2005-01-13 | Biofocus Discovery Limited | Pyrazine and pyridine derivatives as rho kinase inhibitors |
| WO2005039564A1 (en) | 2003-10-02 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | Phthalimide compounds useful as protein kinase inhibitors |
| WO2005034866A2 (en) | 2003-10-06 | 2005-04-21 | Glaxo Group Limited | Preparation of 1, 6, 7- trisubstituted azabenzimidazoles as kinase inhibitors |
| ES2387780T3 (es) | 2003-10-06 | 2012-10-01 | Glaxosmithkline Llc | Preparación de azabencimidazoles 1,6-disustituidos como inhibidores de quinasas |
| JP2007507547A (ja) | 2003-10-06 | 2007-03-29 | グラクソ グループ リミテッド | キナーゼ阻害剤としての１，７−二置換アザベンゾイミダゾールの調製 |
| JP2007015928A (ja) | 2003-10-15 | 2007-01-25 | Ube Ind Ltd | 新規オレフィン誘導体 |
| JP2007008816A (ja) | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| EP1679308B1 (en) | 2003-10-15 | 2013-07-24 | Ube Industries, Ltd. | Novel indazole derivative |
| CA2556589A1 (en) | 2004-02-24 | 2005-09-01 | Bioaxone Therapeutique Inc. | 4-substituted piperidine derivatives |
| AR049333A1 (es) | 2004-04-02 | 2006-07-19 | Vertex Pharma | Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas. |
| WO2006057270A1 (ja) | 2004-11-26 | 2006-06-01 | Asahi Kasei Pharma Corporation | 含窒素３環化合物 |
| CA2621181C (en) | 2005-08-30 | 2011-04-19 | Asahi Kasei Pharma Corporation | 5-isoquinolinesulfonamide compounds |
| WO2009028631A1 (ja) * | 2007-08-29 | 2009-03-05 | Senju Pharmaceutical Co., Ltd. | 角膜内皮細胞接着促進剤 |
| EP2249800B1 (en) * | 2008-02-04 | 2024-04-17 | Jeffrey L. Goldberg | Iron magnetic cells for localizing delivery and eye tissue repair |
| US8606848B2 (en) | 2009-09-10 | 2013-12-10 | Opentv, Inc. | Method and system for sharing digital media content |
| WO2011080984A1 (en) * | 2009-12-29 | 2011-07-07 | Senju Pharmaceutical Co., Ltd. | Therapeutic agent (y - 39983 ) for corneal endothelial dysfunction |
| JP5835693B2 (ja) * | 2010-02-05 | 2015-12-24 | 株式会社角膜再生研究所 | 角膜内皮細胞の培養方法、移植用角膜内皮細胞シートの製造方法および角膜内皮細胞培養キット |
| EP2547082B1 (en) | 2010-03-08 | 2019-06-26 | Nec Corporation | Mobile communication terminal apparatus, method for controlling power consumption of mobile communication terminal apparatus, and recording medium |
| KR102124149B1 (ko) | 2010-05-12 | 2020-06-18 | 인터디지탈 매디슨 페이튼트 홀딩스 | 통합된 유효성 맵 코딩을 위한 방법 및 장치 |
| EP2765188B1 (en) * | 2011-10-06 | 2017-12-06 | Keio University | Method for producing corneal endothelial cell |
| ES2897740T3 (es) * | 2011-12-28 | 2022-03-02 | Kyoto Prefectural Public Univ Corp | Normalización del cultivo de células endoteliales de la córnea |
| US9616101B2 (en) * | 2012-07-06 | 2017-04-11 | Kyoto Prefectural Public University Corporation | Differentiation marker and differentiation control of eye cell |
| US10017735B2 (en) | 2012-07-18 | 2018-07-10 | Singapore Health Services Pte Ltd | Cell culture of corneal endothelial cells |
| US10174284B2 (en) * | 2012-09-07 | 2019-01-08 | Jcr Pharmaceuticals Co., Ltd. | Medium, for culturing corneal endothelial cells, containing conditioned medium from mesenchymal stem cells |
| EP3029140A4 (en) | 2013-07-30 | 2017-06-28 | Kyoto Prefectural Public University Corporation | Corneal endothelial cell marker |
| WO2015072580A1 (ja) * | 2013-11-14 | 2015-05-21 | 学校法人同志社 | 細胞増殖促進または細胞障害抑制による角膜内皮治療薬 |
| JP2016077450A (ja) | 2014-10-15 | 2016-05-16 | タツタ電線株式会社 | 医療用チューブ |
| EP3416658B1 (en) | 2016-02-15 | 2023-03-22 | Kyoto Prefectural Public University Corporation | Human functional corneal endothelial cell and application thereof |
-
2017
- 2017-02-14 EP EP17709487.7A patent/EP3416658B1/en active Active
- 2017-02-14 JP JP2018561784A patent/JP7008337B2/ja active Active
- 2017-02-14 EP EP23160003.2A patent/EP4218773A1/en active Pending
- 2017-02-14 US US16/078,002 patent/US20190083543A1/en active Pending
- 2017-02-14 ES ES17709487T patent/ES2947826T3/es active Active
- 2017-02-14 PL PL17709487.7T patent/PL3416658T3/pl unknown
- 2017-02-14 WO PCT/JP2017/005386 patent/WO2017141926A1/en not_active Ceased
-
2020
- 2020-02-13 JP JP2020022799A patent/JP6954682B2/ja active Active
- 2020-02-13 JP JP2020022800A patent/JP7453669B2/ja active Active
- 2020-10-20 US US17/074,912 patent/US20210046124A1/en active Pending
-
2023
- 2023-12-06 JP JP2023205812A patent/JP2024019306A/ja active Pending
-
2025
- 2025-07-03 US US19/259,859 patent/US20260034177A1/en active Pending
- 2025-10-29 JP JP2025182944A patent/JP2026021433A/ja active Pending
- 2025-10-29 JP JP2025182943A patent/JP2026012325A/ja active Pending
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