JP2018533355A5 - - Google Patents

Download PDF

Info

Publication number
JP2018533355A5
JP2018533355A5 JP2018509536A JP2018509536A JP2018533355A5 JP 2018533355 A5 JP2018533355 A5 JP 2018533355A5 JP 2018509536 A JP2018509536 A JP 2018509536A JP 2018509536 A JP2018509536 A JP 2018509536A JP 2018533355 A5 JP2018533355 A5 JP 2018533355A5
Authority
JP
Japan
Prior art keywords
chromatography
eluate
seq
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018509536A
Other languages
English (en)
Japanese (ja)
Other versions
JP7091238B2 (ja
JP2018533355A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/047912 external-priority patent/WO2017031476A2/en
Publication of JP2018533355A publication Critical patent/JP2018533355A/ja
Publication of JP2018533355A5 publication Critical patent/JP2018533355A5/ja
Priority to JP2022003518A priority Critical patent/JP2022062046A/ja
Application granted granted Critical
Publication of JP7091238B2 publication Critical patent/JP7091238B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018509536A 2015-08-20 2016-08-19 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用 Active JP7091238B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022003518A JP2022062046A (ja) 2015-08-20 2022-01-13 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562207910P 2015-08-20 2015-08-20
US201562207908P 2015-08-20 2015-08-20
US62/207,910 2015-08-20
US62/207,908 2015-08-20
US201562210378P 2015-08-26 2015-08-26
US62/210,378 2015-08-26
PCT/US2016/047912 WO2017031476A2 (en) 2015-08-20 2016-08-19 Purification of fkpa and uses thereof for producing recombinant polypeptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022003518A Division JP2022062046A (ja) 2015-08-20 2022-01-13 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用

Publications (3)

Publication Number Publication Date
JP2018533355A JP2018533355A (ja) 2018-11-15
JP2018533355A5 true JP2018533355A5 (https=) 2019-09-26
JP7091238B2 JP7091238B2 (ja) 2022-06-27

Family

ID=58052052

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018509536A Active JP7091238B2 (ja) 2015-08-20 2016-08-19 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用
JP2022003518A Pending JP2022062046A (ja) 2015-08-20 2022-01-13 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022003518A Pending JP2022062046A (ja) 2015-08-20 2022-01-13 Fkpaの精製、及び組換えポリペプチドの産生のためのその使用

Country Status (13)

Country Link
US (1) US20180327446A1 (https=)
EP (1) EP3337819B1 (https=)
JP (2) JP7091238B2 (https=)
KR (1) KR20180048731A (https=)
CN (1) CN108473558A (https=)
AU (1) AU2016308383A1 (https=)
BR (1) BR112018003127A2 (https=)
CA (1) CA2995385A1 (https=)
HK (1) HK1259368A1 (https=)
IL (2) IL257400A (https=)
MX (1) MX2018002068A (https=)
TW (1) TW201718623A (https=)
WO (1) WO2017031476A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
WO2019118921A1 (en) 2017-12-14 2019-06-20 Flodesign Sonics, Inc. Acoustic transducer drive and controller
CN111741770A (zh) 2017-12-29 2020-10-02 豪夫迈·罗氏有限公司 用于提供聚乙二醇化蛋白质组合物的方法
HRP20220041T1 (hr) * 2017-12-29 2022-04-15 F. Hoffmann - La Roche Ag Postupak za dobivanje pegiliranog proteinskog pripravka
MX2020008931A (es) * 2018-02-27 2020-10-01 Pfizer Purificacion de anticuerpos.
CA3094644A1 (en) * 2018-03-21 2019-09-26 Baxalta Incorporated Separation of vwf and vwf propeptide by chromatographic methods
WO2019193418A1 (en) 2018-04-05 2019-10-10 Bio-Rad Abd Serotec Gmbh Display systems for proteins of interest
AU2019348606A1 (en) * 2018-09-25 2021-04-15 Ichnos Sciences S.A. Antibody quantification in biological samples
CN114409798A (zh) * 2019-02-14 2022-04-29 美勒斯公司 制备包含两种或更多种抗体的组合物
US11674164B2 (en) 2019-03-18 2023-06-13 Bio-Rad Abd Serotec Gmbh Periplasmic fusion proteins
CN114981286B (zh) 2019-05-03 2026-02-13 豪夫迈·罗氏有限公司 降低从纯化平台获得的组合物中酶水解活性速率的方法
TW202138556A (zh) * 2019-12-20 2021-10-16 美商默沙東藥廠 經純化之腸病毒組合物及使用穀胱甘肽親和性層析之純化方法
AU2021208515A1 (en) 2020-01-15 2022-08-04 F. Hoffmann-La Roche Ag Methods to decrease impurities from recombinant protein manufacturing processes
WO2021168306A1 (en) * 2020-02-21 2021-08-26 Biogen Ma Inc. Methods of preparing oligonucleotide compositions using ultrafiltration / diafiltration
EP4118093A4 (en) * 2020-03-11 2024-04-17 Dr. Reddy's Laboratories Ltd. METHOD FOR PURIFYING A FC FUSION PROTEIN
EP4142792A4 (en) 2020-05-01 2024-11-27 Kashiv Biosciences, LLC An improved process of purification of protein
CA3233419A1 (en) * 2021-09-28 2023-04-06 Kashiv Biosciences, Llc An improved process for purification of protein
JP2024544607A (ja) * 2021-11-25 2024-12-03 エフ. ホフマン-ラ ロシュ アーゲー 少量の抗体副産物の定量

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002061090A2 (en) * 2000-12-14 2002-08-08 Genentech, Inc. Prokaryotically produced antibodies and uses thereof
SG10201608871XA (en) * 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
AU2009347206C1 (en) * 2008-10-20 2016-12-08 Abbvie Inc. Isolation and purification of antibodies using Protein A affinity chromatography
ES2813398T3 (es) * 2009-10-20 2021-03-23 Abbvie Inc Aislamiento y purificación de anticuerpos anti-IL-13 usando cromatografía de afinidad a Proteína A
US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
ES2690213T3 (es) * 2011-12-15 2018-11-19 Prestige Biopharma Pte. Ltd. Un método de purificación de anticuerpos
AR089529A1 (es) * 2011-12-30 2014-08-27 Abbvie Inc Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
AU2014205441B2 (en) * 2013-01-09 2019-12-12 Takeda Pharmaceutical Company Limited Methods for purification of arylsulfatase A
AR095774A1 (es) * 2013-04-05 2015-11-11 Genentech Inc Anticuerpos anti-il-4 y anticuerpos biespecíficos y sus usos
CA2909516C (en) * 2013-04-19 2023-03-07 Sutro Biopharma, Inc. Expression of biologically active proteins in a bacterial cell-free synthesis system using cell extracts with elevated levels of exogenous chaperones
CA2919174A1 (en) * 2013-08-19 2015-02-26 F. Hoffmann-La Roche Ag Separation of bispecific antibodies and bispecific antibody production side products using hydroxyapatite chromatography
EP4331605A3 (en) * 2013-09-13 2024-05-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
US20160272674A1 (en) * 2013-11-07 2016-09-22 Abbvie Inc. Isolation and purification of antibodies
JP2017507939A (ja) * 2014-02-21 2017-03-23 ジェネンテック, インコーポレイテッド 抗il−13/il−17二重特異性抗体及びその使用

Similar Documents

Publication Publication Date Title
JP2018533355A5 (https=)
US10919930B2 (en) Enhanced purification of antibodies and antibody fragments by apatite chromatography
JP5567691B2 (ja) Fc含有タンパク質を精製するためのクロマトグラフィー法
JP6285532B2 (ja) タンパク質aに基づくクロマトグラフィを使用するタンパク質純度を増加させる方法
US12528835B2 (en) Methods for enhanced removal of impurities during protein a chromatography
CN107793477A (zh) 蛋白质纯化
JP2020531557A (ja) タンパク質の精製方法
JP2012504586A (ja) 断片抗体のための精製方法
KR20230005847A (ko) 다가 면역글로불린 단일 가변 도메인의 생산 및 정제 방법
AU2012269240B2 (en) Single unit chromatography antibody purification
JP2023549938A (ja) タンパク質を精製するための緩衝液と方法
JP6861155B2 (ja) 酸性pH領域での抗体結合能が低下した抗体結合性タンパク質