JP2019182865A5 - - Google Patents
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- Publication number
- JP2019182865A5 JP2019182865A5 JP2019076854A JP2019076854A JP2019182865A5 JP 2019182865 A5 JP2019182865 A5 JP 2019182865A5 JP 2019076854 A JP2019076854 A JP 2019076854A JP 2019076854 A JP2019076854 A JP 2019076854A JP 2019182865 A5 JP2019182865 A5 JP 2019182865A5
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- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- pharmaceutical composition
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 229910052736 halogen Inorganic materials 0.000 claims 5
- 150000002367 halogens Chemical class 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 125000000304 alkynyl group Chemical group 0.000 claims 3
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- 125000002837 carbocyclic group Chemical group 0.000 claims 3
- 125000003302 alkenyloxy group Chemical group 0.000 claims 2
- 150000001345 alkine derivatives Chemical class 0.000 claims 2
- 125000005133 alkynyloxy group Chemical group 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 102100037602 P2X purinoceptor 7 Human genes 0.000 claims 1
- 101710189965 P2X purinoceptor 7 Proteins 0.000 claims 1
- 125000006323 alkenyl amino group Chemical group 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 1
- -1 alkyl compound Chemical class 0.000 claims 1
- 125000006319 alkynyl amino group Chemical group 0.000 claims 1
- 125000001164 benzothiazolyl group Chemical group S1C(=NC2=C1C=CC=C2)* 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018078093 | 2018-04-16 | ||
| JP2018078093 | 2018-04-16 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019182865A JP2019182865A (ja) | 2019-10-24 |
| JP2019182865A5 true JP2019182865A5 (enExample) | 2022-04-18 |
| JP7311944B2 JP7311944B2 (ja) | 2023-07-20 |
Family
ID=68339653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019076854A Active JP7311944B2 (ja) | 2018-04-16 | 2019-04-15 | 二環性含窒素複素環誘導体を含有する医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP7311944B2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3199714A1 (en) * | 2020-11-20 | 2022-05-27 | Isao Miyazaki | Brain-migrating tumor therapeutic agent containing fused pyrimidine compound as active ingredient |
| WO2022114122A1 (ja) | 2020-11-30 | 2022-06-02 | 旭化成ファーマ株式会社 | 神経障害性疼痛を緩和させるための医薬 |
| TW202302541A (zh) * | 2021-03-17 | 2023-01-16 | 美商翰森生物有限責任公司 | 含氮雜環酮、其製備方法和醫藥用途 |
| JP2024178473A (ja) * | 2021-09-03 | 2024-12-25 | 塩野義製薬株式会社 | ウイルス増殖阻害活性を有する二環性含窒素複素環誘導体およびそれらを含有する医薬組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9988390B2 (en) * | 2015-10-30 | 2018-06-05 | F. Hoffmann-La Roche Ag | Pyrimidone derivatives and their use in the treatment, amelioration or prevention of a viral disease |
| EP3527568A4 (en) * | 2016-10-17 | 2020-03-18 | Shionogi & Co., Ltd | BICYCLIC NITROGENATED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREFOR |
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2019
- 2019-04-15 JP JP2019076854A patent/JP7311944B2/ja active Active