JP2018530766A5 - - Google Patents
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- JP2018530766A5 JP2018530766A5 JP2018537693A JP2018537693A JP2018530766A5 JP 2018530766 A5 JP2018530766 A5 JP 2018530766A5 JP 2018537693 A JP2018537693 A JP 2018537693A JP 2018537693 A JP2018537693 A JP 2018537693A JP 2018530766 A5 JP2018530766 A5 JP 2018530766A5
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- 102000004169 proteins and genes Human genes 0.000 description 53
- 108090000623 proteins and genes Proteins 0.000 description 53
- 238000000034 method Methods 0.000 description 26
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 22
- 210000003743 erythrocyte Anatomy 0.000 description 18
- 239000000523 sample Substances 0.000 description 18
- 201000010099 disease Diseases 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- 208000035475 disorder Diseases 0.000 description 8
- -1 cation salt Chemical class 0.000 description 7
- 239000012468 concentrated sample Substances 0.000 description 6
- 102100037850 Interferon gamma Human genes 0.000 description 4
- 108010074328 Interferon-gamma Proteins 0.000 description 4
- 108090001005 Interleukin-6 Proteins 0.000 description 4
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 description 3
- 102000003814 Interleukin-10 Human genes 0.000 description 3
- 108090000174 Interleukin-10 Proteins 0.000 description 3
- 108090000978 Interleukin-4 Proteins 0.000 description 3
- 102000004388 Interleukin-4 Human genes 0.000 description 3
- 108010002616 Interleukin-5 Proteins 0.000 description 3
- 102000000743 Interleukin-5 Human genes 0.000 description 3
- 108090001007 Interleukin-8 Proteins 0.000 description 3
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 3
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 3
- 210000000265 leukocyte Anatomy 0.000 description 3
- 210000002381 plasma Anatomy 0.000 description 3
- 108010065805 Interleukin-12 Proteins 0.000 description 2
- 102000013462 Interleukin-12 Human genes 0.000 description 2
- 108090000172 Interleukin-15 Proteins 0.000 description 2
- 108050003558 Interleukin-17 Proteins 0.000 description 2
- 102000013691 Interleukin-17 Human genes 0.000 description 2
- 108010002350 Interleukin-2 Proteins 0.000 description 2
- 201000011461 pre-eclampsia Diseases 0.000 description 2
- 108010081589 Becaplermin Proteins 0.000 description 1
- 102100021936 C-C motif chemokine 27 Human genes 0.000 description 1
- 101710112538 C-C motif chemokine 27 Proteins 0.000 description 1
- 102100025248 C-X-C motif chemokine 10 Human genes 0.000 description 1
- 101710098275 C-X-C motif chemokine 10 Proteins 0.000 description 1
- 102100036170 C-X-C motif chemokine 9 Human genes 0.000 description 1
- 101710085500 C-X-C motif chemokine 9 Proteins 0.000 description 1
- 108700012434 CCL3 Proteins 0.000 description 1
- 102000000013 Chemokine CCL3 Human genes 0.000 description 1
- 102000001326 Chemokine CCL4 Human genes 0.000 description 1
- 108010055165 Chemokine CCL4 Proteins 0.000 description 1
- 108010008951 Chemokine CXCL12 Proteins 0.000 description 1
- 102000006573 Chemokine CXCL12 Human genes 0.000 description 1
- 108010012236 Chemokines Proteins 0.000 description 1
- 102000019034 Chemokines Human genes 0.000 description 1
- 102100031051 Cysteine and glycine-rich protein 1 Human genes 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102100023688 Eotaxin Human genes 0.000 description 1
- 101710139422 Eotaxin Proteins 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 101150021185 FGF gene Proteins 0.000 description 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 description 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 description 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 description 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 description 1
- 102100021866 Hepatocyte growth factor Human genes 0.000 description 1
- 101000898034 Homo sapiens Hepatocyte growth factor Proteins 0.000 description 1
- 101001076408 Homo sapiens Interleukin-6 Proteins 0.000 description 1
- 101000868152 Homo sapiens Son of sevenless homolog 1 Proteins 0.000 description 1
- 101100369992 Homo sapiens TNFSF10 gene Proteins 0.000 description 1
- 108010002352 Interleukin-1 Proteins 0.000 description 1
- 102000014158 Interleukin-12 Subunit p40 Human genes 0.000 description 1
- 108010011429 Interleukin-12 Subunit p40 Proteins 0.000 description 1
- 108010002386 Interleukin-3 Proteins 0.000 description 1
- 108010002335 Interleukin-9 Proteins 0.000 description 1
- 102000000585 Interleukin-9 Human genes 0.000 description 1
- 102100032352 Leukemia inhibitory factor Human genes 0.000 description 1
- 108090000581 Leukemia inhibitory factor Proteins 0.000 description 1
- 102000004083 Lymphotoxin-alpha Human genes 0.000 description 1
- 108090000542 Lymphotoxin-alpha Proteins 0.000 description 1
- 108010046938 Macrophage Colony-Stimulating Factor Proteins 0.000 description 1
- 102000007651 Macrophage Colony-Stimulating Factor Human genes 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 102000046283 TNF-Related Apoptosis-Inducing Ligand Human genes 0.000 description 1
- 108700012411 TNFSF10 Proteins 0.000 description 1
- 102000040945 Transcription factor Human genes 0.000 description 1
- 108091023040 Transcription factor Proteins 0.000 description 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 description 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 description 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 1
- 108091006374 cAMP receptor proteins Proteins 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000004068 intracellular signaling Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015904075A AU2015904075A0 (en) | 2015-10-07 | Blood preparation and profiling | |
| AU2015904075 | 2015-10-07 | ||
| PCT/AU2016/000341 WO2017059477A1 (en) | 2015-10-07 | 2016-10-06 | Blood preparation and profiling |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021003537A Division JP2021073453A (ja) | 2015-10-07 | 2021-01-13 | 血液の調製及びプロファイリング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018530766A JP2018530766A (ja) | 2018-10-18 |
| JP2018530766A5 true JP2018530766A5 (enExample) | 2019-11-14 |
| JP6824994B2 JP6824994B2 (ja) | 2021-02-03 |
Family
ID=58487130
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018537693A Active JP6824994B2 (ja) | 2015-10-07 | 2016-10-06 | 血液の調製及びプロファイリング |
| JP2021003537A Pending JP2021073453A (ja) | 2015-10-07 | 2021-01-13 | 血液の調製及びプロファイリング |
| JP2023034247A Pending JP2023078210A (ja) | 2015-10-07 | 2023-03-07 | 血液の調製及びプロファイリング |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021003537A Pending JP2021073453A (ja) | 2015-10-07 | 2021-01-13 | 血液の調製及びプロファイリング |
| JP2023034247A Pending JP2023078210A (ja) | 2015-10-07 | 2023-03-07 | 血液の調製及びプロファイリング |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11243218B2 (enExample) |
| EP (2) | EP4009047A1 (enExample) |
| JP (3) | JP6824994B2 (enExample) |
| KR (1) | KR102632490B1 (enExample) |
| CN (2) | CN108700565B (enExample) |
| AU (1) | AU2016334875B2 (enExample) |
| CA (1) | CA3001154C (enExample) |
| HK (1) | HK1258470A1 (enExample) |
| SG (1) | SG11201802754XA (enExample) |
| WO (1) | WO2017059477A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3009369A1 (en) | 2015-12-22 | 2017-06-29 | Sangui Bio Pty. Ltd | Therapeutic methods using erythrocytes |
| WO2018112500A1 (en) * | 2016-12-20 | 2018-06-28 | Sangui Bio Pty. Ltd | Blood profiling with protease inhibitors |
| CN108715833B (zh) * | 2018-06-01 | 2021-09-14 | 天晴干细胞股份有限公司 | 一种负载血小板裂解液的微球制备方法 |
| US20240352423A1 (en) * | 2021-03-10 | 2024-10-24 | Terasaki Institute For Biomedical Innovation | Methods and systems of producing products such as animal derived products |
| CN114081899A (zh) * | 2021-11-02 | 2022-02-25 | 四川大学华西医院 | 一种富白细胞富血小板血浆的制备方法 |
| US20250085283A1 (en) | 2022-03-23 | 2025-03-13 | Teijin Limited | Method for quantifying nicotinamide adenine dinucleotide (nad+) or nicotinamide mononucleotide (nmn), and kit and filter paper for performing the method |
| WO2024010763A1 (en) * | 2022-07-07 | 2024-01-11 | Russell Biotech, Inc. | Preparation of platelet free mononuclear cells |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4931276A (en) | 1987-10-30 | 1990-06-05 | Franco Robert S | Method for introducing desired agents into red blood cells |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| WO1992005801A1 (en) | 1990-10-04 | 1992-04-16 | University Of Virginia Alumni Patents Foundation | Primate erythrocyte bound monoclonal antibody heteropolymers |
| ES2167391T3 (es) * | 1994-09-16 | 2002-05-16 | Merck Patent Gmbh | Inmunoconjugados ii. |
| US5763280A (en) * | 1997-01-21 | 1998-06-09 | Coulter International Corp. | Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis |
| FR2778851B1 (fr) | 1998-05-19 | 2002-07-26 | Aetsrn | Composition a base d'inhibiteurs de cysteine-proteases pour retarder la senescence, l'autodestruction et l'hemolyse des erythrocytes |
| US8431117B2 (en) | 1999-08-30 | 2013-04-30 | David S Terman | Sickled erythrocytes with anti-tumor agents induce tumor vaso-occlusion and tumoricidal effects |
| AU2001272670A1 (en) | 2000-07-24 | 2002-02-05 | Gendel Limited | Polypeptide delivery II-2 |
| PT1495328E (pt) | 2002-04-16 | 2014-09-09 | Vlaams Interuniv Inst Biotech | Um marcador para medir cirrose hepática |
| US7501286B2 (en) | 2002-08-14 | 2009-03-10 | President And Fellows Of Harvard College | Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry |
| US7276382B2 (en) * | 2003-10-02 | 2007-10-02 | Noboru Horiguchi | Blood testing method |
| GB0325483D0 (en) | 2003-10-31 | 2003-12-03 | Plasmacute As | Assay |
| US20080095749A1 (en) | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| US7378054B2 (en) | 2004-04-16 | 2008-05-27 | Savvipharm Inc | Specimen collecting, processing and analytical assembly |
| US7803523B2 (en) * | 2004-08-27 | 2010-09-28 | University Health Network | Whole blood preparation for cytometric analysis of cell signaling pathways |
| US20060166223A1 (en) | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
| WO2006123253A2 (en) | 2005-03-29 | 2006-11-23 | Inverness Medical Switzerland Gmbh | Device and method of monitoring a patient |
| US20100184049A1 (en) | 2007-04-27 | 2010-07-22 | Steve Goodison | Glycoprotein Profiling of Bladder Cancer |
| FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| US8530182B2 (en) | 2007-12-05 | 2013-09-10 | Centers For Disease Control And Prevention | Viral protein quantification process and vaccine quality control therewith |
| US20110245092A1 (en) | 2008-03-04 | 2011-10-06 | John Bilello | Diagnosing and monitoring depression disorders based on multiple serum biomarker panels |
| KR20210003301A (ko) | 2008-05-06 | 2021-01-11 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법 |
| EP2442641A4 (en) | 2009-06-16 | 2016-03-09 | Univ Columbia | METHOD FOR REDUCING SIDE EFFECTS OF THE TRANSFUSION OF AGED RED BLOOD CELLS |
| JP6162359B2 (ja) * | 2009-06-30 | 2017-07-12 | 株式会社カネカ | 血液成分の分離システム、分離材 |
| EP2464966A1 (en) | 2009-08-13 | 2012-06-20 | Basf Se | Means and methods for diagnosingthyroid disorders |
| US20130202625A1 (en) | 2010-01-21 | 2013-08-08 | The Regents Of The University Of Californa | Use of human erythrocytes for prevention and treatment of cancer dissemination and growth |
| SG183195A1 (en) | 2010-02-08 | 2012-09-27 | Piramal Imaging Sa | F18-tyrosine derivatives for imaging bone metastases |
| WO2011127056A2 (en) | 2010-04-05 | 2011-10-13 | The Uab Research Foundation | Biomarkers for assessing exposure to ionizing radiation and absorbed dose |
| SG195180A1 (en) | 2011-05-31 | 2013-12-30 | Singapore Health Serv Pte Ltd | Method for detecting disease biomarkers |
| GB201116767D0 (en) | 2011-09-28 | 2011-11-09 | St George S Hospital Medical School | Treatment for mitrochondrial neurogastrointestinal encephalomyopathy |
| CN104394884A (zh) | 2012-03-21 | 2015-03-04 | 爱瑞泰克药物公司 | 用于治疗急性髓细胞白血病(aml)的药剂 |
| HU230341B1 (hu) | 2012-04-20 | 2016-02-29 | Advancell Diagnosztika Kft. | A vörösvérsejt-membrán kvantitatív biomarkerei |
| EP2872154B1 (en) | 2012-07-11 | 2017-05-31 | Sangamo BioSciences, Inc. | Methods and compositions for delivery of biologics |
| EP2994117B1 (en) | 2013-05-10 | 2023-06-07 | EryDel S.p.A. | Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes |
| JP6383920B2 (ja) * | 2013-09-11 | 2018-09-05 | 有限会社ピコデバイス | パーキンソン病の判定基準とする方法 |
| CN106255884B (zh) * | 2013-10-04 | 2019-01-11 | 赛尔爱迪尔私人有限公司 | 用于细胞治疗的生物标志物 |
| KR101845588B1 (ko) | 2014-04-07 | 2018-04-05 | 한양대학교 산학협력단 | 적혈구계 세포의 인 비트로 확장 |
| BR122021024421B1 (pt) | 2015-05-18 | 2022-05-03 | Hemanext Inc | Usos de um produto de sangue total armazenado reduzido de oxigênio com plaquetas |
| CA3009369A1 (en) | 2015-12-22 | 2017-06-29 | Sangui Bio Pty. Ltd | Therapeutic methods using erythrocytes |
| WO2018112500A1 (en) | 2016-12-20 | 2018-06-28 | Sangui Bio Pty. Ltd | Blood profiling with protease inhibitors |
-
2016
- 2016-10-06 CN CN201680071446.0A patent/CN108700565B/zh active Active
- 2016-10-06 EP EP21207712.7A patent/EP4009047A1/en active Pending
- 2016-10-06 AU AU2016334875A patent/AU2016334875B2/en active Active
- 2016-10-06 WO PCT/AU2016/000341 patent/WO2017059477A1/en not_active Ceased
- 2016-10-06 HK HK19100786.7A patent/HK1258470A1/zh unknown
- 2016-10-06 US US15/765,963 patent/US11243218B2/en active Active
- 2016-10-06 JP JP2018537693A patent/JP6824994B2/ja active Active
- 2016-10-06 CA CA3001154A patent/CA3001154C/en active Active
- 2016-10-06 EP EP16852887.5A patent/EP3359962B1/en active Active
- 2016-10-06 SG SG11201802754XA patent/SG11201802754XA/en unknown
- 2016-10-06 KR KR1020187012951A patent/KR102632490B1/ko active Active
- 2016-10-06 CN CN202111208795.1A patent/CN114019171A/zh active Pending
-
2021
- 2021-01-13 JP JP2021003537A patent/JP2021073453A/ja active Pending
-
2023
- 2023-03-07 JP JP2023034247A patent/JP2023078210A/ja active Pending
- 2023-11-13 US US17/845,451 patent/US20240060997A1/en active Pending
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