JP2018533608A5 - - Google Patents
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- JP2018533608A5 JP2018533608A5 JP2018524495A JP2018524495A JP2018533608A5 JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5 JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018524495 A JP2018524495 A JP 2018524495A JP 2018533608 A5 JP2018533608 A5 JP 2018533608A5
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- Prior art keywords
- cancer
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- 239000013078 crystal Substances 0.000 claims description 16
- -1 carrier Substances 0.000 claims description 15
- 238000000634 powder X-ray diffraction Methods 0.000 claims description 10
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| US10053465B2 (en) | 2015-08-26 | 2018-08-21 | Incyte Corporation | Pyrrolopyrimidine derivatives as TAM inhibitors |
| WO2017114735A1 (en) * | 2015-12-30 | 2017-07-06 | Synthon B.V. | Process for making crystalline form a of gefitinib |
| CN114456176B (zh) | 2016-03-28 | 2024-08-30 | 因赛特公司 | 作为tam抑制剂的吡咯并三嗪化合物 |
| CN110291089B (zh) | 2017-01-17 | 2022-05-27 | 海帕瑞吉尼克斯股份有限公司 | 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂 |
| CN116063221A (zh) * | 2017-03-14 | 2023-05-05 | 新源生物科技股份有限公司 | 尼达尼布的晶型 |
| KR102739325B1 (ko) | 2017-09-27 | 2024-12-09 | 인사이트 코포레이션 | Tam 억제제로서 유용한 피롤로트리아진 유도체의 염 |
| US11241438B2 (en) | 2018-06-29 | 2022-02-08 | Incyte Corporation | Formulations of an AXL/MER inhibitor |
| PH12022552347A1 (en) | 2020-03-06 | 2024-01-29 | Incyte Corp | Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors |
| CN113512006B (zh) * | 2021-04-30 | 2025-01-28 | 瑞阳制药股份有限公司 | 达可替尼一水合物的晶型及其制备方法 |
| CA3242316A1 (en) | 2021-12-30 | 2023-07-06 | Biomea Fusion, Inc. | Pyrazine compounds as inhibitors of flt3 |
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| CA2740746A1 (en) * | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds comprising a spiro-ring and and methods of use |
| EP2408300B1 (en) * | 2009-03-21 | 2016-05-11 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
| RU2568258C2 (ru) * | 2011-02-28 | 2015-11-20 | Саншайн Лейк Фарма Ко., Лтд | Замещенные соединения хинолина и способы их использования |
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