IL259153A - Use of proteasome inhibitors to treat ocular disorders - Google Patents

Use of proteasome inhibitors to treat ocular disorders

Info

Publication number
IL259153A
IL259153A IL259153A IL25915318A IL259153A IL 259153 A IL259153 A IL 259153A IL 259153 A IL259153 A IL 259153A IL 25915318 A IL25915318 A IL 25915318A IL 259153 A IL259153 A IL 259153A
Authority
IL
Israel
Prior art keywords
proteasome inhibitors
ocular disorders
treat ocular
treat
disorders
Prior art date
Application number
IL259153A
Other languages
English (en)
Hebrew (he)
Original Assignee
Accuitis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accuitis Pharmaceuticals Inc filed Critical Accuitis Pharmaceuticals Inc
Publication of IL259153A publication Critical patent/IL259153A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL259153A 2015-11-06 2018-05-06 Use of proteasome inhibitors to treat ocular disorders IL259153A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562251937P 2015-11-06 2015-11-06
PCT/US2016/058402 WO2017078953A1 (en) 2015-11-06 2016-10-24 Use of proteasome inhibitors to treat ocular disorders

Publications (1)

Publication Number Publication Date
IL259153A true IL259153A (en) 2018-06-28

Family

ID=58662653

Family Applications (1)

Application Number Title Priority Date Filing Date
IL259153A IL259153A (en) 2015-11-06 2018-05-06 Use of proteasome inhibitors to treat ocular disorders

Country Status (8)

Country Link
US (1) US20180325854A1 (enExample)
EP (1) EP3370709A4 (enExample)
JP (1) JP2018533629A (enExample)
CN (1) CN108883081A (enExample)
AU (1) AU2016349833A1 (enExample)
CA (1) CA3004587A1 (enExample)
IL (1) IL259153A (enExample)
WO (1) WO2017078953A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11478499B2 (en) 2018-01-30 2022-10-25 Universiteit Gent Compositions for use to treat cataract
US11278493B2 (en) * 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
CN110840860B (zh) * 2019-11-22 2021-12-31 国家纳米科学中心 一种纳米药物及其制备方法和应用
US20230050398A1 (en) * 2021-08-04 2023-02-16 Harrow Ip, Llc Methods for increasing shelf-life of ophthalmic pharmaceutical compositions
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770115A (en) * 1996-04-19 1998-06-23 Ppg Industries, Inc. Photochromic naphthopyran compositions of improved fatigue resistance
ID26033A (id) * 1998-04-02 2000-11-16 Novartis Ag Metode penstabilan komposisi bahan farmasi dengan penggunaan khusus dari antioksidan
SG157365A1 (en) * 2004-12-03 2009-12-29 Dana Farber Cancer Inst Inc Compositions and methods for treating neoplastic diseases
CA2609213C (en) * 2005-05-20 2016-08-23 Jack Arbiser Use of cinnamates to inhibit proteasome activity
AU2006308040A1 (en) * 2005-10-24 2007-05-03 Basf Se Protection of oxidizable agents
RU2456990C2 (ru) * 2006-09-15 2012-07-27 Янссен Фармацевтика Нв Комбинации специфичных ингибиторов гистоновых деацетилаз класса i с ингибиторами протеасом
CA2664790C (en) * 2006-09-29 2015-11-24 Johnson & Johnson Vision Care, Inc. Methods and ophthalmic devices used in the treatment of ocular allergies
EP2127638A1 (en) * 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
CN103566049B (zh) * 2012-08-08 2017-08-04 浙江医药股份有限公司新昌制药厂 用于提高眼睛中视黄斑色素密度并预防或治疗年龄相关性视黄斑衰退症的组合物

Also Published As

Publication number Publication date
AU2016349833A1 (en) 2018-05-24
CN108883081A (zh) 2018-11-23
EP3370709A1 (en) 2018-09-12
JP2018533629A (ja) 2018-11-15
US20180325854A1 (en) 2018-11-15
EP3370709A4 (en) 2019-12-18
WO2017078953A1 (en) 2017-05-11
CA3004587A1 (en) 2017-05-11

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