JP2018531046A5 - - Google Patents

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Publication number
JP2018531046A5
JP2018531046A5 JP2018539237A JP2018539237A JP2018531046A5 JP 2018531046 A5 JP2018531046 A5 JP 2018531046A5 JP 2018539237 A JP2018539237 A JP 2018539237A JP 2018539237 A JP2018539237 A JP 2018539237A JP 2018531046 A5 JP2018531046 A5 JP 2018531046A5
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JP
Japan
Prior art keywords
nucleic acid
inhibitor
seq
composition
based inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018539237A
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English (en)
Japanese (ja)
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JP2018531046A6 (ja
JP2018531046A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/057164 external-priority patent/WO2017066657A1/en
Publication of JP2018531046A publication Critical patent/JP2018531046A/ja
Publication of JP2018531046A6 publication Critical patent/JP2018531046A6/ja
Publication of JP2018531046A5 publication Critical patent/JP2018531046A5/ja
Pending legal-status Critical Current

Links

JP2018539237A 2015-10-14 2016-10-14 核酸ベースのtia−1阻害剤 Pending JP2018531046A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562241535P 2015-10-14 2015-10-14
US62/241,535 2015-10-14
US201662331795P 2016-05-04 2016-05-04
US62/331,795 2016-05-04
PCT/US2016/057164 WO2017066657A1 (en) 2015-10-14 2016-10-14 Nucleic acid based tia-1 inhibitors

Publications (3)

Publication Number Publication Date
JP2018531046A JP2018531046A (ja) 2018-10-25
JP2018531046A6 JP2018531046A6 (ja) 2018-12-13
JP2018531046A5 true JP2018531046A5 (https=) 2019-11-21

Family

ID=57209905

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018539237A Pending JP2018531046A (ja) 2015-10-14 2016-10-14 核酸ベースのtia−1阻害剤

Country Status (5)

Country Link
US (1) US20190142860A1 (https=)
EP (1) EP3362564B1 (https=)
JP (1) JP2018531046A (https=)
CA (1) CA3001853A1 (https=)
WO (1) WO2017066657A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019146805A1 (ja) * 2018-01-29 2019-08-01 国立大学法人東京医科歯科大学 前頭側頭葉変性症治療剤、前頭側頭葉変性症治療剤のスクリーニング方法、及び前頭側頭葉変性症の治療方法
CN113196055B (zh) * 2018-10-15 2025-06-27 马克斯·普朗克科学促进协会 用于治疗疾病的化合物及其筛选方法
JP2022512877A (ja) 2018-11-01 2022-02-07 エフ.ホフマン-ラ ロシュ アーゲー Tia1を標的とするアンチセンスオリゴヌクレオチド
CN111500694B (zh) * 2019-01-31 2023-02-24 中国科学院脑科学与智能技术卓越创新中心 Baz2b基因作为靶点在缓解衰老中的应用
EP3921650A1 (en) 2019-02-08 2021-12-15 Dewpoint Therapeutics, Inc. Methods of characterizing condensate-associated characteristics of compounds and uses thereof
JP2022547606A (ja) * 2019-09-16 2022-11-14 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Tia1を標的としたストレス顆粒形成およびタウ凝集を抑制する化合物の同定
CN114729941A (zh) 2019-09-18 2022-07-08 露点治疗公司 筛选凝聚物相关特异性的方法及其用途
CN113358617B (zh) * 2021-06-02 2024-03-01 重庆大学 胞外囊泡富集检测方法
WO2023129531A2 (en) * 2021-12-27 2023-07-06 Seq Biomarque, Llc. Methods for diagnosing and/or treating alzheimer's disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798245A (en) * 1993-10-07 1998-08-25 Dana-Farber Cancer Institute TIA-1 binding proteins and isolated complementary DNA encoding the same
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
US7217807B2 (en) * 2002-11-26 2007-05-15 Rosetta Genomics Ltd Bioinformatically detectable group of novel HIV regulatory genes and uses thereof
JP2014501097A (ja) * 2009-07-06 2014-01-20 アルナイラム ファーマシューティカルズ, インコーポレイテッド 生物由来物質の産生を高めるための組成物及び方法
CA2752947A1 (en) * 2011-06-30 2012-12-30 Benjamin J. Blencowe Foxp1 splice variants and methods and uses thereof

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