JP2019508447A5 - - Google Patents

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Publication number
JP2019508447A5
JP2019508447A5 JP2018548205A JP2018548205A JP2019508447A5 JP 2019508447 A5 JP2019508447 A5 JP 2019508447A5 JP 2018548205 A JP2018548205 A JP 2018548205A JP 2018548205 A JP2018548205 A JP 2018548205A JP 2019508447 A5 JP2019508447 A5 JP 2019508447A5
Authority
JP
Japan
Prior art keywords
pyridine
trifluoromethyl
imidazol
triazol
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018548205A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019508447A (ja
JP6970680B2 (ja
Filing date
Publication date
Priority claimed from US15/070,938 external-priority patent/US9896436B2/en
Application filed filed Critical
Priority claimed from PCT/US2017/022570 external-priority patent/WO2017161033A1/en
Publication of JP2019508447A publication Critical patent/JP2019508447A/ja
Publication of JP2019508447A5 publication Critical patent/JP2019508447A5/ja
Application granted granted Critical
Publication of JP6970680B2 publication Critical patent/JP6970680B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018548205A 2016-03-15 2017-03-15 ヒストンデメチラーゼ阻害剤 Expired - Fee Related JP6970680B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/070,938 2016-03-15
US15/070,938 US9896436B2 (en) 2014-09-16 2016-03-15 Histone demethylase inhibitors
PCT/US2017/022570 WO2017161033A1 (en) 2016-03-15 2017-03-15 Histone demethylase inhibitors

Publications (3)

Publication Number Publication Date
JP2019508447A JP2019508447A (ja) 2019-03-28
JP2019508447A5 true JP2019508447A5 (cg-RX-API-DMAC10.html) 2020-04-23
JP6970680B2 JP6970680B2 (ja) 2021-11-24

Family

ID=59852330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018548205A Expired - Fee Related JP6970680B2 (ja) 2016-03-15 2017-03-15 ヒストンデメチラーゼ阻害剤

Country Status (3)

Country Link
EP (1) EP3436445B1 (cg-RX-API-DMAC10.html)
JP (1) JP6970680B2 (cg-RX-API-DMAC10.html)
WO (1) WO2017161033A1 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10150754B2 (en) 2016-04-19 2018-12-11 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
MX2020005841A (es) * 2017-12-05 2020-09-07 Oryzon Genomics Sa Derivados de 1,2,4-oxadiazol como inhibidores de histona-desacetilasa 6.
CN108957004B (zh) * 2018-07-09 2021-10-19 东南大学 检测H3K9me2和H3K36me3表达量的试剂在制备胃癌预后评估试剂盒中的应用
CN114206868B (zh) 2019-06-06 2025-02-25 奥莱松基因组股份有限公司 作为hdac6抑制剂的3-(2-(杂芳基)-吡啶-4-基)-5-(三氟甲基)-1,2,4-噁二唑衍生物
CN114805357B (zh) * 2021-01-21 2023-12-19 四川大学 一种靶向setdb1-ttd的小分子抑制剂及其制药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101781663B1 (ko) * 2010-01-13 2017-09-25 템페로 파마슈티칼즈, 인크. 히스톤 데아세틸라제 효소를 억제하기 위한 화합물 및 이를 제조하는 방법
US8987461B2 (en) * 2012-12-06 2015-03-24 Quanticel Pharmaceuticals, Inc. Histone demethylase inhibitors
CA2903081A1 (en) * 2013-03-14 2014-09-25 Quanticel Pharmaceuticals, Inc. Histone demethylase inhibitors
WO2016007722A1 (en) * 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
CA2961525A1 (en) * 2014-09-16 2016-03-24 Celgene Quanticel Research, Inc. Histone demethylase inhibitors

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