ES2911678T3 - Forma cristalina de un compuesto de quinolina sustituida y composiciones farmacéuticas de la misma - Google Patents
Forma cristalina de un compuesto de quinolina sustituida y composiciones farmacéuticas de la misma Download PDFInfo
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- ES2911678T3 ES2911678T3 ES16865176T ES16865176T ES2911678T3 ES 2911678 T3 ES2911678 T3 ES 2911678T3 ES 16865176 T ES16865176 T ES 16865176T ES 16865176 T ES16865176 T ES 16865176T ES 2911678 T3 ES2911678 T3 ES 2911678T3
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- cancer
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- -1 quinoline compound Chemical class 0.000 title claims description 13
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- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims description 8
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- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims description 6
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims description 6
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims description 6
- 201000010099 disease Diseases 0.000 claims description 5
- 230000002062 proliferating effect Effects 0.000 claims description 5
- 229940124597 therapeutic agent Drugs 0.000 claims description 5
- 238000011282 treatment Methods 0.000 claims description 5
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Landscapes
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| US201562255391P | 2015-11-14 | 2015-11-14 | |
| PCT/US2016/061717 WO2017083788A1 (en) | 2015-11-14 | 2016-11-12 | Crystalline form of a substituted quinoline compound and pharmaceutical compositions thereof |
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| US9708333B2 (en) | 2015-08-12 | 2017-07-18 | Incyte Corporation | Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors |
| WO2017035366A1 (en) | 2015-08-26 | 2017-03-02 | Incyte Corporation | Pyrrolopyrimidine derivatives as tam inhibitors |
| US10259805B2 (en) * | 2015-12-30 | 2019-04-16 | Synthon B.V. | Process for making crystalline form a of gefitinib |
| PT3436461T (pt) | 2016-03-28 | 2024-01-23 | Incyte Corp | Compostos de pirrolotriazina como inibidores de tam |
| AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| WO2018165865A1 (zh) * | 2017-03-14 | 2018-09-20 | 新源生物科技股份有限公司 | 3-z-[1-(4-(n-((4-甲基-哌嗪-1-基)-甲羰基)-n-甲基-氨基)-苯氨基)-1-苯基-亚甲基]-6-甲氧羰基-2-吲哚满酮的晶型 |
| US10633387B2 (en) | 2017-09-27 | 2020-04-28 | Incyte Corporation | Salts of TAM inhibitors |
| SI3813800T1 (sl) | 2018-06-29 | 2025-07-31 | Incyte Corporation | Formulacije zaviralca axl/mer |
| JP2023516441A (ja) | 2020-03-06 | 2023-04-19 | インサイト・コーポレイション | Ａｘｌ／ｍｅｒ阻害剤及びｐｄ－１／ｐｄ－ｌ１阻害剤を含む併用療法 |
| CN113512006B (zh) * | 2021-04-30 | 2025-01-28 | 瑞阳制药股份有限公司 | 达可替尼一水合物的晶型及其制备方法 |
| PE20242008A1 (es) | 2021-12-30 | 2024-10-03 | Biomea Fusion Inc | Compuestos de pirazina como inhibidores de flt3 |
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| WO2010045095A1 (en) * | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds and methods of use |
| CA2752421C (en) * | 2009-03-21 | 2013-08-06 | Ning Xi | Amino ester derivatives, salts thereof and methods of use |
| WO2012118632A1 (en) * | 2011-02-28 | 2012-09-07 | Ning Xi | Substituted quinoline compounds and methods of use |
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| JP2018533608A (ja) | 2018-11-15 |
| EP3373932B1 (en) | 2022-03-30 |
| US20170313678A1 (en) | 2017-11-02 |
| US9920033B2 (en) | 2018-03-20 |
| WO2017083788A1 (en) | 2017-05-18 |
| EP3373932A1 (en) | 2018-09-19 |
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