JP2019502696A5 - - Google Patents
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- JP2019502696A5 JP2019502696A5 JP2018531529A JP2018531529A JP2019502696A5 JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5 JP 2018531529 A JP2018531529 A JP 2018531529A JP 2018531529 A JP2018531529 A JP 2018531529A JP 2019502696 A5 JP2019502696 A5 JP 2019502696A5
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- JP
- Japan
- Prior art keywords
- alkyl
- halo
- compound according
- disorder
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1522179.9 | 2015-12-16 | ||
| GBGB1522179.9A GB201522179D0 (en) | 2015-12-16 | 2015-12-16 | Novel compounds |
| PCT/GB2016/053958 WO2017103604A1 (en) | 2015-12-16 | 2016-12-16 | Hydantoin modulators of kv3 channels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019502696A JP2019502696A (ja) | 2019-01-31 |
| JP2019502696A5 true JP2019502696A5 (enExample) | 2020-02-06 |
| JP7036725B2 JP7036725B2 (ja) | 2022-03-15 |
Family
ID=55274838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531529A Expired - Fee Related JP7036725B2 (ja) | 2015-12-16 | 2016-12-16 | Kv3チャネルのヒダントインモジュレーター |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20200377485A1 (enExample) |
| EP (1) | EP3390394B1 (enExample) |
| JP (1) | JP7036725B2 (enExample) |
| CN (1) | CN108430995A (enExample) |
| BR (1) | BR112018012177A2 (enExample) |
| GB (1) | GB201522179D0 (enExample) |
| WO (1) | WO2017103604A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201521751D0 (en) | 2015-12-10 | 2016-01-27 | Autifony Therapeutics Ltd | Novel uses |
| GB201613163D0 (en) | 2016-07-29 | 2016-09-14 | Autifony Therapeutics Ltd | Novel compounds |
| US20200039970A1 (en) | 2016-12-16 | 2020-02-06 | Autifony Therapeutics Limited | Hydantoin modulators of kv3 channels |
| HRP20241318T1 (hr) | 2018-10-16 | 2024-12-20 | Autifony Therapeutics Limited | Novi spojevi |
| US12358901B2 (en) | 2018-10-16 | 2025-07-15 | Autifony Therapeutics Limited | KV3 modulators |
| TW202031645A (zh) | 2018-10-30 | 2020-09-01 | 丹麥商H 朗德貝克公司 | 作為Kv3鉀通道激活劑之芳基磺醯基吡咯甲醯胺衍生物 |
| US20220220095A1 (en) | 2019-04-26 | 2022-07-14 | H. Lundbeck A/S | N-((HETEROARYL)METHYL)-1-TOSYL-1H-PYRAZOLE-3-CARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS |
| WO2020216919A1 (en) | 2019-04-26 | 2020-10-29 | H. Lundbeck A/S | ARYLSULFONYLTHIOPHENECARBOXAMIDES AND ARYLSULFONYLFURANCARBOXAMIDES AS Kν3 POTASSIUM CHANNEL ACTIVATORS |
| PH12022551955A1 (en) * | 2020-02-06 | 2023-10-23 | Autifony Therapeutics Ltd | Novel compound |
| EP3901152A1 (en) * | 2020-04-23 | 2021-10-27 | F. Hoffmann-La Roche AG | Kv3 enhancers for the treatment of cognitive disorders |
| IL310160A (en) | 2021-08-10 | 2024-03-01 | Autifony Therapeutics Ltd | potassium channel modulators |
| WO2024121552A1 (en) | 2022-12-06 | 2024-06-13 | Autifony Therapeutics Limited | Compounds for the treatment of centra nervous system disorders |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6299383A (ja) * | 1985-10-28 | 1987-05-08 | Tokuyama Soda Co Ltd | エ−テル化合物の製造方法 |
| JP2005538155A (ja) * | 2002-09-05 | 2005-12-15 | メディヴィル・アクチボラグ | 非ヌクレオシド逆転写酵素インヒビター |
| US20050080100A1 (en) * | 2003-10-09 | 2005-04-14 | Pfizer Inc | Pyridylamino compounds and methods of use thereof |
| EP1845087A1 (en) * | 2006-04-14 | 2007-10-17 | Mutabilis SA | Hydroxyphenyl derivatives and biological applications thereof |
| PT2563776T (pt) * | 2010-04-27 | 2016-09-19 | Calcimedica Inc | Compostos que modulam o cálcio intracelular |
| US9346790B2 (en) * | 2010-12-06 | 2016-05-24 | Autifony Therapeutics Limited | Hydantoin derivatives useful as Kv3 inhibitors |
| US20120316182A1 (en) * | 2011-06-10 | 2012-12-13 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US20130030012A1 (en) * | 2011-07-27 | 2013-01-31 | Glaxo Group Limited | Compounds |
| BR112014028718A2 (pt) * | 2012-05-22 | 2017-06-27 | Autifony Therapeutics Ltd | derivados de hidantoína como inibidores de kv3 |
| WO2013182851A1 (en) * | 2012-06-06 | 2013-12-12 | Autifony Therapeutics Limited | Prophylaxis or treatment of diseases where a modulator of kv3.3 channels is required |
| JP6226967B2 (ja) * | 2012-06-06 | 2017-11-08 | ヴァンダービルト ケミカルズ、エルエルシー | 燃費効率がよい潤滑油 |
| CA2922567A1 (en) * | 2013-08-26 | 2015-03-05 | Purdue Pharma L.P. | Azaspiro[4.5]decane derivatives and use thereof |
-
2015
- 2015-12-16 GB GBGB1522179.9A patent/GB201522179D0/en not_active Ceased
-
2016
- 2016-12-16 CN CN201680074553.9A patent/CN108430995A/zh active Pending
- 2016-12-16 BR BR112018012177A patent/BR112018012177A2/pt not_active IP Right Cessation
- 2016-12-16 JP JP2018531529A patent/JP7036725B2/ja not_active Expired - Fee Related
- 2016-12-16 US US16/061,557 patent/US20200377485A1/en not_active Abandoned
- 2016-12-16 EP EP16816359.0A patent/EP3390394B1/en not_active Not-in-force
- 2016-12-16 WO PCT/GB2016/053958 patent/WO2017103604A1/en not_active Ceased
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