JP2018533608A5 - - Google Patents
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- JP2018533608A5 JP2018533608A5 JP2018524495A JP2018524495A JP2018533608A5 JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5 JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5
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- Prior art keywords
- cancer
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- 239000013078 crystal Substances 0.000 claims description 16
- -1 carrier Substances 0.000 claims description 15
- 238000000634 powder X-ray diffraction Methods 0.000 claims description 10
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| US10053465B2 (en) | 2015-08-26 | 2018-08-21 | Incyte Corporation | Pyrrolopyrimidine derivatives as TAM inhibitors |
| US10259805B2 (en) * | 2015-12-30 | 2019-04-16 | Synthon B.V. | Process for making crystalline form a of gefitinib |
| MX2018011792A (es) | 2016-03-28 | 2019-07-04 | Incyte Corp | Compuestos de pirrolotriazina como inhibidores de tyro3, axl y mer (tam). |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| EP3597636A4 (en) * | 2017-03-14 | 2020-10-21 | Allgenesis Biotherapeutics Inc. | CRYSTALLINE FORMS OF 3-Z- [1- (4- (N - ((4-METHYL-PIPERAZIN-1-YL) -METHYLCARBONYL) -N-METHYL-AMINO) -PHENYLAMINO) -1-PHENYL-METHYLENE] -6 -METHOXYCARBONYL-2-INDOLINONE |
| EP3687996B1 (en) | 2017-09-27 | 2021-11-03 | Incyte Corporation | Salts of pyrrolotriazine derivatives useful as tam inhibitors |
| DK3813800T3 (da) | 2018-06-29 | 2025-06-02 | Incyte Corp | Formuleringer af en axl/mer-hæmmer |
| PH12022552347A1 (en) | 2020-03-06 | 2024-01-29 | Incyte Corp | Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors |
| CN113512006B (zh) * | 2021-04-30 | 2025-01-28 | 瑞阳制药股份有限公司 | 达可替尼一水合物的晶型及其制备方法 |
| JP2025502748A (ja) | 2021-12-30 | 2025-01-28 | バイオメア フュージョン，インコーポレイテッド | Ｆｌｔ３の阻害剤としてのピラジン化合物 |
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| ES2599458T3 (es) * | 2008-10-14 | 2017-02-01 | Sunshine Lake Pharma Co., Ltd. | Compuestos y métodos de uso |
| EP2408300B1 (en) * | 2009-03-21 | 2016-05-11 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
| CA2820709C (en) | 2011-02-28 | 2016-02-16 | Sunshine Lake Pharma Co., Ltd. | Substituted quinoline compounds and methods of use |
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