JP2018538118A5 - - Google Patents
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- Publication number
- JP2018538118A5 JP2018538118A5 JP2018545683A JP2018545683A JP2018538118A5 JP 2018538118 A5 JP2018538118 A5 JP 2018538118A5 JP 2018545683 A JP2018545683 A JP 2018545683A JP 2018545683 A JP2018545683 A JP 2018545683A JP 2018538118 A5 JP2018538118 A5 JP 2018538118A5
- Authority
- JP
- Japan
- Prior art keywords
- dialysate
- oxygen
- blood
- albumin
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 23
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 20
- 229910052760 oxygen Inorganic materials 0.000 claims 20
- 239000001301 oxygen Substances 0.000 claims 20
- 210000004369 blood Anatomy 0.000 claims 16
- 239000008280 blood Substances 0.000 claims 16
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 10
- 108010088751 Albumins Proteins 0.000 claims 9
- 102000009027 Albumins Human genes 0.000 claims 9
- 239000012528 membrane Substances 0.000 claims 6
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 5
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 5
- 239000001569 carbon dioxide Substances 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 5
- 239000011575 calcium Substances 0.000 claims 4
- 150000002500 ions Chemical class 0.000 claims 4
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 208000010444 Acidosis Diseases 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 206010027417 Metabolic acidosis Diseases 0.000 claims 2
- 208000001647 Renal Insufficiency Diseases 0.000 claims 2
- 208000003826 Respiratory Acidosis Diseases 0.000 claims 2
- 239000007983 Tris buffer Substances 0.000 claims 2
- 230000002378 acidificating effect Effects 0.000 claims 2
- 210000001367 artery Anatomy 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 2
- 230000003139 buffering effect Effects 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 238000000502 dialysis Methods 0.000 claims 2
- -1 hydrogen cations Chemical class 0.000 claims 2
- 201000006370 kidney failure Diseases 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 230000001706 oxygenating effect Effects 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 210000003462 vein Anatomy 0.000 claims 2
- XOHUEYCVLUUEJJ-UHFFFAOYSA-N 2,3-Bisphosphoglyceric acid Chemical compound OP(=O)(O)OC(C(=O)O)COP(O)(O)=O XOHUEYCVLUUEJJ-UHFFFAOYSA-N 0.000 claims 1
- XOHUEYCVLUUEJJ-UHFFFAOYSA-I 2,3-Diphosphoglycerate Chemical compound [O-]P(=O)([O-])OC(C(=O)[O-])COP([O-])([O-])=O XOHUEYCVLUUEJJ-UHFFFAOYSA-I 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 108010064719 Oxyhemoglobins Proteins 0.000 claims 1
- 239000003463 adsorbent Substances 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 229910001424 calcium ion Inorganic materials 0.000 claims 1
- 238000006392 deoxygenation reaction Methods 0.000 claims 1
- 239000000385 dialysis solution Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2015/002331 | 2015-11-20 | ||
| PCT/EP2015/002331 WO2017084683A1 (en) | 2015-11-20 | 2015-11-20 | Method for extracorporeal lung support |
| PCT/EP2016/078198 WO2017085292A1 (en) | 2015-11-20 | 2016-11-18 | Method for extracorporeal lung support |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018538118A JP2018538118A (ja) | 2018-12-27 |
| JP2018538118A5 true JP2018538118A5 (https=) | 2019-12-26 |
| JP6983793B2 JP6983793B2 (ja) | 2021-12-17 |
Family
ID=54608483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545683A Active JP6983793B2 (ja) | 2015-11-20 | 2016-11-18 | 体外での肺補助のための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11583620B2 (https=) |
| EP (2) | EP4011416A1 (https=) |
| JP (1) | JP6983793B2 (https=) |
| KR (1) | KR102837618B1 (https=) |
| CN (1) | CN108367109B (https=) |
| AU (1) | AU2016356068B2 (https=) |
| BR (1) | BR112018007200A2 (https=) |
| CA (1) | CA3000927A1 (https=) |
| DK (1) | DK3377139T3 (https=) |
| ES (1) | ES2905621T3 (https=) |
| IL (1) | IL258481B (https=) |
| MX (1) | MX2018006089A (https=) |
| PL (1) | PL3377139T3 (https=) |
| WO (2) | WO2017084683A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| DK3429657T3 (da) | 2016-03-14 | 2022-06-13 | Advitos Gmbh | Systemer eller apparater til at udføre dialyse. |
| EP3634530B1 (en) * | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
| WO2019055933A2 (en) | 2017-09-17 | 2019-03-21 | Keller Steven Paul | SYSTEMS, DEVICES AND METHODS FOR EXTRACORPOREAL CARBON DIOXIDE REMOVAL |
| CN108211032B (zh) | 2018-02-01 | 2023-11-17 | 南方医科大学珠江医院 | 组合型生物人工肝支持系统 |
| JP7301509B2 (ja) * | 2018-09-06 | 2023-07-03 | 聡 安斎 | 治療装置 |
| WO2020154638A1 (en) | 2019-01-25 | 2020-07-30 | Transonic Systems, Inc. | Method and apparatus for assessing cardiac output in veno-venous extracorporeal blood oxygenation |
| US11633525B2 (en) | 2019-01-29 | 2023-04-25 | Transonic Systems Inc. | Method and apparatus for assessing cardiac output in veno-arterial extracorporeal blood oxygenation |
| IL285848B2 (en) * | 2019-02-26 | 2024-10-01 | Digital Blood Corp | System for non-invasive examination of blood environment parameters |
| US20220031921A1 (en) * | 2019-04-29 | 2022-02-03 | Verthermia Acquisition, Inc. | Method and System for Controlled Hyperthermia |
| US11065379B2 (en) * | 2019-04-30 | 2021-07-20 | Veryhermia Acquistion, Inc. | Method and system for controlled hyperthermia |
| JP7347857B2 (ja) * | 2019-05-02 | 2023-09-20 | トランソニック システムズ インク | 静脈－静脈体外血液酸素化を受けている患者の心拍出量の計算 |
| DE102019007144A1 (de) * | 2019-10-15 | 2021-04-15 | ProMedTec Germany GmbH | Verfahren und Anordnung zur Verbesserung des Austausches von Gasen über semipermeable Membranen im wässrigen Milieu |
| DE102020104117A1 (de) * | 2020-02-18 | 2021-08-19 | Universität des Saarlandes | Vorrichtung zum Entfernen eines Gases aus einer wässrigen Flüssigkeit |
| CN115916283B (zh) * | 2020-04-07 | 2026-01-16 | Gis风险投资公司 | 将溶解氧输注到静脉内流体中以为受损患者或创伤患者提供静脉血液的短期紧急充氧 |
| EP4251227A4 (en) * | 2020-12-01 | 2024-07-10 | Boundless Science, LLC | Method and apparatus for enhanced transport |
| US11219551B1 (en) * | 2021-04-25 | 2022-01-11 | Verthermia Acquisition, Inc. | Method and system for controlled hyperthermia |
| WO2024024459A1 (ja) * | 2022-07-28 | 2024-02-01 | 国立大学法人 東京大学 | 血漿交換システム、及び血漿交換システムの制御方法 |
| JP2024064862A (ja) * | 2022-10-28 | 2024-05-14 | 株式会社ジェイ・エム・エス | 血液浄化システム及び中間システム |
Family Cites Families (52)
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| US4375414A (en) | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
| US3771658A (en) * | 1971-10-20 | 1973-11-13 | R Brumfield | Blood transport membrane pump |
| US3846236A (en) * | 1971-10-22 | 1974-11-05 | Wisconsin Alumni Res Found | Method and apparatus for dialysis |
| SE7403799L (https=) | 1974-03-21 | 1975-09-22 | Gambro Ab | |
| DE3230540A1 (de) | 1982-08-17 | 1984-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Verfahren und vorrichtung zur entfernung von protein- oder lipidgebundenen toxinen aus blut oder blutfraktionen |
| US4663049A (en) | 1984-07-05 | 1987-05-05 | University Of Utah | Process for therapeutic dissociation of immune complexes and removal of antigens |
| IT8504923V0 (it) | 1985-06-07 | 1985-06-07 | Miren Srl | Dispositivo per il controllo del bilancio idrico di un paziente durante il trattamento di emodialisi |
| FR2651438A1 (fr) | 1989-09-07 | 1991-03-08 | Fondation Nale Transfusion San | Procede d'inactivation par ultrasons d'agents infectieux ou parasitaires dans des milieux biologiques et applications du procede. |
| US6344489B1 (en) | 1991-02-14 | 2002-02-05 | Wayne State University | Stabilized gas-enriched and gas-supersaturated liquids |
| DE4309410A1 (de) | 1993-03-19 | 1995-02-16 | Stange Jan | Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials |
| US5753227A (en) | 1993-07-23 | 1998-05-19 | Strahilevitz; Meir | Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases |
| US5561115A (en) | 1994-08-10 | 1996-10-01 | Bayer Corporation | Low temperature albumin fractionation using sodium caprylate as a partitioning agent |
| US6607698B1 (en) * | 1997-08-15 | 2003-08-19 | Therox, Inc. | Method for generalized extracorporeal support |
| US6264680B1 (en) | 1998-01-23 | 2001-07-24 | Viacirq, Inc. | Apparatuses and processes for whole-body hyperthermia |
| JP4061775B2 (ja) | 1998-05-21 | 2008-03-19 | ニプロ株式会社 | アルブミン含有腹膜透析液 |
| JP2000072658A (ja) | 1998-06-17 | 2000-03-07 | Nissho Corp | 腹膜透析液および腹膜透析法 |
| DE69929555T8 (de) | 1998-06-17 | 2007-05-31 | Nipro Corp. | Verwendung einer Flüssigkeit zur Herstellung einer Dialyselösung für die kontinuierliche rezirkulierende Peritonealdialyse |
| DE19831061A1 (de) | 1998-07-10 | 2000-01-13 | Rotkreuzstiftung Zentrallab | Herstellung von Proteinpräparationen mit verringertem Aggregatgehalt |
| US7670491B2 (en) | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| AU2001227865A1 (en) | 2000-01-11 | 2001-07-24 | Nephros, Inc. | Ionic enhanced dialysis/diafiltration system |
| CA2396853A1 (en) | 2000-01-11 | 2001-07-19 | Nephros, Inc. | Thermally enhanced dialysis/diafiltration system |
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| FR2873925B1 (fr) * | 2004-08-05 | 2006-10-13 | Erytech Pharma Soc Par Actions | Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes |
| EP1649883A1 (en) | 2004-10-19 | 2006-04-26 | MRI S.r.l. Società Unipersonale | A CO2 removal device for removing carbon dioxide from blood or from a fluid taken from patient's cardio-circulatory system |
| JP4908044B2 (ja) | 2006-04-14 | 2012-04-04 | 株式会社ジェイ・エム・エス | 重量検出装置及びバランス制御装置 |
| US20090018484A1 (en) * | 2007-07-11 | 2009-01-15 | Levitov Alexander B | System device and method for oxygenation |
| WO2009071103A1 (en) | 2007-12-03 | 2009-06-11 | Hepa Wash Gmbh | Dialysate regeneration unit |
| DE102009008601A1 (de) * | 2009-02-12 | 2010-08-19 | Novalung Gmbh | Vorrichtung zur Behandlung einer biologischen Flüssigkeit |
| AU2010234206B2 (en) | 2009-04-06 | 2016-10-27 | Crearene Ag | Hemodialysis and peritoneal dialysis solutions comprising one or more creatine compounds |
| DK177144B1 (en) * | 2009-06-19 | 2012-02-06 | Aquaporin As | A liquid membrane suitable for water extraction |
| CN102107031A (zh) * | 2009-12-28 | 2011-06-29 | 天津市海河医院 | 血液血浆中毒素滤过吸附器及其制备方法和应用 |
| DE102010023635A1 (de) | 2010-06-14 | 2011-12-15 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Fördern von Flüssigkeiten in die Behandlungseinheit einer medizinischen Behandlungsvorrichtung, insbesondere in den Dialysator einer Dialysevorrichtung |
| JP2012228285A (ja) | 2011-04-23 | 2012-11-22 | Sunceramics Corp | 酸素濃度を高めた透析液 |
| PL2644215T3 (pl) | 2012-03-28 | 2015-04-30 | Gambro Lundia Ab | Aparat do pozaustrojowej obróbki krwi |
| EP2653178A1 (de) | 2012-04-16 | 2013-10-23 | Zentrum für biomedizinische Technologie der Donau- Universität Krems | Sicherheitseinrichtung für eine extrakorporale Blutbehandlung |
| GB201207543D0 (en) * | 2012-05-01 | 2012-06-13 | Haemair Ltd | Treatment of transfusion blood |
| CN102940886B (zh) | 2012-12-13 | 2015-02-18 | 鼎正动物药业（天津）有限公司 | 一种生物屏障渗透剂及其制备方法 |
| US10322221B2 (en) | 2013-01-18 | 2019-06-18 | University of Pittsburgh—of the Commonwealth System of Higher Education | Removal of carbon dioxide via dialysis |
| US20160022897A1 (en) | 2013-03-13 | 2016-01-28 | Nxstage Medical, Inc. | Single pass dialysis combined with multiple pass albumin dialysis |
| DE102013019356A1 (de) | 2013-11-19 | 2015-06-03 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Bilanzieren von Flüssigkeiten für eine extrakorporale Blutbehandlungsvorrichtung |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| EP3634530B1 (en) | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
-
2015
- 2015-11-20 WO PCT/EP2015/002331 patent/WO2017084683A1/en not_active Ceased
-
2016
- 2016-11-18 BR BR112018007200A patent/BR112018007200A2/pt not_active Application Discontinuation
- 2016-11-18 WO PCT/EP2016/078198 patent/WO2017085292A1/en not_active Ceased
- 2016-11-18 EP EP21207826.5A patent/EP4011416A1/en not_active Withdrawn
- 2016-11-18 EP EP16797952.5A patent/EP3377139B1/en active Active
- 2016-11-18 PL PL16797952T patent/PL3377139T3/pl unknown
- 2016-11-18 JP JP2018545683A patent/JP6983793B2/ja active Active
- 2016-11-18 MX MX2018006089A patent/MX2018006089A/es unknown
- 2016-11-18 ES ES16797952T patent/ES2905621T3/es active Active
- 2016-11-18 CN CN201680063827.4A patent/CN108367109B/zh active Active
- 2016-11-18 DK DK16797952.5T patent/DK3377139T3/da active
- 2016-11-18 KR KR1020187017421A patent/KR102837618B1/ko active Active
- 2016-11-18 US US15/777,639 patent/US11583620B2/en active Active
- 2016-11-18 CA CA3000927A patent/CA3000927A1/en active Pending
- 2016-11-18 AU AU2016356068A patent/AU2016356068B2/en not_active Ceased
-
2018
- 2018-04-02 IL IL258481A patent/IL258481B/en unknown
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