JP2018535668A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018535668A5 JP2018535668A5 JP2018519710A JP2018519710A JP2018535668A5 JP 2018535668 A5 JP2018535668 A5 JP 2018535668A5 JP 2018519710 A JP2018519710 A JP 2018519710A JP 2018519710 A JP2018519710 A JP 2018519710A JP 2018535668 A5 JP2018535668 A5 JP 2018535668A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen recognition
- recognition construct
- tcr
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15190230.1A EP3156067A1 (en) | 2015-10-16 | 2015-10-16 | High avidity hpv t-cell receptors |
| EP15190230.1 | 2015-10-16 | ||
| PCT/EP2016/074612 WO2017064198A1 (en) | 2015-10-16 | 2016-10-13 | High avidity hpv t-cell receptors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535668A JP2018535668A (ja) | 2018-12-06 |
| JP2018535668A5 true JP2018535668A5 (OSRAM) | 2019-11-21 |
| JP7000315B2 JP7000315B2 (ja) | 2022-02-04 |
Family
ID=54359849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519710A Expired - Fee Related JP7000315B2 (ja) | 2015-10-16 | 2016-10-13 | 高結合活性ｈｐｖ ｔ細胞受容体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11401316B2 (OSRAM) |
| EP (2) | EP3156067A1 (OSRAM) |
| JP (1) | JP7000315B2 (OSRAM) |
| CN (1) | CN108135998B (OSRAM) |
| AU (1) | AU2016336817C1 (OSRAM) |
| CA (1) | CA3001395A1 (OSRAM) |
| WO (1) | WO2017064198A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017096329A1 (en) | 2015-12-03 | 2017-06-08 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| DE102017114737A1 (de) | 2017-06-30 | 2019-01-03 | Immatics Biotechnologies Gmbh | Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie |
| WO2019070541A1 (en) | 2017-10-03 | 2019-04-11 | Juno Therapeutics, Inc. | HPV-SPECIFIC BINDING MOLECULES |
| CN109053879B (zh) * | 2018-08-22 | 2020-12-25 | 深圳市宝安区中心医院 | 一种治疗宫颈癌的scFv抗体及其应用 |
| WO2020214957A1 (en) | 2019-04-19 | 2020-10-22 | Tcrcure Biopharma Corp. | Anti-pd-1 antibodies and uses thereof |
| CN113072635B (zh) * | 2020-01-06 | 2023-08-25 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv抗原的t细胞受体及其编码序列 |
| WO2021155518A1 (en) * | 2020-02-05 | 2021-08-12 | Tcrcure Biopharma Corp | Anti-hpv t cell receptors and engineered cells |
| CN113321726B (zh) * | 2020-02-28 | 2024-05-28 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv的t细胞受体 |
| EP4125949A4 (en) * | 2020-03-23 | 2024-05-22 | The Council of the Queensland Institute of Medical Research | Compositions and methods for targeting hpv-infected cells |
| CN116096740A (zh) * | 2020-06-09 | 2023-05-09 | 得克萨斯州大学系统董事会 | 经改造t细胞受体和使用方法 |
| WO2022060904A1 (en) | 2020-09-16 | 2022-03-24 | Obsidian Therapeutics, Inc. | Compositions and methods for expression of t-cell receptors with small molecule-regulated cd40l in t cells |
| CN114539385A (zh) * | 2020-11-26 | 2022-05-27 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv抗原的tcr |
| CN114853878A (zh) * | 2021-02-03 | 2022-08-05 | 香雪生命科学技术（广东）有限公司 | 一种针对hpv的高亲和力tcr |
| US20240108654A1 (en) | 2021-03-03 | 2024-04-04 | Juno Therapeutics, Inc. | Combination of a t cell therapy and a dgk inhibitor |
| WO2023014337A1 (en) * | 2021-08-04 | 2023-02-09 | GUERRERO PRESTON Rafael | Viral and host biomarkers for early detection, therapeutic effectiveness, and relapse monitoring of cancer linked to severe acute respiratory syndrome coronavirus 2 and human papilloma virus |
| CN116262779A (zh) * | 2021-12-14 | 2023-06-16 | 深圳先进技术研究院 | 一种单细胞筛选鉴定人乳头瘤病毒特异性tcr的方法 |
| CN117402232A (zh) * | 2022-05-10 | 2024-01-16 | 广州医科大学 | 抗原短肽用于筛选治疗与hpv相关的疾病的药物中的用途及其筛选的tcr |
| CN115286690B (zh) * | 2022-05-10 | 2023-06-20 | 广州医科大学 | 抗原短肽用于筛选治疗与hpv相关的疾病的药物中的用途及其筛选的tcr |
| JP2025531850A (ja) | 2022-09-08 | 2025-09-25 | ジュノー セラピューティクス インコーポレイテッド | Ｔ細胞療法および継続的または間欠的ｄｇｋ阻害剤投薬の組合せ |
| GB202311170D0 (en) * | 2023-07-20 | 2023-09-06 | Univ Oxford Innovation Ltd | Antigen binding polypeptides |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5714352A (en) | 1996-03-20 | 1998-02-03 | Xenotech Incorporated | Directed switch-mediated DNA recombination |
| JP2004511425A (ja) | 2000-02-08 | 2004-04-15 | ザ ペン ステート リサーチ ファウンデーション | 免疫療法に使用されるインターロイキン１３受容体サブユニットアルファー２ |
| US20070218080A1 (en) | 2006-03-14 | 2007-09-20 | Mackay Memorial Hospital | Peptide antigen of human papillomavirus type 16 and application thereof |
| AU2008304555A1 (en) * | 2007-09-25 | 2009-04-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modified T cell receptors and related materials and methods |
| EP2618835B1 (en) * | 2010-09-20 | 2017-07-05 | BioNTech Cell & Gene Therapies GmbH | Antigen-specific t cell receptors and t cell epitopes |
| TWI507413B (zh) | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
| EP2802356A1 (en) | 2012-01-13 | 2014-11-19 | Apo-T B.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| US20150175683A1 (en) | 2012-06-26 | 2015-06-25 | Apo-T B.V. | Binding molecules targeting pathogens |
| AU2014290288B2 (en) * | 2013-07-15 | 2018-03-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-human papillomavirus 16 E6 T cell receptors |
| GB201322430D0 (en) * | 2013-12-18 | 2014-02-05 | Immunocore Ltd | T cell receptors |
| US10202640B2 (en) * | 2014-05-07 | 2019-02-12 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing |
-
2015
- 2015-10-16 EP EP15190230.1A patent/EP3156067A1/en not_active Withdrawn
-
2016
- 2016-10-13 CN CN201680060361.2A patent/CN108135998B/zh not_active Expired - Fee Related
- 2016-10-13 WO PCT/EP2016/074612 patent/WO2017064198A1/en not_active Ceased
- 2016-10-13 AU AU2016336817A patent/AU2016336817C1/en not_active Ceased
- 2016-10-13 EP EP16781446.6A patent/EP3362090A1/en not_active Withdrawn
- 2016-10-13 CA CA3001395A patent/CA3001395A1/en active Pending
- 2016-10-13 JP JP2018519710A patent/JP7000315B2/ja not_active Expired - Fee Related
- 2016-10-13 US US15/768,740 patent/US11401316B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018535668A5 (OSRAM) | ||
| JP2016505635A5 (OSRAM) | ||
| JP6913032B2 (ja) | 共通ネオ抗原 | |
| CN105384825B (zh) | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 | |
| PH12019501241A1 (en) | Novel t cell receptors and immune therapy using the same | |
| US20220170097A1 (en) | Car t cell transcriptional atlas | |
| CA3045233A1 (en) | Novel t cell receptors and immune therapy using the same | |
| MX2023003463A (es) | Receptores de linfocitos t e inmunoterapias basadas en el uso de los mismos contra canceres positivos para prame. | |
| PH12020550600A1 (en) | Novel engineered t cell receptors and immune therapy using the same | |
| JP2019511222A5 (OSRAM) | ||
| JP2020500523A5 (OSRAM) | ||
| WO2018172533A3 (en) | T cell receptors and immune therapy using the same against prame positive cancers | |
| JP2018509163A5 (OSRAM) | ||
| FI3250592T3 (fi) | Transtyretiinin vastaisia vasta-aineita | |
| CN108299561A (zh) | 一种pd-1纳米抗体及其克隆表达方法与应用 | |
| Soong et al. | Direct T cell activation via CD40 ligand generates high avidity CD8+ T cells capable of breaking immunological tolerance for the control of tumors | |
| WO2021247534A2 (en) | Compositions and methods for treating merkel cell carcinoma (mcc) using hla class i specific epitopes | |
| JP2016520053A5 (OSRAM) | ||
| Ligtenberg et al. | Cripto-1 vaccination elicits protective immunity against metastatic melanoma | |
| JP2014139185A5 (OSRAM) | ||
| CN101643497A (zh) | Lmp2a蛋白来源的hla-a2限制性表位多肽及其用途 | |
| CN113754756B (zh) | 一种识别hla-a*02:01/e629-38的tcr及其应用 | |
| CN102250244A (zh) | 人源抗人催乳素受体抗体及其应用 | |
| EP3635098B1 (en) | T-cells modified to overexpress phf19 | |
| CN103524625B (zh) | 一种新型诱导抗体产生的方法 |