JP2019509717A5 - - Google Patents

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Publication number
JP2019509717A5
JP2019509717A5 JP2018538718A JP2018538718A JP2019509717A5 JP 2019509717 A5 JP2019509717 A5 JP 2019509717A5 JP 2018538718 A JP2018538718 A JP 2018538718A JP 2018538718 A JP2018538718 A JP 2018538718A JP 2019509717 A5 JP2019509717 A5 JP 2019509717A5
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JP
Japan
Prior art keywords
residue
amino acid
polymerase
position corresponding
acid substitution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2018538718A
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English (en)
Japanese (ja)
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JP6934477B2 (ja
JP2019509717A (ja
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Priority claimed from PCT/US2017/014082 external-priority patent/WO2017127510A2/en
Publication of JP2019509717A publication Critical patent/JP2019509717A/ja
Publication of JP2019509717A5 publication Critical patent/JP2019509717A5/ja
Priority to JP2021135313A priority Critical patent/JP7256849B2/ja
Application granted granted Critical
Publication of JP6934477B2 publication Critical patent/JP6934477B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018538718A 2016-01-19 2017-01-19 熱安定逆転写酵素 Active JP6934477B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021135313A JP7256849B2 (ja) 2016-01-19 2021-08-23 熱安定逆転写酵素

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662280451P 2016-01-19 2016-01-19
US62/280,451 2016-01-19
PCT/US2017/014082 WO2017127510A2 (en) 2016-01-19 2017-01-19 Thermostable reverse transcriptase

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021135313A Division JP7256849B2 (ja) 2016-01-19 2021-08-23 熱安定逆転写酵素

Publications (3)

Publication Number Publication Date
JP2019509717A JP2019509717A (ja) 2019-04-11
JP2019509717A5 true JP2019509717A5 (enExample) 2020-02-27
JP6934477B2 JP6934477B2 (ja) 2021-09-15

Family

ID=59362774

Family Applications (2)

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JP2018538718A Active JP6934477B2 (ja) 2016-01-19 2017-01-19 熱安定逆転写酵素
JP2021135313A Active JP7256849B2 (ja) 2016-01-19 2021-08-23 熱安定逆転写酵素

Family Applications After (1)

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JP2021135313A Active JP7256849B2 (ja) 2016-01-19 2021-08-23 熱安定逆転写酵素

Country Status (4)

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US (3) US10323243B2 (enExample)
EP (2) EP3405578B1 (enExample)
JP (2) JP6934477B2 (enExample)
WO (1) WO2017127510A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017127510A2 (en) 2016-01-19 2017-07-27 Board Of Regents, The University Of Texas System Thermostable reverse transcriptase
WO2019023627A1 (en) * 2017-07-27 2019-01-31 Board Of Regents, The University Of Texas System AMPLIFICATION OF MRNA SEQUENCES ENCODING APPARIED PROTEINS
US11866785B2 (en) 2017-10-27 2024-01-09 Board Of Regents, The University Of Texas System Tumor specific antibodies and T-cell receptors and methods of identifying the same
EP4006147A4 (en) * 2019-07-26 2023-06-21 Toyobo Co., Ltd. VARIANT REVERSE TRANSCRIPTASE WITH EXCELLENT STABILITY
WO2024238992A1 (en) * 2023-05-18 2024-11-21 10X Genomics, Inc. Engineered non-strand displacing family b polymerases for reverse transcription and gap-fill applications
CN117778348B (zh) * 2023-12-12 2024-09-20 湖北大学 一种具有逆转录酶活性的Pfu DNA聚合酶突变体及其应用
US12467041B2 (en) 2023-12-12 2025-11-11 Hubei University Pfu DNA polymerase mutants with reverse transcriptase activity and their applications

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009486A1 (en) 1999-10-29 2004-01-15 Sorge Joseph A. Compositions and methods utilizing DNA polymerases
US20030228616A1 (en) * 1999-10-29 2003-12-11 Stratagene DNA polymerase mutants with reverse transcriptase activity
EP1154017B1 (en) * 2000-05-11 2010-01-20 Toyo Boseki Kabushiki Kaisha Modified thermostable dna polymerase from pyrococcus kodakarensis
GB0022458D0 (en) 2000-09-13 2000-11-01 Medical Res Council Directed evolution method
US20030134292A1 (en) 2001-10-30 2003-07-17 Farchaus Joseph W. Thermostable DNA polymerases and methods of making same
DE60231901D1 (de) * 2001-11-14 2009-05-20 Toyo Boseki Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon
US7932070B2 (en) 2001-12-21 2011-04-26 Agilent Technologies, Inc. High fidelity DNA polymerase compositions and uses therefor
US7148049B2 (en) 2002-04-02 2006-12-12 Roche Molecular Systems, Inc. Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activity
AU2004288017B2 (en) 2003-11-03 2009-10-08 United Kingdom Research And Innovation Polymerase
GB0325653D0 (en) 2003-11-03 2003-12-10 Medical Res Council CST emulsions
US20070048748A1 (en) 2004-09-24 2007-03-01 Li-Cor, Inc. Mutant polymerases for sequencing and genotyping
DK2074211T3 (da) 2006-09-06 2013-06-17 Medical Res Council DNA polymeraser til inkorporation af farvestof-mærkede nukleotid-analoger
EP2076592B1 (en) 2006-10-23 2017-04-12 Medical Research Council Polymerase
ES2571446T3 (es) 2008-11-03 2016-05-25 Kapa Biosystems Inc ADN polimerasas quiméricas
US20110301041A1 (en) * 2010-02-26 2011-12-08 Life Technologies Corporation Modified Proteins and Methods of Making and Using Same
GB201007384D0 (en) * 2010-04-30 2010-06-16 Medical Res Council Enzymes
WO2017127510A2 (en) 2016-01-19 2017-07-27 Board Of Regents, The University Of Texas System Thermostable reverse transcriptase

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