JP2018531897A5 - - Google Patents
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- Publication number
- JP2018531897A5 JP2018531897A5 JP2018510377A JP2018510377A JP2018531897A5 JP 2018531897 A5 JP2018531897 A5 JP 2018531897A5 JP 2018510377 A JP2018510377 A JP 2018510377A JP 2018510377 A JP2018510377 A JP 2018510377A JP 2018531897 A5 JP2018531897 A5 JP 2018531897A5
- Authority
- JP
- Japan
- Prior art keywords
- carboxamide
- methoxy
- dodeca
- thia
- pentaene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(CC(C)(C1CCCCC1)C(*C1*2)C(*(*)*=C)=O)*1C1C2*CCC1 Chemical compound CC(CC(C)(C1CCCCC1)C(*C1*2)C(*(*)*=C)=O)*1C1C2*CCC1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562211118P | 2015-08-28 | 2015-08-28 | |
| US62/211,118 | 2015-08-28 | ||
| PCT/US2016/049112 WO2017040336A1 (en) | 2015-08-28 | 2016-08-26 | Probes for imaging huntingtin protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531897A JP2018531897A (ja) | 2018-11-01 |
| JP2018531897A5 true JP2018531897A5 (https=) | 2019-10-03 |
| JP6944929B2 JP6944929B2 (ja) | 2021-10-06 |
Family
ID=58103449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018510377A Active JP6944929B2 (ja) | 2015-08-28 | 2016-08-26 | ハンチントンタンパク質のイメージング用プローブ |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10137211B2 (https=) |
| EP (1) | EP3340796B1 (https=) |
| JP (1) | JP6944929B2 (https=) |
| CN (1) | CN108135172B (https=) |
| AU (1) | AU2016315648B2 (https=) |
| BR (1) | BR112018003331B1 (https=) |
| CA (1) | CA2995847C (https=) |
| DK (1) | DK3340796T3 (https=) |
| ES (1) | ES2885053T3 (https=) |
| HR (1) | HRP20211156T1 (https=) |
| HU (1) | HUE056509T2 (https=) |
| IL (1) | IL257537B (https=) |
| MX (1) | MX382156B (https=) |
| PL (1) | PL3340796T4 (https=) |
| PT (1) | PT3340796T (https=) |
| RU (1) | RU2721419C2 (https=) |
| SI (1) | SI3340796T1 (https=) |
| WO (1) | WO2017040336A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE056957T2 (hu) | 2014-08-29 | 2022-04-28 | Chdi Foundation Inc | Próbák huntingtin fehérjét megjelenítõ képalkotásra |
| AU2015308709B2 (en) | 2014-08-29 | 2020-01-02 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
| DK3197277T3 (da) | 2014-08-29 | 2022-01-31 | Chdi Foundation Inc | Prober til billeddannelse af huntingtin-protein |
| EP3186241B1 (en) | 2014-08-29 | 2020-10-07 | CHDI Foundation, Inc. | Probes for imaging huntington protein |
| PT3340796T (pt) | 2015-08-28 | 2021-07-28 | Chdi Foundation Inc | Sondas para imagens da proteína huntingtina |
| EP3749225A4 (en) * | 2018-02-08 | 2021-11-17 | Phraxis Inc. | ONE-PIECE ANASTOMOTIC CONNECTOR |
| JP7619952B2 (ja) | 2019-02-25 | 2025-01-22 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | 変異型ハンチンチンタンパク質を標的とするための化合物及びその使用 |
| WO2021252775A1 (en) * | 2020-06-11 | 2021-12-16 | Chdi Foundation, Inc. | Heterocyclic compounds and imaging agents for imaging huntingtin protein |
| CN117412960A (zh) * | 2021-04-08 | 2024-01-16 | Chdi基金会股份有限公司 | 用于对亨廷顿蛋白成像的异吲哚啉酮化合物和显像剂 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2126636T3 (es) | 1992-05-19 | 1999-04-01 | Adir | Derivados del bencimidazol con actividad antidiabetica y antiagregante plaquetaria. |
| AU2241400A (en) * | 1999-04-06 | 2000-10-12 | Yamanouchi Pharmaceutical Co., Ltd. | Novel thiazolobenzoimidazole derivative |
| JP2000351782A (ja) * | 1999-04-06 | 2000-12-19 | Yamanouchi Pharmaceut Co Ltd | メタボトロピックグルタメート受容体作用薬及び新規チアゾロベンゾイミダゾール誘導体 |
| UY27003A1 (es) | 2000-11-06 | 2002-07-31 | Schering Ag | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer |
| US20050192314A1 (en) * | 2003-11-13 | 2005-09-01 | Ambit Biosciences Corporation | Urea derivatives as C-kit modulators |
| TW200736252A (en) | 2006-01-27 | 2007-10-01 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| FR2919610B1 (fr) | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
| CA2731738A1 (en) * | 2008-07-24 | 2010-01-28 | Siemens Medical Solutions Usa, Inc. | Imaging agents useful for identifying ad pathology |
| EP2218464A1 (en) * | 2009-02-11 | 2010-08-18 | Technische Universität München | Compounds for non-invasive measurement of aggregates of amyloid peptides |
| CN103739605B (zh) * | 2009-03-23 | 2016-08-17 | 伊莱利利公司 | 用于检测神经障碍的显像剂 |
| WO2014011906A2 (en) | 2012-07-11 | 2014-01-16 | Nimbus Iris, Inc. | Irak inhibitors and uses thereof |
| US9902702B2 (en) * | 2014-07-15 | 2018-02-27 | Bristol-Myers Squibb Company | Spirocycloheptanes as inhibitors of rock |
| HUE056957T2 (hu) | 2014-08-29 | 2022-04-28 | Chdi Foundation Inc | Próbák huntingtin fehérjét megjelenítõ képalkotásra |
| EP3186241B1 (en) | 2014-08-29 | 2020-10-07 | CHDI Foundation, Inc. | Probes for imaging huntington protein |
| DK3197277T3 (da) | 2014-08-29 | 2022-01-31 | Chdi Foundation Inc | Prober til billeddannelse af huntingtin-protein |
| AU2015308709B2 (en) | 2014-08-29 | 2020-01-02 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
| PT3340796T (pt) | 2015-08-28 | 2021-07-28 | Chdi Foundation Inc | Sondas para imagens da proteína huntingtina |
-
2016
- 2016-08-26 PT PT168427151T patent/PT3340796T/pt unknown
- 2016-08-26 RU RU2018110055A patent/RU2721419C2/ru active
- 2016-08-26 JP JP2018510377A patent/JP6944929B2/ja active Active
- 2016-08-26 MX MX2018002338A patent/MX382156B/es unknown
- 2016-08-26 AU AU2016315648A patent/AU2016315648B2/en active Active
- 2016-08-26 CN CN201680059497.1A patent/CN108135172B/zh active Active
- 2016-08-26 DK DK16842715.1T patent/DK3340796T3/da active
- 2016-08-26 HR HRP20211156TT patent/HRP20211156T1/hr unknown
- 2016-08-26 ES ES16842715T patent/ES2885053T3/es active Active
- 2016-08-26 PL PL16842715T patent/PL3340796T4/pl unknown
- 2016-08-26 HU HUE16842715A patent/HUE056509T2/hu unknown
- 2016-08-26 CA CA2995847A patent/CA2995847C/en active Active
- 2016-08-26 SI SI201631285T patent/SI3340796T1/sl unknown
- 2016-08-26 EP EP16842715.1A patent/EP3340796B1/en active Active
- 2016-08-26 WO PCT/US2016/049112 patent/WO2017040336A1/en not_active Ceased
- 2016-08-26 BR BR112018003331-6A patent/BR112018003331B1/pt active IP Right Grant
- 2016-08-26 US US15/249,223 patent/US10137211B2/en active Active
-
2018
- 2018-02-14 IL IL257537A patent/IL257537B/en active IP Right Grant
- 2018-10-26 US US16/172,425 patent/US10765764B2/en active Active
-
2020
- 2020-08-06 US US16/987,277 patent/US11344637B2/en active Active
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