JP2019509281A5 - - Google Patents
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- Publication number
- JP2019509281A5 JP2019509281A5 JP2018545179A JP2018545179A JP2019509281A5 JP 2019509281 A5 JP2019509281 A5 JP 2019509281A5 JP 2018545179 A JP2018545179 A JP 2018545179A JP 2018545179 A JP2018545179 A JP 2018545179A JP 2019509281 A5 JP2019509281 A5 JP 2019509281A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- terbinafine
- derivative
- salt
- range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 40
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 16
- 150000003839 salts Chemical class 0.000 claims 15
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims 15
- 229960002722 terbinafine Drugs 0.000 claims 15
- 229920000642 polymer Polymers 0.000 claims 14
- 239000002105 nanoparticle Substances 0.000 claims 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 6
- 206010017533 Fungal infection Diseases 0.000 claims 5
- 208000031888 Mycoses Diseases 0.000 claims 4
- 241000894007 species Species 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- 206010034016 Paronychia Diseases 0.000 claims 2
- 229920002413 Polyhexanide Polymers 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 claims 1
- 229940123208 Biguanide Drugs 0.000 claims 1
- 208000007163 Dermatomycoses Diseases 0.000 claims 1
- 206010017543 Fungal skin infection Diseases 0.000 claims 1
- 208000010195 Onychomycosis Diseases 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 239000003205 fragrance Substances 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 206010040872 skin infection Diseases 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 201000004647 tinea pedis Diseases 0.000 claims 1
- 201000005882 tinea unguium Diseases 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023148797A JP2023182607A (ja) | 2016-03-25 | 2023-09-13 | 組成物および治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1605127.8A GB201605127D0 (en) | 2016-03-25 | 2016-03-25 | Composition and methods of treatment |
| GB1605127.8 | 2016-03-25 | ||
| PCT/GB2017/050852 WO2017163091A1 (en) | 2016-03-25 | 2017-03-24 | Composition and methods of treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023148797A Division JP2023182607A (ja) | 2016-03-25 | 2023-09-13 | 組成物および治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019509281A JP2019509281A (ja) | 2019-04-04 |
| JP2019509281A5 true JP2019509281A5 (enExample) | 2020-04-16 |
Family
ID=56027421
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545179A Pending JP2019509281A (ja) | 2016-03-25 | 2017-03-24 | 組成物および治療方法 |
| JP2023148797A Pending JP2023182607A (ja) | 2016-03-25 | 2023-09-13 | 組成物および治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023148797A Pending JP2023182607A (ja) | 2016-03-25 | 2023-09-13 | 組成物および治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200206160A1 (enExample) |
| EP (1) | EP3432867A1 (enExample) |
| JP (2) | JP2019509281A (enExample) |
| CN (2) | CN109562077A (enExample) |
| GB (1) | GB201605127D0 (enExample) |
| WO (1) | WO2017163091A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201710491D0 (en) * | 2017-06-30 | 2017-08-16 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
| EP4041839A4 (en) | 2019-10-08 | 2023-10-11 | Hallux, Inc. | ONYCHOMYCOSIS TREATMENT COMPOSITIONS AND METHODS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030147925A1 (en) * | 1998-09-11 | 2003-08-07 | Samuel P. Sawan | Topical dermal antimicrobial compositions, methods for generating same, and monitoring methods utilizing same |
| WO2011079234A2 (en) * | 2009-12-23 | 2011-06-30 | Nuvo Research Inc. | Highly permeating terbinafine formulation |
| JP2014501286A (ja) * | 2010-12-29 | 2014-01-20 | ストラテジック サイエンス アンド テクノロジーズ， エルエルシー | 真菌感染症および他の適応症に対する処置の経皮的送達 |
| EP2664327A1 (en) * | 2012-05-14 | 2013-11-20 | Almirall S.A. | Topical pharmaceutical compositions comprising terbinafide and urea |
| US8697753B1 (en) * | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| GB201317005D0 (en) * | 2013-09-25 | 2013-11-06 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
| GB201511799D0 (en) | 2015-07-06 | 2015-08-19 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
-
2016
- 2016-03-25 GB GBGB1605127.8A patent/GB201605127D0/en not_active Ceased
-
2017
- 2017-03-24 WO PCT/GB2017/050852 patent/WO2017163091A1/en not_active Ceased
- 2017-03-24 US US16/088,372 patent/US20200206160A1/en active Pending
- 2017-03-24 CN CN201780019759.6A patent/CN109562077A/zh active Pending
- 2017-03-24 JP JP2018545179A patent/JP2019509281A/ja active Pending
- 2017-03-24 CN CN202311073155.3A patent/CN117379391A/zh active Pending
- 2017-03-24 EP EP17715266.7A patent/EP3432867A1/en active Pending
-
2023
- 2023-09-13 JP JP2023148797A patent/JP2023182607A/ja active Pending
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