JP2018533608A5 - - Google Patents
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- JP2018533608A5 JP2018533608A5 JP2018524495A JP2018524495A JP2018533608A5 JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5 JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5
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- Prior art keywords
- cancer
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- 239000013078 crystal Substances 0.000 claims description 16
- -1 carrier Substances 0.000 claims description 15
- 238000000634 powder X-ray diffraction Methods 0.000 claims description 10
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| WO2017027717A1 (en) | 2015-08-12 | 2017-02-16 | Incyte Corporation | Bicyclic fused pyrimidine compounds as tam inhibitors |
| WO2017035366A1 (en) | 2015-08-26 | 2017-03-02 | Incyte Corporation | Pyrrolopyrimidine derivatives as tam inhibitors |
| EP3397618B1 (en) * | 2015-12-30 | 2020-11-18 | Synthon B.V. | Process for making crystalline form a of gefitinib |
| AU2017241524B2 (en) | 2016-03-28 | 2021-07-08 | Incyte Corporation | Pyrrolotriazine compounds as TAM inhibitors |
| MX393780B (es) | 2017-01-17 | 2025-03-24 | Heparegenix Gmbh | Inhibidores de proteina cinasa para promover la regeneracion hepatica o reducir o prevenir la muerte de hepatocitos |
| EP3597636A4 (en) * | 2017-03-14 | 2020-10-21 | Allgenesis Biotherapeutics Inc. | CRYSTALLINE FORMS OF 3-Z- [1- (4- (N - ((4-METHYL-PIPERAZIN-1-YL) -METHYLCARBONYL) -N-METHYL-AMINO) -PHENYLAMINO) -1-PHENYL-METHYLENE] -6 -METHOXYCARBONYL-2-INDOLINONE |
| TWI821200B (zh) | 2017-09-27 | 2023-11-11 | 美商英塞特公司 | Tam抑制劑之鹽 |
| US11241438B2 (en) | 2018-06-29 | 2022-02-08 | Incyte Corporation | Formulations of an AXL/MER inhibitor |
| EP4114401A1 (en) | 2020-03-06 | 2023-01-11 | Incyte Corporation | Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors |
| CN113512006B (zh) * | 2021-04-30 | 2025-01-28 | 瑞阳制药股份有限公司 | 达可替尼一水合物的晶型及其制备方法 |
| JP2025502748A (ja) | 2021-12-30 | 2025-01-28 | バイオメア フュージョン，インコーポレイテッド | Ｆｌｔ３の阻害剤としてのピラジン化合物 |
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| AU2009303602B2 (en) * | 2008-10-14 | 2012-06-14 | Sunshine Lake Pharma Co., Ltd. | Compounds and methods of use |
| KR20110133048A (ko) * | 2009-03-21 | 2011-12-09 | 닝 시 | 아미노 에스테르 유도체, 그의 염 및 이용 방법 |
| MY181439A (en) | 2011-02-28 | 2020-12-22 | Sunshine Lake Pharma Co Ltd | Substituted quinoline compounds and methods of use |
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