JP2018533629A - 眼障害を治療するためのプロテアソーム阻害剤の使用 - Google Patents

眼障害を治療するためのプロテアソーム阻害剤の使用 Download PDF

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Publication number
JP2018533629A
JP2018533629A JP2018544025A JP2018544025A JP2018533629A JP 2018533629 A JP2018533629 A JP 2018533629A JP 2018544025 A JP2018544025 A JP 2018544025A JP 2018544025 A JP2018544025 A JP 2018544025A JP 2018533629 A JP2018533629 A JP 2018533629A
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eye
group
groups
composition
agents
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JP2018544025A
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English (en)
Japanese (ja)
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JP2018533629A5 (enExample
Inventor
クーロン、リック
Original Assignee
アキュイティス ファーマシューティカルズ、インコーポレイテッド
アキュイティス ファーマシューティカルズ、インコーポレイテッド
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Publication of JP2018533629A publication Critical patent/JP2018533629A/ja
Publication of JP2018533629A5 publication Critical patent/JP2018533629A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018544025A 2015-11-06 2016-10-24 眼障害を治療するためのプロテアソーム阻害剤の使用 Pending JP2018533629A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562251937P 2015-11-06 2015-11-06
US62/251,937 2015-11-06
PCT/US2016/058402 WO2017078953A1 (en) 2015-11-06 2016-10-24 Use of proteasome inhibitors to treat ocular disorders

Publications (2)

Publication Number Publication Date
JP2018533629A true JP2018533629A (ja) 2018-11-15
JP2018533629A5 JP2018533629A5 (enExample) 2019-12-05

Family

ID=58662653

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018544025A Pending JP2018533629A (ja) 2015-11-06 2016-10-24 眼障害を治療するためのプロテアソーム阻害剤の使用

Country Status (8)

Country Link
US (1) US20180325854A1 (enExample)
EP (1) EP3370709A4 (enExample)
JP (1) JP2018533629A (enExample)
CN (1) CN108883081A (enExample)
AU (1) AU2016349833A1 (enExample)
CA (1) CA3004587A1 (enExample)
IL (1) IL259153A (enExample)
WO (1) WO2017078953A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11478499B2 (en) 2018-01-30 2022-10-25 Universiteit Gent Compositions for use to treat cataract
US11278493B2 (en) * 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
CN110840860B (zh) * 2019-11-22 2021-12-31 国家纳米科学中心 一种纳米药物及其制备方法和应用
US20230050398A1 (en) * 2021-08-04 2023-02-16 Harrow Ip, Llc Methods for increasing shelf-life of ophthalmic pharmaceutical compositions
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11511199A (ja) * 1996-04-19 1999-09-28 トランジションズ・オプティカル・インコーポレイテッド 改良された疲労抵抗性のホトクロミックナフトピラン組成物
JP2002510627A (ja) * 1998-04-02 2002-04-09 ノバルティス アクチエンゲゼルシャフト 抗酸化剤の特別な使用により医薬組成物を安定化するための方法
JP2008521928A (ja) * 2004-12-03 2008-06-26 ダナ ファーバー キャンサー インスティテュート 腫瘍性疾患を治療するための組成物及び方法
JP2008540682A (ja) * 2005-05-20 2008-11-20 ジャック アービサー プロテアソーム阻害剤及びその使用法
JP2009512723A (ja) * 2005-10-24 2009-03-26 チバ ホールディング インコーポレーテッド 易酸化性薬剤の保護
WO2009145356A1 (en) * 2008-05-30 2009-12-03 Santen Pharmaceutical Co., Ltd. Method and composition for treating ocular hypertension and glaucoma
JP2010504984A (ja) * 2006-09-29 2010-02-18 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 目のアレルギーの処置に使用される方法および眼用装置
EP2883544A1 (en) * 2012-08-08 2015-06-17 Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory Composition used for improving macular pigment density in eyes and preventing or treating age-related macular degeneration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2456990C2 (ru) * 2006-09-15 2012-07-27 Янссен Фармацевтика Нв Комбинации специфичных ингибиторов гистоновых деацетилаз класса i с ингибиторами протеасом

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11511199A (ja) * 1996-04-19 1999-09-28 トランジションズ・オプティカル・インコーポレイテッド 改良された疲労抵抗性のホトクロミックナフトピラン組成物
JP2002510627A (ja) * 1998-04-02 2002-04-09 ノバルティス アクチエンゲゼルシャフト 抗酸化剤の特別な使用により医薬組成物を安定化するための方法
JP2008521928A (ja) * 2004-12-03 2008-06-26 ダナ ファーバー キャンサー インスティテュート 腫瘍性疾患を治療するための組成物及び方法
JP2008540682A (ja) * 2005-05-20 2008-11-20 ジャック アービサー プロテアソーム阻害剤及びその使用法
JP2009512723A (ja) * 2005-10-24 2009-03-26 チバ ホールディング インコーポレーテッド 易酸化性薬剤の保護
JP2010504984A (ja) * 2006-09-29 2010-02-18 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 目のアレルギーの処置に使用される方法および眼用装置
WO2009145356A1 (en) * 2008-05-30 2009-12-03 Santen Pharmaceutical Co., Ltd. Method and composition for treating ocular hypertension and glaucoma
JP2011521943A (ja) * 2008-05-30 2011-07-28 参天製薬株式会社 高眼圧症及び緑内障を治療するための方法及び組成物
EP2883544A1 (en) * 2012-08-08 2015-06-17 Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory Composition used for improving macular pigment density in eyes and preventing or treating age-related macular degeneration

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 40(2), JPN6020031609, 1999, pages 477 - 486, ISSN: 0004332632 *
JOURNAL OF DRUGS IN DERMATOLOGY, vol. 6(3), JPN6020031611, 2007, pages 352 - 355, ISSN: 0004332634 *
MEDIATORS OF INFLAMMATION, JPN6020031608, 2015, pages 1 - 10, ISSN: 0004332631 *
MOLECULAR VISION, vol. 20, JPN6020031610, 2014, pages 153 - 162, ISSN: 0004332633 *

Also Published As

Publication number Publication date
AU2016349833A1 (en) 2018-05-24
CN108883081A (zh) 2018-11-23
EP3370709A1 (en) 2018-09-12
IL259153A (en) 2018-06-28
US20180325854A1 (en) 2018-11-15
EP3370709A4 (en) 2019-12-18
WO2017078953A1 (en) 2017-05-11
CA3004587A1 (en) 2017-05-11

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