JP2019500038A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019500038A5 JP2019500038A5 JP2018533724A JP2018533724A JP2019500038A5 JP 2019500038 A5 JP2019500038 A5 JP 2019500038A5 JP 2018533724 A JP2018533724 A JP 2018533724A JP 2018533724 A JP2018533724 A JP 2018533724A JP 2019500038 A5 JP2019500038 A5 JP 2019500038A5
- Authority
- JP
- Japan
- Prior art keywords
- cell culture
- bag
- unit
- control
- fully automatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004113 cell culture Methods 0.000 claims description 366
- 239000000523 sample Substances 0.000 claims description 126
- 239000007789 gas Substances 0.000 claims description 119
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 103
- 229910052760 oxygen Inorganic materials 0.000 claims description 103
- 239000001301 oxygen Substances 0.000 claims description 103
- 239000007788 liquid Substances 0.000 claims description 95
- 238000010438 heat treatment Methods 0.000 claims description 69
- 238000005286 illumination Methods 0.000 claims description 65
- 230000007246 mechanism Effects 0.000 claims description 65
- 238000006243 chemical reaction Methods 0.000 claims description 58
- 238000001514 detection method Methods 0.000 claims description 44
- 238000003780 insertion Methods 0.000 claims description 36
- 230000037431 insertion Effects 0.000 claims description 36
- 238000005192 partition Methods 0.000 claims description 34
- 238000002156 mixing Methods 0.000 claims description 33
- 230000002572 peristaltic effect Effects 0.000 claims description 32
- 239000000758 substrate Substances 0.000 claims description 29
- 239000010410 layer Substances 0.000 claims description 28
- 239000000463 material Substances 0.000 claims description 27
- 239000004698 Polyethylene Substances 0.000 claims description 22
- 229920000573 polyethylene Polymers 0.000 claims description 22
- 230000008859 change Effects 0.000 claims description 18
- 238000011084 recovery Methods 0.000 claims description 17
- -1 polyethylene Polymers 0.000 claims description 13
- 230000033001 locomotion Effects 0.000 claims description 12
- 239000002131 composite material Substances 0.000 claims description 11
- 239000006143 cell culture medium Substances 0.000 claims description 10
- 230000010261 cell growth Effects 0.000 claims description 10
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 10
- 230000010355 oscillation Effects 0.000 claims description 10
- 239000012790 adhesive layer Substances 0.000 claims description 8
- 239000012930 cell culture fluid Substances 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 230000005611 electricity Effects 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 5
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 4
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims description 4
- 239000005977 Ethylene Substances 0.000 claims description 4
- 238000009825 accumulation Methods 0.000 claims description 4
- 229920006026 co-polymeric resin Polymers 0.000 claims description 4
- 210000004027 cell Anatomy 0.000 description 90
- 239000000243 solution Substances 0.000 description 47
- 238000000034 method Methods 0.000 description 26
- 230000008569 process Effects 0.000 description 19
- 229920001296 polysiloxane Polymers 0.000 description 17
- 238000010008 shearing Methods 0.000 description 16
- 238000002845 discoloration Methods 0.000 description 15
- 238000013461 design Methods 0.000 description 13
- 238000010586 diagram Methods 0.000 description 13
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 12
- 239000003570 air Substances 0.000 description 12
- 230000001939 inductive effect Effects 0.000 description 11
- 238000011109 contamination Methods 0.000 description 9
- 238000012258 culturing Methods 0.000 description 8
- 238000012604 3D cell culture Methods 0.000 description 7
- 230000009471 action Effects 0.000 description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 description 6
- 239000001963 growth medium Substances 0.000 description 6
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 230000005779 cell damage Effects 0.000 description 5
- 208000037887 cell injury Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000001569 carbon dioxide Substances 0.000 description 4
- 238000011049 filling Methods 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 230000001360 synchronised effect Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000009529 body temperature measurement Methods 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000007793 ph indicator Substances 0.000 description 3
- 230000008054 signal transmission Effects 0.000 description 3
- 239000012086 standard solution Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 229930182555 Penicillin Natural products 0.000 description 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
- QTENRWWVYAAPBI-YZTFXSNBSA-N Streptomycin sulfate Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@H]1[C@H](N=C(N)N)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]1O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@H]1[C@H](N=C(N)N)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]1O QTENRWWVYAAPBI-YZTFXSNBSA-N 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 210000002865 immune cell Anatomy 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229940049954 penicillin Drugs 0.000 description 2
- 238000006552 photochemical reaction Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 241000233866 Fungi Species 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 238000013473 artificial intelligence Methods 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001577 neostriatum Anatomy 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 210000003934 vacuole Anatomy 0.000 description 1
Images
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510981653.7 | 2015-12-23 | ||
| CN201510981648.6 | 2015-12-23 | ||
| CN201510981653.7A CN105385587B (zh) | 2015-12-23 | 2015-12-23 | 一种非接触式传感器接头及其应用 |
| CN201510981648.6A CN105385597B (zh) | 2015-12-23 | 2015-12-23 | 一种细胞培养袋及其应用 |
| CN201610131141.6 | 2016-03-08 | ||
| CN201610131142.0 | 2016-03-08 | ||
| CN201610131142.0A CN105567566B (zh) | 2016-03-08 | 2016-03-08 | 一种连续细胞培养摇床用培养袋托架 |
| CN201610131141.6A CN105567565B (zh) | 2016-03-08 | 2016-03-08 | 一种连续细胞培养摇床 |
| CN201610325563.7A CN105785560B (zh) | 2016-05-16 | 2016-05-16 | 用于细胞培养在线观察的暗视场显微镜 |
| CN201610325576.4A CN105925481A (zh) | 2016-05-16 | 2016-05-16 | 全自动细胞连续培养系统 |
| CN201610325576.4 | 2016-05-16 | ||
| CN201610325563.7 | 2016-05-16 | ||
| PCT/CN2016/110035 WO2017107837A1 (zh) | 2015-12-23 | 2016-12-15 | 全自动细胞连续培养系统 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019500038A JP2019500038A (ja) | 2019-01-10 |
| JP2019500038A5 true JP2019500038A5 (enExample) | 2019-04-11 |
| JP6889723B2 JP6889723B2 (ja) | 2021-06-18 |
Family
ID=59089117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018533724A Expired - Fee Related JP6889723B2 (ja) | 2015-12-23 | 2016-12-15 | 細胞培養装置 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US10934513B2 (enExample) |
| JP (1) | JP6889723B2 (enExample) |
| WO (1) | WO2017107837A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015028167B1 (pt) * | 2013-05-07 | 2021-06-22 | Biosafe S.A. | Dispositivo para mistura de amostras biológicas, método de mistura de amostras biológicas, e, uso do dispositivo |
| CA3036691A1 (en) * | 2016-09-14 | 2018-03-22 | Vbc Holdings Llc | Systems, apparatus and methods for controlling a movement of a cell culture to optimize cell growth |
| CN107794222A (zh) * | 2017-10-25 | 2018-03-13 | 广州新诚生物科技有限公司 | 模拟体内动态微环境的细胞培养装置 |
| CN107904166B (zh) * | 2017-11-15 | 2023-06-06 | 中国航天员科研训练中心 | 能实现能实时地线监测和远程监控的细胞培养系统 |
| DE102017130093B4 (de) * | 2017-12-15 | 2019-11-21 | Sartorius Stedim Biotech Gmbh | Vorrichtungsanordnung für die Durchführung wenigstens einer Grundoperation in einem biopharmazeutischen Prozess |
| WO2019131626A1 (ja) * | 2017-12-28 | 2019-07-04 | オリンパス株式会社 | 細胞培養制御方法、細胞培養制御装置、細胞培養装置および細胞培養システム |
| DE102018108323B4 (de) * | 2018-04-09 | 2020-07-09 | Schott Ag | Vorrichtung zur Halterung einer bilderfassenden Einrichtung an einem Bioreaktor, Bioreaktor mit Vorrichtung zur Halterung einer bilderfassenden Einrichtung sowie Verfahren zur Vermehrung oder Kultivierung biologischen Materials |
| CN108949561A (zh) * | 2018-08-27 | 2018-12-07 | 威海正生生物科技有限公司 | 智能免疫细胞培养震荡器 |
| US11518971B2 (en) | 2018-11-27 | 2022-12-06 | Research Triangle Institute | Method and apparatus for spatial control of cellular growth |
| CN109852546B (zh) * | 2019-04-03 | 2020-01-31 | 崔建英 | 一种细胞免污染培养系统及方法 |
| CN111979088B (zh) * | 2019-05-23 | 2022-08-26 | 比欧联科供应链管理(北京)有限公司 | 一种透气袋正反向灌流细胞培养装置及培养方法 |
| EP3990610A4 (en) | 2019-06-30 | 2023-11-01 | Saint-Gobain Performance Plastics Corporation | CELL CULTURE SYSTEM |
| CN110358684A (zh) * | 2019-08-16 | 2019-10-22 | 世翱（上海）生物医药科技有限公司 | 一种细胞自动培养装置及其使用方法 |
| DE102019126594B4 (de) * | 2019-10-02 | 2022-01-20 | Sartorius Stedim Biotech Gmbh | Bioprozesstechnisches Funktionsmodul |
| CN110938543A (zh) * | 2019-11-26 | 2020-03-31 | 浙江大学 | 一种用于细胞、组织培养的生物反应器 |
| CN110975723A (zh) * | 2019-12-23 | 2020-04-10 | 山东中惠仪器有限公司 | 便携式标准油样快速配制装置及配制方法 |
| CN113736651B (zh) * | 2020-05-29 | 2025-07-29 | 乾境生物技术有限公司 | 自动化细胞培养装置 |
| CN112608847A (zh) * | 2021-01-27 | 2021-04-06 | 张海甄 | 一种生物细胞培育用密封培育装置及其使用方法 |
| US11299700B1 (en) | 2021-02-19 | 2022-04-12 | Acequia Biotechnology, Llc | Bioreactor containers and methods of growing hairy roots using the same |
| CN113156100B (zh) * | 2021-04-29 | 2022-04-26 | 南阳理工学院 | 一种基于人工智能的肿瘤耐药性检测装置 |
| CN113621489A (zh) * | 2021-08-10 | 2021-11-09 | 安徽惠恩生物科技股份有限公司 | 一种冲质干细胞因子精华液的培养方法及其震荡装置 |
| CN113736655B (zh) * | 2021-09-13 | 2024-08-06 | 衷博瑞佳生物技术(上海)有限公司 | 一种生物细胞培养系统 |
| WO2023080902A1 (en) * | 2021-11-08 | 2023-05-11 | Tecan Trading Ag | Dark-field imaging system |
| CN113930340B (zh) * | 2021-11-24 | 2025-01-28 | 湖南开启时代生物科技有限责任公司 | 一种用于贴壁细胞培养的细胞培养箱 |
| CN114192029A (zh) * | 2021-12-07 | 2022-03-18 | 苏州培英实验设备有限公司 | 一种无污染、便捷化摇床及其工作方法 |
| CN114308177B (zh) * | 2021-12-30 | 2023-02-10 | 昕慕(江苏)生物医药科技有限公司 | 一种细胞培养袋用细胞收获支架及使用方法 |
| WO2023141621A2 (en) * | 2022-01-24 | 2023-07-27 | Octane Biotech Inc. | Support structures for automated cell engineering systems |
| CN114717113B (zh) * | 2022-04-11 | 2023-03-24 | 上海乐纯乐新材料有限公司 | 一种用于恒流补液的细胞培养袋 |
| CN115232747B (zh) * | 2022-09-02 | 2023-06-06 | 烟台硕博源生物技术有限公司 | 一种基于微流控制的全自动干细胞培养扩增装置 |
| CN115747064A (zh) * | 2022-12-30 | 2023-03-07 | 浙江金仪盛世生物工程有限公司 | 大型激流式生物反应器 |
| CN115820420B (zh) * | 2023-02-17 | 2023-05-09 | 海迈医疗科技(苏州)有限公司 | 培养设备及其使用方法 |
| TWI833614B (zh) * | 2023-03-23 | 2024-02-21 | 揚朋科技股份有限公司 | 細胞製備系統 |
| CN116376697A (zh) * | 2023-04-28 | 2023-07-04 | 东富龙生命科技有限公司 | 一种细胞培养系统及方法 |
| CN117158412B (zh) * | 2023-09-06 | 2025-12-30 | 江苏康进医疗器材有限公司 | 一种细胞液存储装置 |
| CN119246192A (zh) * | 2024-04-10 | 2025-01-03 | 青岛优瑞达生物科技有限公司 | 一种细胞检测装置 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003257569A1 (en) | 2002-08-28 | 2004-03-19 | Makoto Fujii | Culture system, detection and analysis system and detection method for cancer cell colonies |
| US7799559B2 (en) * | 2003-10-24 | 2010-09-21 | Olympus Corporation | Culture microscope apparatus |
| US7339671B2 (en) * | 2004-01-20 | 2008-03-04 | Hong Peng | Apparatus and method for monitoring biological cell culture |
| CA2613311A1 (en) | 2004-06-23 | 2006-01-05 | Rosemary Katherine Cameron Sharpin | Improvements in and relating to micro-organism test apparatus and methods of using the same |
| CN101048492B (zh) * | 2004-11-09 | 2013-01-09 | 株式会社钟化 | 细胞培养装置、图像处理装置和细胞检测系统 |
| US9512392B2 (en) * | 2006-06-08 | 2016-12-06 | Zhejiang Jinyishengshi Bioengineering Co., Ltd | Method to increase dissolved oxygen in a culture vessel |
| CN102086438B (zh) * | 2009-12-07 | 2012-12-19 | 韩春茂 | 用于细胞或组织工程生物培养的装置和方法 |
| US20130038727A1 (en) * | 2010-01-20 | 2013-02-14 | Phillip Clark | Cell Image Capturing and Remote Monitoring Systems |
| EP2686415B1 (en) * | 2011-03-18 | 2017-11-15 | GE Healthcare Bio-Sciences AB | Flexible bag for cultivation of cells |
| JP5786444B2 (ja) * | 2011-05-17 | 2015-09-30 | 東洋製罐グループホールディングス株式会社 | 細胞培養方法、及び細胞培養システム |
| JP5892594B2 (ja) * | 2012-01-24 | 2016-03-23 | 学校法人東京電機大学 | 複数点照明による培養細胞観察システム |
| CN203382764U (zh) | 2013-07-19 | 2014-01-08 | 广州中玺医疗科技有限公司 | 细胞增殖袋及细胞增殖装置 |
| JP6219214B2 (ja) * | 2014-03-31 | 2017-10-25 | 富士フイルム株式会社 | 細胞撮像制御装置および方法並びにプログラム |
| DE102014105472B4 (de) * | 2014-04-16 | 2016-03-17 | Sartorius Stedim Biotech Gmbh | Misch- und Auftauvorrichtung |
| WO2015174356A1 (ja) * | 2014-05-14 | 2015-11-19 | オリンパス株式会社 | 培養観察装置 |
| CN204439923U (zh) | 2015-03-05 | 2015-07-01 | 北京大学 | 一种暗场显微镜 |
| EP3211469B1 (en) * | 2015-03-31 | 2019-09-25 | Olympus Corporation | Observation device and observation method |
| EP3305885B1 (en) * | 2015-05-25 | 2021-03-24 | Nipro Corporation | Culturing device |
| CN108138116A (zh) * | 2015-08-25 | 2018-06-08 | 通用电气公司 | 在生物制造设备中和涉及其的改进 |
| CN105785560B (zh) | 2016-05-16 | 2022-11-08 | 上海吉倍生物技术有限公司 | 用于细胞培养在线观察的暗视场显微镜 |
| CN105567565B (zh) | 2016-03-08 | 2018-04-17 | 上海吉倍生物技术有限公司 | 一种连续细胞培养摇床 |
| CN105385587B (zh) | 2015-12-23 | 2017-12-05 | 上海吉凯基因科技有限公司 | 一种非接触式传感器接头及其应用 |
| CN105567566B (zh) | 2016-03-08 | 2018-04-17 | 上海吉倍生物技术有限公司 | 一种连续细胞培养摇床用培养袋托架 |
| CN105385597B (zh) | 2015-12-23 | 2018-10-12 | 上海吉倍生物技术有限公司 | 一种细胞培养袋及其应用 |
| CN105925481A (zh) | 2016-05-16 | 2016-09-07 | 上海吉凯基因科技有限公司 | 全自动细胞连续培养系统 |
-
2016
- 2016-12-15 JP JP2018533724A patent/JP6889723B2/ja not_active Expired - Fee Related
- 2016-12-15 US US16/064,414 patent/US10934513B2/en not_active Expired - Fee Related
- 2016-12-15 WO PCT/CN2016/110035 patent/WO2017107837A1/zh not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6889723B2 (ja) | 細胞培養装置 | |
| US20240295572A1 (en) | Incubation system and method for automated cell culture and testing | |
| US12098358B2 (en) | Automated incubator with robotic transport | |
| CN206014938U (zh) | 全自动细胞连续培养系统 | |
| CN105925481A (zh) | 全自动细胞连续培养系统 | |
| US7754478B2 (en) | Device for cell culture | |
| BRPI1012879B1 (pt) | sistema e método para ventilação e amostragem automáticas de um recipiente de espécime de cultura | |
| CN108795762A (zh) | 一种时差成像培养系统及其方法 | |
| CN106525803B (zh) | 生物成像仪 | |
| US20160184817A1 (en) | Cap for monitoring objects in suspension | |
| CN109060641A (zh) | 多孔进样细胞计数仪 | |
| TWM641788U (zh) | 整合性自動化細胞培養裝置 | |
| CN100561203C (zh) | 用于生化反应器的在线细胞显微观察仪 | |
| JP5672342B2 (ja) | 計数用装置 | |
| CN110793904A (zh) | 微滴读数仪 | |
| CN109306324B (zh) | 细胞培养及检测装置 | |
| CN115386489A (zh) | 一种胚胎时差培养系统 | |
| CN110358684A (zh) | 一种细胞自动培养装置及其使用方法 | |
| CN114085776B (zh) | 一种贴壁细胞培养系统 | |
| CN205750090U (zh) | 用于细胞培养在线观察的暗视场显微镜 | |
| CN204814273U (zh) | 一种显微镜肠系膜微循环观察用载物装置 | |
| CN210834687U (zh) | 一种多功能分析仪器 | |
| CN115290912A (zh) | 一种全自动凝血分析仪及其测试系统 | |
| CN205473822U (zh) | 一种连续细胞培养摇床用培养袋托架 | |
| CN222885630U (zh) | 多功能模块化光学实验装置 |