JP2018538260A5 - - Google Patents
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- JP2018538260A5 JP2018538260A5 JP2018524313A JP2018524313A JP2018538260A5 JP 2018538260 A5 JP2018538260 A5 JP 2018538260A5 JP 2018524313 A JP2018524313 A JP 2018524313A JP 2018524313 A JP2018524313 A JP 2018524313A JP 2018538260 A5 JP2018538260 A5 JP 2018538260A5
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- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- crystalline form
- receptor tyrosine
- composition according
- Prior art date
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- -1 carrier Substances 0.000 claims description 16
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 10
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- 238000000634 powder X-ray diffraction Methods 0.000 claims description 8
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| US9840503B2 (en) | 2015-05-11 | 2017-12-12 | Incyte Corporation | Heterocyclic compounds and uses thereof |
| US9708333B2 (en) | 2015-08-12 | 2017-07-18 | Incyte Corporation | Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors |
| WO2017035366A1 (en) | 2015-08-26 | 2017-03-02 | Incyte Corporation | Pyrrolopyrimidine derivatives as tam inhibitors |
| IL261957B (en) | 2016-03-28 | 2022-07-01 | Incyte Corp | Pyrrolotriazine compounds as TAM inhibitors |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| JOP20200081A1 (ar) | 2017-09-27 | 2020-04-30 | Incyte Corp | أملاح من مشتقات بيرولوتريازين مفيدة بوصفها مثبطات لـ tam |
| DK3813800T3 (da) | 2018-06-29 | 2025-06-02 | Incyte Corp | Formuleringer af en axl/mer-hæmmer |
| MA55076A (fr) * | 2019-02-27 | 2022-04-20 | Astrazeneca Ab | Procédé de traitement d'une maladie ou d'un état fibrotique ou d'une pneumopathie interstitielle à l'aide d'un inhibiteur de la kinase src |
| CN115175904A (zh) * | 2019-12-20 | 2022-10-11 | Epizyme股份有限公司 | Ezh2抑制剂的结晶氢溴酸盐、其制备和用于治疗癌症的药物组合物 |
| WO2021178779A1 (en) | 2020-03-06 | 2021-09-10 | Incyte Corporation | Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors |
| AU2022426699A1 (en) | 2021-12-30 | 2024-07-11 | Biomea Fusion, Inc. | Pyrazine compounds as inhibitors of flt3 |
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| WO2010045095A1 (en) * | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds and methods of use |
| AU2010229147B2 (en) * | 2009-03-21 | 2012-07-05 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
| AU2012223639B2 (en) | 2011-02-28 | 2015-03-19 | Sunshine Lake Pharma Co., Ltd. | Substituted quinoline compounds and methods of use |
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