JP2019500850A5 - - Google Patents
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- Publication number
- JP2019500850A5 JP2019500850A5 JP2018521279A JP2018521279A JP2019500850A5 JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5 JP 2018521279 A JP2018521279 A JP 2018521279A JP 2018521279 A JP2018521279 A JP 2018521279A JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- receptor agonist
- cd137l
- agonist protein
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562245838P | 2015-10-23 | 2015-10-23 | |
| US62/245,838 | 2015-10-23 | ||
| PCT/EP2016/075543 WO2017068183A1 (en) | 2015-10-23 | 2016-10-24 | Single-chain cd137-receptor agonist proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019500850A JP2019500850A (ja) | 2019-01-17 |
| JP2019500850A5 true JP2019500850A5 (enExample) | 2019-12-05 |
| JP7033062B2 JP7033062B2 (ja) | 2022-03-09 |
Family
ID=57208274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018521279A Expired - Fee Related JP7033062B2 (ja) | 2015-10-23 | 2016-10-24 | 一本鎖ｃｄ１３７受容体アゴニストタンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10870688B2 (enExample) |
| EP (1) | EP3365448A1 (enExample) |
| JP (1) | JP7033062B2 (enExample) |
| CN (1) | CN108368511B (enExample) |
| AU (2) | AU2016341400B2 (enExample) |
| CA (1) | CA3002588C (enExample) |
| WO (1) | WO2017068183A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10576161B2 (en) | 2017-01-20 | 2020-03-03 | Magenta Therapeutics, Inc. | Compositions and methods for the depletion of CD137+ cells |
| WO2019109238A1 (en) | 2017-12-05 | 2019-06-13 | Lyvgen Biopharma Co., Ltd. | Anti-cd137 antibodies and uses thereof |
| CN113039201A (zh) * | 2018-09-28 | 2021-06-25 | 礼进生物医药科技（上海）有限公司 | 具有经过工程化的Fc结构域的抗CD137结合分子及其治疗用途 |
| JP7682102B2 (ja) | 2019-05-10 | 2025-05-23 | リビジェン バイオファーマ ホールディングス リミテッド | ヒト化抗ｃｄ１３７抗体およびその使用 |
| US20230212260A1 (en) | 2020-05-15 | 2023-07-06 | Apogenix Ag | Multi-specific immune modulators |
| KR102251580B1 (ko) * | 2020-08-14 | 2021-05-13 | 최상호 | 이중 보온관 접속용 레듀사 및 이를 이용한 시공방법 |
| WO2023088889A1 (en) | 2021-11-16 | 2023-05-25 | Apogenix Ag | CD137 ligands |
| WO2023088876A1 (en) | 2021-11-16 | 2023-05-25 | Apogenix Ag | Multi-specific immune modulators |
| WO2024088404A1 (en) * | 2022-10-28 | 2024-05-02 | Fbd Biologics Limited | Engineered 4-1bbl variants and methods of use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL202057B1 (pl) * | 1998-08-25 | 2009-05-29 | Merck Patent Gmbh | Homodimeryczne białko fuzyjne będące inhibitorem angiogenezy, sposób jego otrzymywania oraz cząsteczka DNA i wektor ekspresyjny zawierający to DNA |
| US20030223989A1 (en) * | 2002-04-18 | 2003-12-04 | Pluenneke John D. | CD137 agonists to treat patients with IgE-mediated conditions |
| JP2008537941A (ja) | 2005-03-31 | 2008-10-02 | ゼンコー・インコーポレイテッド | 最適化特性を有するＦｃ変異体 |
| PL2310509T3 (pl) * | 2008-07-21 | 2015-08-31 | Apogenix Ag | Jednołańcuchowe cząsteczki TNFSF |
| CA2822366A1 (en) | 2010-12-23 | 2012-06-28 | Janssen Biotech, Inc. | Active protease-resistant antibody fc mutants |
| WO2012130471A1 (en) * | 2011-04-01 | 2012-10-04 | Universität Stuttgart | Recombinant tnf ligand family member polypeptides with antibody binding domain and uses thereof |
| WO2013092998A1 (en) * | 2011-12-23 | 2013-06-27 | Innate Pharma | Enzymatic conjugation of antibodies |
| AU2016342420B2 (en) | 2015-10-23 | 2020-10-01 | Apogenix Ag | Single-chain LIGHT receptor agonist proteins |
| CN108430492B (zh) | 2015-10-23 | 2022-05-03 | 阿珀吉科吉尼科斯股份公司 | 单链cd27受体激动剂蛋白 |
-
2016
- 2016-10-24 CN CN201680073663.3A patent/CN108368511B/zh not_active Expired - Fee Related
- 2016-10-24 EP EP16787795.0A patent/EP3365448A1/en not_active Withdrawn
- 2016-10-24 AU AU2016341400A patent/AU2016341400B2/en not_active Ceased
- 2016-10-24 CA CA3002588A patent/CA3002588C/en active Active
- 2016-10-24 WO PCT/EP2016/075543 patent/WO2017068183A1/en not_active Ceased
- 2016-10-24 JP JP2018521279A patent/JP7033062B2/ja not_active Expired - Fee Related
-
2018
- 2018-04-17 US US15/955,086 patent/US10870688B2/en not_active Expired - Fee Related
-
2020
- 2020-12-21 US US17/128,678 patent/US20210246190A1/en not_active Abandoned
-
2021
- 2021-06-09 AU AU2021203792A patent/AU2021203792A1/en not_active Abandoned
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