JP2018534956A - ポリマー電界紡糸塞栓形成デバイスおよび使用の方法 - Google Patents

ポリマー電界紡糸塞栓形成デバイスおよび使用の方法 Download PDF

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Publication number
JP2018534956A
JP2018534956A JP2018513546A JP2018513546A JP2018534956A JP 2018534956 A JP2018534956 A JP 2018534956A JP 2018513546 A JP2018513546 A JP 2018513546A JP 2018513546 A JP2018513546 A JP 2018513546A JP 2018534956 A JP2018534956 A JP 2018534956A
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Prior art keywords
embolic device
fiber
meter
twists
polymer
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Pending
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JP2018513546A
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English (en)
Japanese (ja)
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JP2018534956A5 (https=
Inventor
ジェド ジョンソン,
ジェド ジョンソン,
タイラー グロール,
タイラー グロール,
デヴァン オースト,
デヴァン オースト,
Original Assignee
イコナノ ベンチャー パートナーズ, エルエルシー
イコナノ ベンチャー パートナーズ, エルエルシー
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Publication of JP2018534956A publication Critical patent/JP2018534956A/ja
Publication of JP2018534956A5 publication Critical patent/JP2018534956A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00General methods for the manufacture of artificial filaments or the like
    • D01F1/02Addition of substances to the spinning solution or to the melt
    • D01F1/10Other agents for modifying properties
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/58Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00526Methods of manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/00898Material properties expandable upon contact with fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/00942Material properties hydrophilic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12063Details concerning the detachment of the occluding device from the introduction device electrolytically detachable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12068Details concerning the detachment of the occluding device from the introduction device detachable by heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3966Radiopaque markers visible in an X-ray image
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Textile Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Mechanical Engineering (AREA)
JP2018513546A 2015-09-10 2016-09-12 ポリマー電界紡糸塞栓形成デバイスおよび使用の方法 Pending JP2018534956A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562216553P 2015-09-10 2015-09-10
US62/216,553 2015-09-10
US201662324629P 2016-04-19 2016-04-19
US62/324,629 2016-04-19
PCT/US2016/051393 WO2017044982A1 (en) 2015-09-10 2016-09-12 Polymeric electrospun embolization device and methods of use

Publications (2)

Publication Number Publication Date
JP2018534956A true JP2018534956A (ja) 2018-11-29
JP2018534956A5 JP2018534956A5 (https=) 2021-04-08

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JP2018513546A Pending JP2018534956A (ja) 2015-09-10 2016-09-12 ポリマー電界紡糸塞栓形成デバイスおよび使用の方法

Country Status (5)

Country Link
US (2) US10335154B2 (https=)
EP (1) EP3346947A4 (https=)
JP (1) JP2018534956A (https=)
CN (1) CN108135686B (https=)
WO (1) WO2017044982A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2802482C (en) 2010-06-17 2017-06-06 Washington University Biomedical patches with aligned fibers
IN2015DN02299A (https=) 2012-09-21 2015-08-21 Univ Washington
US10925611B2 (en) 2015-01-20 2021-02-23 Neurogami Medical, Inc. Packaging for surgical implant
US10857012B2 (en) 2015-01-20 2020-12-08 Neurogami Medical, Inc. Vascular implant
JP6763864B2 (ja) 2015-01-20 2020-09-30 ニューロガミ メディカル インコーポレイテッド 頭蓋内動脈瘤の治療のためのマイクログラフトおよび使用方法
US10736730B2 (en) 2015-01-20 2020-08-11 Neurogami Medical, Inc. Vascular implant
US11484319B2 (en) 2015-01-20 2022-11-01 Neurogami Medical, Inc. Delivery system for micrograft for treating intracranial aneurysms
CN108135686B (zh) 2015-09-10 2021-06-04 纳米纤维解决方案股份有限公司 聚合物静电纺丝栓塞装置和使用方法
EP3370788A4 (en) * 2015-11-02 2019-07-31 Nanofiber Solutions, LLC ELECTRO-spun fibers with contrast agents and method for producing same
US10632228B2 (en) 2016-05-12 2020-04-28 Acera Surgical, Inc. Tissue substitute materials and methods for tissue repair
MX383306B (es) 2016-08-02 2025-03-13 Fitesa Germany Gmbh Sistema y proceso para preparar telas no tejidas de acido polilactico.
US11441251B2 (en) 2016-08-16 2022-09-13 Fitesa Germany Gmbh Nonwoven fabrics comprising polylactic acid having improved strength and toughness
CN109925018B (zh) * 2019-01-30 2021-03-23 张韬 瘤内栓塞用串联封堵链段及采用其的动脉瘤封堵系统
CA3227437A1 (en) 2021-07-29 2023-02-02 Acera Surgical, Inc. Particle-form hybrid-scale fiber matrix
US12201749B2 (en) 2021-07-29 2025-01-21 Acera Surgical, Inc. Combined macro and micro-porous hybrid-scale fiber matrix
WO2023039381A1 (en) 2021-09-07 2023-03-16 Acera Surgical, Inc. Materials and methods for nerve repair and regeneration

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759787A (ja) * 1993-01-15 1995-03-07 Target Therapeutics Inc 放射線不透過性繊維を含む血管閉塞具
JP2006506171A (ja) * 2002-11-15 2006-02-23 ボストン サイエンティフィック リミテッド ナノファイバでできた塞栓装置
JP2013541358A (ja) * 2010-09-08 2013-11-14 フェノックス ゲゼルシャフト ミット ベシュレンクテル ハフツング 動静脈奇形の領域における血流に影響を与えるインプラント
US20140079758A1 (en) * 2012-09-19 2014-03-20 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US20150173772A1 (en) * 2013-12-20 2015-06-25 Microvention, Inc. Device Delivery System
WO2015100238A1 (en) * 2013-12-27 2015-07-02 Neograft Technologies, Inc. Artificial graft devices and related systems and methods

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418235A (en) 1980-02-14 1983-11-29 Mobil Oil Corporation Hydrocarbon conversion with zeolite having enhanced catalytic activity
US4419235A (en) 1981-10-13 1983-12-06 Boris Sway Gravity fed water treatment apparatus
US6425893B1 (en) 1990-03-13 2002-07-30 The Regents Of The University Of California Method and apparatus for fast electrolytic detachment of an implant
US5108407A (en) * 1990-06-08 1992-04-28 Rush-Presbyterian St. Luke's Medical Center Method and apparatus for placement of an embolic coil
US5997829A (en) 1995-05-26 1999-12-07 Hitachi Chemical Company, Ltd. Environment purifying material
US6136015A (en) * 1998-08-25 2000-10-24 Micrus Corporation Vasoocclusive coil
US20060122691A1 (en) * 1998-12-03 2006-06-08 Jacob Richter Hybrid stent
US6280457B1 (en) 1999-06-04 2001-08-28 Scimed Life Systems, Inc. Polymer covered vaso-occlusive devices and methods of producing such devices
US6312421B1 (en) 1999-07-23 2001-11-06 Neurovasx, Inc. Aneurysm embolization material and device
DE10010840A1 (de) 1999-10-30 2001-09-20 Dendron Gmbh Vorrichtung zur Implantation von Occlusionswendeln
US6635082B1 (en) 2000-12-29 2003-10-21 Advanced Cardiovascular Systems Inc. Radiopaque stent
US20020128680A1 (en) * 2001-01-25 2002-09-12 Pavlovic Jennifer L. Distal protection device with electrospun polymer fiber matrix
AU2002340749A1 (en) * 2001-05-04 2002-11-18 Concentric Medical Coated combination vaso-occlusive device
US6685956B2 (en) 2001-05-16 2004-02-03 The Research Foundation At State University Of New York Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications
US20040225279A1 (en) * 2001-06-01 2004-11-11 Jean Raymond Detachable tip microcatheter for use of liquid embolic agents
GB0130608D0 (en) * 2001-12-21 2002-02-06 Psimedica Ltd Medical fibres and fabrics
US7608058B2 (en) * 2002-07-23 2009-10-27 Micrus Corporation Stretch resistant therapeutic device
JP2007508121A (ja) * 2003-10-14 2007-04-05 キューブ メディカル エーエス 血管形成術用バルーン
AU2004289362A1 (en) 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
EP1791590B1 (en) 2004-08-25 2015-07-15 Microvention, Inc. Thermal detachment system for implantable devices
AU2005333585B2 (en) 2004-10-06 2010-12-16 Research Foundation Of Suny High flux and low fouling filtration media
US7815661B2 (en) * 2005-01-25 2010-10-19 Tyco Healthcare Group, Lp Method and apparatus for implanting an occlusive structure
US20070100414A1 (en) 2005-11-02 2007-05-03 Cardiomind, Inc. Indirect-release electrolytic implant delivery systems
US20070142859A1 (en) * 2005-12-19 2007-06-21 Boston Scientific Scimed, Inc. Embolic coils
JP4828283B2 (ja) * 2006-03-30 2011-11-30 テルモ株式会社 無針注射器具
US20070255422A1 (en) * 2006-04-25 2007-11-01 Mei Wei Calcium phosphate polymer composite and method
ES2764436T3 (es) * 2006-10-12 2020-06-03 Bard Inc C R Estructura inflable con capa trenzada
US7993523B2 (en) 2007-03-06 2011-08-09 E. I. Du Pont De Nemours And Company Liquid filtration media
US20100070020A1 (en) * 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
US20090018643A1 (en) * 2007-06-11 2009-01-15 Nanovasc, Inc. Stents
WO2009086208A2 (en) 2007-12-21 2009-07-09 Microvention, Inc. Hydrogel filaments for biomedical uses
JP5610542B2 (ja) * 2008-04-21 2014-10-22 コヴィディエン リミテッド パートナーシップ ブレードボール塞栓装置および送達システム
US20090299448A1 (en) 2008-05-30 2009-12-03 Neurovasx, Inc. Aneurysm treatment system
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US20110046657A1 (en) * 2009-08-20 2011-02-24 Boston Scientific Scimed, Inc. Embolic Coil Introducer Catheter Locking Mechanisms
EP2503959A4 (en) * 2009-11-25 2014-07-09 Univ Drexel SMOOTH VESSEL PRODUCED IN A HYBRID PROCESS
US9139935B2 (en) * 2010-04-21 2015-09-22 Taipei Medical University Electrostatic-assisted fiber spinning method and production of highly aligned and packed hollow fiber assembly and membrane
CA2802482C (en) 2010-06-17 2017-06-06 Washington University Biomedical patches with aligned fibers
US9243353B2 (en) * 2011-01-26 2016-01-26 Asahi Kasei Fibers Corp. Stent grafts
WO2013025819A2 (en) 2011-08-16 2013-02-21 The University Of Kansas Fibrous tracheal patch
US8979968B2 (en) 2011-09-15 2015-03-17 Lawrence Livermore National Security, Llc Radiological/biological/aerosol removal system
WO2013106822A1 (en) 2012-01-12 2013-07-18 Johnson Jed K Nanofiber scaffolds for biological structures
WO2014004746A2 (en) 2012-06-26 2014-01-03 Harvard Bioscience, Inc. Methods and compositions for promoting the structural integrity of scaffolds for tissue engineering
US10080687B2 (en) 2012-09-21 2018-09-25 Washington University Biomedical patches with spatially arranged fibers
IN2015DN02299A (https=) 2012-09-21 2015-08-21 Univ Washington
JP6806442B2 (ja) * 2013-03-15 2021-01-06 エンボ・メディカル・リミテッド 塞栓形成システム
US11154302B2 (en) * 2014-03-31 2021-10-26 DePuy Synthes Products, Inc. Aneurysm occlusion device
JP7219428B2 (ja) 2015-04-29 2023-02-08 エヌエフエス アイピー ホールディングス、エルエルシー 多成分系電界紡糸繊維スキャフォールド
CN108135686B (zh) 2015-09-10 2021-06-04 纳米纤维解决方案股份有限公司 聚合物静电纺丝栓塞装置和使用方法
EP3777920A1 (en) 2015-11-30 2021-02-17 Toray Industries, Inc. Phosphorus adsorbent, porous fiber and phosphorus adsorption column
CN107019959A (zh) 2016-02-02 2017-08-08 江苏盛德信息科技有限公司 一种空气净化材料
US10632228B2 (en) 2016-05-12 2020-04-28 Acera Surgical, Inc. Tissue substitute materials and methods for tissue repair

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759787A (ja) * 1993-01-15 1995-03-07 Target Therapeutics Inc 放射線不透過性繊維を含む血管閉塞具
JP2006506171A (ja) * 2002-11-15 2006-02-23 ボストン サイエンティフィック リミテッド ナノファイバでできた塞栓装置
JP2013541358A (ja) * 2010-09-08 2013-11-14 フェノックス ゲゼルシャフト ミット ベシュレンクテル ハフツング 動静脈奇形の領域における血流に影響を与えるインプラント
US20140079758A1 (en) * 2012-09-19 2014-03-20 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US20150173772A1 (en) * 2013-12-20 2015-06-25 Microvention, Inc. Device Delivery System
WO2015100238A1 (en) * 2013-12-27 2015-07-02 Neograft Technologies, Inc. Artificial graft devices and related systems and methods

Also Published As

Publication number Publication date
EP3346947A4 (en) 2019-07-24
WO2017044982A1 (en) 2017-03-16
US20170071607A1 (en) 2017-03-16
US10335154B2 (en) 2019-07-02
EP3346947A1 (en) 2018-07-18
CN108135686B (zh) 2021-06-04
US11337705B2 (en) 2022-05-24
US20190374227A1 (en) 2019-12-12
CN108135686A (zh) 2018-06-08

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