JP2018534117A5 - - Google Patents
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- Publication number
- JP2018534117A5 JP2018534117A5 JP2018545682A JP2018545682A JP2018534117A5 JP 2018534117 A5 JP2018534117 A5 JP 2018534117A5 JP 2018545682 A JP2018545682 A JP 2018545682A JP 2018545682 A JP2018545682 A JP 2018545682A JP 2018534117 A5 JP2018534117 A5 JP 2018534117A5
- Authority
- JP
- Japan
- Prior art keywords
- dialysate
- mmol
- albumin
- ions
- bicarbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010088751 Albumins Proteins 0.000 claims 14
- 102000009027 Albumins Human genes 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 13
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 11
- 239000000872 buffer Substances 0.000 claims 9
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 8
- 239000011575 calcium Substances 0.000 claims 8
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 8
- 239000007983 Tris buffer Substances 0.000 claims 6
- 150000002500 ions Chemical class 0.000 claims 6
- 239000006172 buffering agent Substances 0.000 claims 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 4
- 239000001569 carbon dioxide Substances 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 4
- 208000010444 Acidosis Diseases 0.000 claims 3
- 206010027417 Metabolic acidosis Diseases 0.000 claims 3
- 208000003826 Respiratory Acidosis Diseases 0.000 claims 3
- 230000002378 acidificating effect Effects 0.000 claims 3
- 230000003139 buffering effect Effects 0.000 claims 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 2
- 206010019663 Hepatic failure Diseases 0.000 claims 2
- 108091006905 Human Serum Albumin Proteins 0.000 claims 2
- 102000008100 Human Serum Albumin Human genes 0.000 claims 2
- 208000001647 Renal Insufficiency Diseases 0.000 claims 2
- 229940098773 bovine serum albumin Drugs 0.000 claims 2
- 229910001424 calcium ion Inorganic materials 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 201000006370 kidney failure Diseases 0.000 claims 2
- 208000007903 liver failure Diseases 0.000 claims 2
- 231100000835 liver failure Toxicity 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 239000008363 phosphate buffer Substances 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 108700012359 toxins Proteins 0.000 claims 2
- 241001385733 Aesculus indica Species 0.000 claims 1
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000003463 adsorbent Substances 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims 1
- 238000006392 deoxygenation reaction Methods 0.000 claims 1
- 238000011026 diafiltration Methods 0.000 claims 1
- 238000000502 dialysis Methods 0.000 claims 1
- 239000000385 dialysis solution Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 238000004064 recycling Methods 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 238000004062 sedimentation Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2015/002330 WO2017084682A1 (en) | 2015-11-20 | 2015-11-20 | Method for extracorporeal carbon dioxide removal |
| EPPCT/EP2015/002330 | 2015-11-20 | ||
| PCT/EP2016/078197 WO2017085291A1 (en) | 2015-11-20 | 2016-11-18 | Method for extracorporeal carbon dioxide removal |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018534117A JP2018534117A (ja) | 2018-11-22 |
| JP2018534117A5 true JP2018534117A5 (https=) | 2019-12-26 |
| JP7013380B2 JP7013380B2 (ja) | 2022-01-31 |
Family
ID=54849586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545682A Active JP7013380B2 (ja) | 2015-11-20 | 2016-11-18 | 体外での二酸化炭素除去のための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20190015574A1 (https=) |
| EP (2) | EP3377141B1 (https=) |
| JP (1) | JP7013380B2 (https=) |
| KR (1) | KR102682273B1 (https=) |
| CN (1) | CN108289987B (https=) |
| AU (1) | AU2016356067B2 (https=) |
| BR (1) | BR112018006777A2 (https=) |
| CA (1) | CA3000925A1 (https=) |
| DK (1) | DK3377141T3 (https=) |
| ES (1) | ES2842473T3 (https=) |
| IL (1) | IL258477B (https=) |
| MX (1) | MX2018006081A (https=) |
| PL (1) | PL3377141T3 (https=) |
| WO (2) | WO2017084682A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| DK3429657T3 (da) | 2016-03-14 | 2022-06-13 | Advitos Gmbh | Systemer eller apparater til at udføre dialyse. |
| EP3634530B1 (en) * | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
| WO2019055933A2 (en) | 2017-09-17 | 2019-03-21 | Keller Steven Paul | SYSTEMS, DEVICES AND METHODS FOR EXTRACORPOREAL CARBON DIOXIDE REMOVAL |
| DE102017131192A1 (de) | 2017-12-22 | 2019-06-27 | Fresenius Medical Care Deutschland Gmbh | Pufferlösung zur Reduzierung des Kohlendioxidgehaltes in extrakorporalem Blut |
| JP7474715B2 (ja) * | 2018-06-27 | 2024-04-25 | ザ ジェニーヴァ ファウンデーション | 単一および多臓器不全の移動式治療のための装着可能モジュール式体外生命維持デバイス |
| EP3673929B1 (en) * | 2018-12-27 | 2023-09-27 | Gambro Lundia AB | Apparatus for extracorporeal blood treatment |
| DE102020104117A1 (de) * | 2020-02-18 | 2021-08-19 | Universität des Saarlandes | Vorrichtung zum Entfernen eines Gases aus einer wässrigen Flüssigkeit |
| CN111939354B (zh) * | 2020-07-30 | 2022-05-10 | 中国科学院生态环境研究中心 | 一种用于透析液再生的酸碱调节液和透析液再生方法 |
| CN116773294A (zh) * | 2023-05-24 | 2023-09-19 | 深圳市科曼医疗设备有限公司 | 去激素血清的制备方法、检测试剂盒 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4375414A (en) | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
| US3846236A (en) * | 1971-10-22 | 1974-11-05 | Wisconsin Alumni Res Found | Method and apparatus for dialysis |
| SE7403799L (https=) | 1974-03-21 | 1975-09-22 | Gambro Ab | |
| DE3230540A1 (de) | 1982-08-17 | 1984-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Verfahren und vorrichtung zur entfernung von protein- oder lipidgebundenen toxinen aus blut oder blutfraktionen |
| US4663049A (en) | 1984-07-05 | 1987-05-05 | University Of Utah | Process for therapeutic dissociation of immune complexes and removal of antigens |
| IT8504923V0 (it) | 1985-06-07 | 1985-06-07 | Miren Srl | Dispositivo per il controllo del bilancio idrico di un paziente durante il trattamento di emodialisi |
| FR2651438A1 (fr) | 1989-09-07 | 1991-03-08 | Fondation Nale Transfusion San | Procede d'inactivation par ultrasons d'agents infectieux ou parasitaires dans des milieux biologiques et applications du procede. |
| ATE105712T1 (de) * | 1990-01-12 | 1994-06-15 | Nephro Medica Pharma | Bicarbonat und calcium enthaltende infusions- und dialysierlösung. |
| US6344489B1 (en) | 1991-02-14 | 2002-02-05 | Wayne State University | Stabilized gas-enriched and gas-supersaturated liquids |
| DE4309410A1 (de) * | 1993-03-19 | 1995-02-16 | Stange Jan | Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials |
| US5753227A (en) | 1993-07-23 | 1998-05-19 | Strahilevitz; Meir | Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases |
| US5561115A (en) | 1994-08-10 | 1996-10-01 | Bayer Corporation | Low temperature albumin fractionation using sodium caprylate as a partitioning agent |
| US6607698B1 (en) | 1997-08-15 | 2003-08-19 | Therox, Inc. | Method for generalized extracorporeal support |
| US6264680B1 (en) | 1998-01-23 | 2001-07-24 | Viacirq, Inc. | Apparatuses and processes for whole-body hyperthermia |
| JP4061775B2 (ja) | 1998-05-21 | 2008-03-19 | ニプロ株式会社 | アルブミン含有腹膜透析液 |
| DE69929555T8 (de) | 1998-06-17 | 2007-05-31 | Nipro Corp. | Verwendung einer Flüssigkeit zur Herstellung einer Dialyselösung für die kontinuierliche rezirkulierende Peritonealdialyse |
| DE19831061A1 (de) | 1998-07-10 | 2000-01-13 | Rotkreuzstiftung Zentrallab | Herstellung von Proteinpräparationen mit verringertem Aggregatgehalt |
| US7670491B2 (en) | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| WO2000072658A1 (fr) | 1999-05-26 | 2000-12-07 | Sadykov Zharylkasyn Sarsenbeko | Procede de zharylkassyne permettant de recueillir des graines presentant un interet biologique, et dispositifs de mise en oeuvre de ce procede |
| DE60041588D1 (de) * | 1999-09-22 | 2009-04-02 | Advanced Renal Technologies | Anwendung eines dialysats mit hohem zitratgehalt |
| AU2001227865A1 (en) | 2000-01-11 | 2001-07-24 | Nephros, Inc. | Ionic enhanced dialysis/diafiltration system |
| CA2396853A1 (en) | 2000-01-11 | 2001-07-19 | Nephros, Inc. | Thermally enhanced dialysis/diafiltration system |
| JP2001226288A (ja) * | 2000-02-16 | 2001-08-21 | Terumo Corp | 腹膜劣化抑制剤および腹膜透析液 |
| CA2365787C (en) * | 2000-12-20 | 2006-02-14 | Dialysis Solutions Inc. | Sterile low bicarbonate dialysis concentrate solutions |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| EP1362605A1 (de) | 2002-05-14 | 2003-11-19 | Bernhard Dr. Kreymann | Dialysevorrichtung zur Entfernung proteingebundener Substanzen |
| US7455771B2 (en) | 2002-05-14 | 2008-11-25 | Hepa Wash Gmbh | Means for removing protein-bound substances |
| US7112273B2 (en) | 2002-09-27 | 2006-09-26 | Nxstage Medical, Inc. | Volumetric fluid balance control for extracorporeal blood treatment |
| US7686778B2 (en) | 2003-01-15 | 2010-03-30 | Nxstage Medical, Inc. | Waste balancing for extracorporeal blood treatment systems |
| ITMI20030212A1 (it) | 2003-02-07 | 2004-08-08 | Gambro Lundia Ab | Metodo per il trattamento extracorporeo di sangue |
| US7169303B2 (en) | 2003-05-28 | 2007-01-30 | Hemocleanse Technologies, Llc | Sorbent reactor for extracorporeal blood treatment systems, peritoneal dialysis systems, and other body fluid treatment systems |
| PL1691863T3 (pl) | 2003-10-13 | 2008-07-31 | Fresenius Medical Care Deutschland Gmbh | Urządzenie do realizacji terapii z dializą otrzewnową |
| JP4903583B2 (ja) | 2003-12-24 | 2012-03-28 | ケミカ テクノロジーズ， インコーポレイテッド | 携帯式個人透析用透析液再生システム |
| US7229967B2 (en) * | 2004-11-12 | 2007-06-12 | Hunter Research Corporation | Oxygenated albumin for use as blood and blood extender |
| JP4908044B2 (ja) | 2006-04-14 | 2012-04-04 | 株式会社ジェイ・エム・エス | 重量検出装置及びバランス制御装置 |
| WO2009071103A1 (en) | 2007-12-03 | 2009-06-11 | Hepa Wash Gmbh | Dialysate regeneration unit |
| DE102008015134A1 (de) | 2008-03-20 | 2009-10-01 | Gea Westfalia Separator Gmbh | Getriebeanordnung für eine Zentrifuge |
| DE102009008601A1 (de) * | 2009-02-12 | 2010-08-19 | Novalung Gmbh | Vorrichtung zur Behandlung einer biologischen Flüssigkeit |
| AU2010234206B2 (en) | 2009-04-06 | 2016-10-27 | Crearene Ag | Hemodialysis and peritoneal dialysis solutions comprising one or more creatine compounds |
| DK177144B1 (en) | 2009-06-19 | 2012-02-06 | Aquaporin As | A liquid membrane suitable for water extraction |
| DE102010023635A1 (de) | 2010-06-14 | 2011-12-15 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Fördern von Flüssigkeiten in die Behandlungseinheit einer medizinischen Behandlungsvorrichtung, insbesondere in den Dialysator einer Dialysevorrichtung |
| JP2012228285A (ja) | 2011-04-23 | 2012-11-22 | Sunceramics Corp | 酸素濃度を高めた透析液 |
| PL2644215T3 (pl) | 2012-03-28 | 2015-04-30 | Gambro Lundia Ab | Aparat do pozaustrojowej obróbki krwi |
| GB201207543D0 (en) | 2012-05-01 | 2012-06-13 | Haemair Ltd | Treatment of transfusion blood |
| WO2014028945A1 (en) * | 2012-08-17 | 2014-02-20 | The Regents Of The University Of California | Systems, methods and compositions for improved treatment of acidosis |
| CN102940886B (zh) | 2012-12-13 | 2015-02-18 | 鼎正动物药业（天津）有限公司 | 一种生物屏障渗透剂及其制备方法 |
| US10322221B2 (en) | 2013-01-18 | 2019-06-18 | University of Pittsburgh—of the Commonwealth System of Higher Education | Removal of carbon dioxide via dialysis |
| US20160022897A1 (en) | 2013-03-13 | 2016-01-28 | Nxstage Medical, Inc. | Single pass dialysis combined with multiple pass albumin dialysis |
| DE102013019356A1 (de) | 2013-11-19 | 2015-06-03 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Bilanzieren von Flüssigkeiten für eine extrakorporale Blutbehandlungsvorrichtung |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| EP3634530B1 (en) | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
-
2015
- 2015-11-20 WO PCT/EP2015/002330 patent/WO2017084682A1/en not_active Ceased
-
2016
- 2016-11-18 US US15/777,634 patent/US20190015574A1/en not_active Abandoned
- 2016-11-18 DK DK16798486.3T patent/DK3377141T3/da active
- 2016-11-18 CA CA3000925A patent/CA3000925A1/en active Pending
- 2016-11-18 JP JP2018545682A patent/JP7013380B2/ja active Active
- 2016-11-18 PL PL16798486T patent/PL3377141T3/pl unknown
- 2016-11-18 ES ES16798486T patent/ES2842473T3/es active Active
- 2016-11-18 KR KR1020187017413A patent/KR102682273B1/ko active Active
- 2016-11-18 EP EP16798486.3A patent/EP3377141B1/en active Active
- 2016-11-18 AU AU2016356067A patent/AU2016356067B2/en not_active Ceased
- 2016-11-18 WO PCT/EP2016/078197 patent/WO2017085291A1/en not_active Ceased
- 2016-11-18 MX MX2018006081A patent/MX2018006081A/es unknown
- 2016-11-18 EP EP20191518.8A patent/EP3795189A1/en not_active Withdrawn
- 2016-11-18 CN CN201680063826.XA patent/CN108289987B/zh active Active
- 2016-11-18 BR BR112018006777A patent/BR112018006777A2/pt not_active Application Discontinuation
-
2018
- 2018-04-01 IL IL258477A patent/IL258477B/en active IP Right Grant
-
2022
- 2022-04-27 US US17/730,828 patent/US11833282B2/en active Active
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