|
US1013219A
(en)
|
1910-04-26 |
1912-01-02 |
Rex Aerial Navigating And Construction Company |
Aerial vehicle.
|
|
US6140466A
(en)
|
1994-01-18 |
2000-10-31 |
The Scripps Research Institute |
Zinc finger protein derivatives and methods therefor
|
|
US6242568B1
(en)
|
1994-01-18 |
2001-06-05 |
The Scripps Research Institute |
Zinc finger protein derivatives and methods therefor
|
|
EP0770129B1
(en)
|
1994-01-18 |
2005-11-23 |
The Scripps Research Institute |
Zinc finger protein derivatives and methods therefor
|
|
GB9824544D0
(en)
|
1998-11-09 |
1999-01-06 |
Medical Res Council |
Screening system
|
|
CA2196419C
(en)
|
1994-08-20 |
2007-08-21 |
Yen Choo |
Improvements in or relating to binding proteins for recognition of dna
|
|
US5789538A
(en)
|
1995-02-03 |
1998-08-04 |
Massachusetts Institute Of Technology |
Zinc finger proteins with high affinity new DNA binding specificities
|
|
US5925523A
(en)
|
1996-08-23 |
1999-07-20 |
President & Fellows Of Harvard College |
Intraction trap assay, reagents and uses thereof
|
|
GB2338237B
(en)
|
1997-02-18 |
2001-02-28 |
Actinova Ltd |
In vitro peptide or protein expression library
|
|
GB9703369D0
(en)
|
1997-02-18 |
1997-04-09 |
Lindqvist Bjorn H |
Process
|
|
GB9710809D0
(en)
|
1997-05-23 |
1997-07-23 |
Medical Res Council |
Nucleic acid binding proteins
|
|
GB9710807D0
(en)
|
1997-05-23 |
1997-07-23 |
Medical Res Council |
Nucleic acid binding proteins
|
|
US6410248B1
(en)
|
1998-01-30 |
2002-06-25 |
Massachusetts Institute Of Technology |
General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
|
|
AU746454B2
(en)
|
1998-03-02 |
2002-05-02 |
Massachusetts Institute Of Technology |
Poly zinc finger proteins with improved linkers
|
|
US6140081A
(en)
|
1998-10-16 |
2000-10-31 |
The Scripps Research Institute |
Zinc finger binding domains for GNN
|
|
US6453242B1
(en)
|
1999-01-12 |
2002-09-17 |
Sangamo Biosciences, Inc. |
Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
|
|
US7013219B2
(en)
|
1999-01-12 |
2006-03-14 |
Sangamo Biosciences, Inc. |
Regulation of endogenous gene expression in cells using zinc finger proteins
|
|
US6599692B1
(en)
|
1999-09-14 |
2003-07-29 |
Sangamo Bioscience, Inc. |
Functional genomics using zinc finger proteins
|
|
US6534261B1
(en)
|
1999-01-12 |
2003-03-18 |
Sangamo Biosciences, Inc. |
Regulation of endogenous gene expression in cells using zinc finger proteins
|
|
US6794136B1
(en)
|
2000-11-20 |
2004-09-21 |
Sangamo Biosciences, Inc. |
Iterative optimization in the design of binding proteins
|
|
HK1049515B
(en)
|
1999-12-06 |
2006-01-13 |
Sangamo Biosciences Inc. |
Methods of using randomized libraries of zinc finger proteins for the identification of gene function
|
|
DE60143192D1
(de)
|
2000-02-08 |
2010-11-18 |
Sangamo Biosciences Inc |
Zellen zur entdeckung von medikamenten
|
|
US20020061512A1
(en)
|
2000-02-18 |
2002-05-23 |
Kim Jin-Soo |
Zinc finger domains and methods of identifying same
|
|
US20030044787A1
(en)
|
2000-05-16 |
2003-03-06 |
Joung J. Keith |
Methods and compositions for interaction trap assays
|
|
JP2002060786A
(ja)
|
2000-08-23 |
2002-02-26 |
Kao Corp |
硬質表面用殺菌防汚剤
|
|
US7067317B2
(en)
|
2000-12-07 |
2006-06-27 |
Sangamo Biosciences, Inc. |
Regulation of angiogenesis with zinc finger proteins
|
|
GB0108491D0
(en)
|
2001-04-04 |
2001-05-23 |
Gendaq Ltd |
Engineering zinc fingers
|
|
WO2003016496A2
(en)
|
2001-08-20 |
2003-02-27 |
The Scripps Research Institute |
Zinc finger binding domains for cnn
|
|
US7262054B2
(en)
|
2002-01-22 |
2007-08-28 |
Sangamo Biosciences, Inc. |
Zinc finger proteins for DNA binding and gene regulation in plants
|
|
AU2003251286B2
(en)
|
2002-01-23 |
2007-08-16 |
The University Of Utah Research Foundation |
Targeted chromosomal mutagenesis using zinc finger nucleases
|
|
US20030232410A1
(en)
|
2002-03-21 |
2003-12-18 |
Monika Liljedahl |
Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
|
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
|
CN101824090B
(zh)
|
2002-06-14 |
2013-01-02 |
免疫医疗公司 |
人源化单克隆抗体hPAM4
|
|
JP2006502748A
(ja)
|
2002-09-05 |
2006-01-26 |
カリフォルニア インスティテュート オブ テクノロジー |
遺伝子ターゲッティングを誘発するキメラヌクレアーゼの使用方法
|
|
EP1578797A1
(en)
|
2002-12-13 |
2005-09-28 |
Licentia Ltd. |
The transmembrane protein amigo and uses thereof
|
|
US8409861B2
(en)
|
2003-08-08 |
2013-04-02 |
Sangamo Biosciences, Inc. |
Targeted deletion of cellular DNA sequences
|
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
|
EP2292274A1
(en)
|
2004-09-16 |
2011-03-09 |
Sangamo BioSciences, Inc. |
Compositions and methods for protein production
|
|
MX2007013757A
(es)
|
2005-05-05 |
2008-01-24 |
Univ Arizona |
Reagrupacion permitida de secuencia (seer)-met odo de novedad para visualizar secuencias de adn especificas.
|
|
JP5266210B2
(ja)
|
2006-05-25 |
2013-08-21 |
サンガモ バイオサイエンシズ インコーポレイテッド |
改変開裂ハーフドメイン
|
|
ES2465996T3
(es)
|
2006-05-25 |
2014-06-09 |
Sangamo Biosciences, Inc. |
Métodos y composiciones para la inactivación genética
|
|
CA2684378C
(en)
|
2007-04-26 |
2016-11-29 |
Sangamo Biosciences, Inc. |
Targeted integration into the ppp1r12c locus
|
|
EP2167523B1
(en)
|
2007-06-19 |
2014-07-23 |
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College |
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger rna cap
|
|
US8563314B2
(en)
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
|
JP2011518555A
(ja)
|
2008-04-14 |
2011-06-30 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
標的組込みのための線形ドナーコンストラクト
|
|
AU2009283194B2
(en)
|
2008-08-22 |
2014-10-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for targeted single-stranded cleavage and targeted integration
|
|
AU2009322964B2
(en)
|
2008-12-04 |
2014-10-09 |
Sangamo Therapeutics, Inc. |
Genome editing in rats using zinc-finger nucleases
|
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
|
EP3165234B1
(de)
|
2009-07-31 |
2019-04-03 |
ethris GmbH |
Rna mit einer kombination aus unmodifizierten und modifizierten nucleotiden zur proteinexpression
|
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
|
WO2011097036A1
(en)
|
2010-02-08 |
2011-08-11 |
Sangamo Biosciences, Inc. |
Engineered cleavage half-domains
|
|
JP2013518602A
(ja)
|
2010-02-09 |
2013-05-23 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
部分的に一本鎖のドナー分子による標的化ゲノム改変
|
|
US9567573B2
(en)
|
2010-04-26 |
2017-02-14 |
Sangamo Biosciences, Inc. |
Genome editing of a Rosa locus using nucleases
|
|
EP3156062A1
(en)
|
2010-05-17 |
2017-04-19 |
Sangamo BioSciences, Inc. |
Novel dna-binding proteins and uses thereof
|
|
CA3157027A1
(en)
|
2010-07-21 |
2012-01-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of a t-cell receptor gene
|
|
KR101930711B1
(ko)
|
2010-10-12 |
2018-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
혈우병 b의 치료를 위한 방법 및 조성물
|
|
CN107828820B
(zh)
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
US9150847B2
(en)
|
2011-09-21 |
2015-10-06 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of transgene expression
|
|
US8895264B2
(en)
|
2011-10-27 |
2014-11-25 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the HPRT locus
|
|
HK1200871A1
(en)
|
2011-11-16 |
2015-08-14 |
Sangamo Therapeutics, Inc. |
Modified dna-binding proteins and uses thereof
|
|
WO2013158309A2
(en)
*
|
2012-04-18 |
2013-10-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Non-disruptive gene targeting
|
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
|
EP3763810A3
(en)
|
2012-10-10 |
2021-07-14 |
Sangamo Therapeutics, Inc. |
T cell modifying compounds and uses thereof
|
|
WO2014059115A1
(en)
*
|
2012-10-10 |
2014-04-17 |
University Of Washington Through Its Center For Commercialization |
Compositions and methods for diagnosis and treatment of neurological disease
|
|
US9255250B2
(en)
|
2012-12-05 |
2016-02-09 |
Sangamo Bioscience, Inc. |
Isolated mouse or human cell having an exogenous transgene in an endogenous albumin gene
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
WO2014165506A1
(en)
*
|
2013-04-01 |
2014-10-09 |
Immunomedics, Inc. |
Anti-mucin antibodies for early detection and treament of pancreatic cancer
|
|
EP3730615A3
(en)
|
2013-05-15 |
2020-12-09 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treatment of a genetic condition
|
|
CA2926078C
(en)
|
2013-10-17 |
2021-11-16 |
Sangamo Biosciences, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
|
|
ES2813367T3
(es)
|
2013-12-09 |
2021-03-23 |
Sangamo Therapeutics Inc |
Métodos y composiciones para ingeniería genómica
|
|
CN106413760B
(zh)
|
2014-05-08 |
2020-01-14 |
桑格摩生物科学股份有限公司 |
用于治疗亨廷顿病的方法和组合物
|
|
US9816074B2
(en)
|
2014-07-25 |
2017-11-14 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
|
|
US9616090B2
(en)
|
2014-07-30 |
2017-04-11 |
Sangamo Biosciences, Inc. |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
|
|
US10179918B2
(en)
|
2015-05-07 |
2019-01-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for increasing transgene activity
|