BR112018006777A2 - método para a extração extracorporeal de dióxido de carbono - Google Patents

método para a extração extracorporeal de dióxido de carbono

Info

Publication number
BR112018006777A2
BR112018006777A2 BR112018006777A BR112018006777A BR112018006777A2 BR 112018006777 A2 BR112018006777 A2 BR 112018006777A2 BR 112018006777 A BR112018006777 A BR 112018006777A BR 112018006777 A BR112018006777 A BR 112018006777A BR 112018006777 A2 BR112018006777 A2 BR 112018006777A2
Authority
BR
Brazil
Prior art keywords
present
blood
dialysis
dialysis fluid
malfunction
Prior art date
Application number
BR112018006777A
Other languages
English (en)
Inventor
Kreymann Bernhard
Hüsstege Christoph
Original Assignee
Hepa Wash Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hepa Wash Gmbh filed Critical Hepa Wash Gmbh
Publication of BR112018006777A2 publication Critical patent/BR112018006777A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1676Dialysates therefor containing proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • A61M1/166Heating
    • A61M1/1664Heating with temperature control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1694Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
    • A61M1/1696Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698Blood oxygenators with or without heat-exchangers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0225Carbon oxides, e.g. Carbon dioxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/202Blood composition characteristics partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/208Blood composition characteristics pH-value

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a presente invenção refere-se a um processo adequado para o suporte pulmonar extracorpóreo. o processo depende da exposição ao sangue, separado por meio de uma membrana semipermeável do líquido de diálise. o líquido de diálise da presente invenção compreende um agente tampão e tem uma capacidade de armazenamento elevado para os íons de h+. os carbonatos de dióxido de carbono, bicarbonato e hidrogênio podem ser transportados de maneira eficaz através de uma membrana semipermeável para o líquido de diálise. a presente invenção também permite a regeneração e reciclagem do líquido de diálise e, portanto, para sua reciclagem e uso repetido. a versatilidade do líquido de diálise permite ajustar o ph do líquido de diálise, adicionar fluidos ao líquido de diálise e/ou ao sangue no circuito extracorpóreo e remover as substâncias do sangue no circuito extracorpóreo, dependendo das condições e necessidades. dessa maneira, a presente invenção é versátil e adequada para tratar ou prevenir acidose respiratória, acidose metabólica, doenças associadas a mau funcionamento do pulmão e/ou mau funcionamento renal e/ou mau funcionamento do fígado. por exemplo, quando a função renal é limitada, o equilíbrio ácido-base do sangue pode ser proporcionado por meio do método da presente invenção; e quando a função hepática é limitada, as toxinas podem ser removidas do sangue por meio do método da presente invenção.
BR112018006777A 2015-11-20 2016-11-18 método para a extração extracorporeal de dióxido de carbono BR112018006777A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2015/002330 WO2017084682A1 (en) 2015-11-20 2015-11-20 Method for extracorporeal carbon dioxide removal
PCT/EP2016/078197 WO2017085291A1 (en) 2015-11-20 2016-11-18 Method for extracorporeal carbon dioxide removal

Publications (1)

Publication Number Publication Date
BR112018006777A2 true BR112018006777A2 (pt) 2018-10-09

Family

ID=54849586

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018006777A BR112018006777A2 (pt) 2015-11-20 2016-11-18 método para a extração extracorporeal de dióxido de carbono

Country Status (14)

Country Link
US (2) US20190015574A1 (pt)
EP (2) EP3377141B1 (pt)
JP (1) JP7013380B2 (pt)
KR (1) KR102682273B1 (pt)
CN (1) CN108289987B (pt)
AU (1) AU2016356067B2 (pt)
BR (1) BR112018006777A2 (pt)
CA (1) CA3000925A1 (pt)
DK (1) DK3377141T3 (pt)
ES (1) ES2842473T3 (pt)
IL (1) IL258477B (pt)
MX (1) MX2018006081A (pt)
PL (1) PL3377141T3 (pt)
WO (2) WO2017084682A1 (pt)

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WO2017084682A1 (en) 2015-11-20 2017-05-26 Hepa Wash Gmbh Method for extracorporeal carbon dioxide removal
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Also Published As

Publication number Publication date
CN108289987B (zh) 2024-08-27
AU2016356067A1 (en) 2018-04-12
US20220249753A1 (en) 2022-08-11
PL3377141T3 (pl) 2021-05-31
MX2018006081A (es) 2018-11-09
EP3377141A1 (en) 2018-09-26
AU2016356067B2 (en) 2021-05-20
US20190015574A1 (en) 2019-01-17
EP3377141B1 (en) 2020-10-21
DK3377141T3 (da) 2020-12-14
US11833282B2 (en) 2023-12-05
CA3000925A1 (en) 2017-05-26
KR102682273B1 (ko) 2024-07-04
ES2842473T3 (es) 2021-07-14
IL258477A (en) 2018-06-28
EP3795189A1 (en) 2021-03-24
JP7013380B2 (ja) 2022-01-31
WO2017084682A1 (en) 2017-05-26
CN108289987A (zh) 2018-07-17
IL258477B (en) 2021-05-31
KR20180085762A (ko) 2018-07-27
WO2017085291A1 (en) 2017-05-26
JP2018534117A (ja) 2018-11-22

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