JP2018529625A5 - - Google Patents
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- JP2018529625A5 JP2018529625A5 JP2017551585A JP2017551585A JP2018529625A5 JP 2018529625 A5 JP2018529625 A5 JP 2018529625A5 JP 2017551585 A JP2017551585 A JP 2017551585A JP 2017551585 A JP2017551585 A JP 2017551585A JP 2018529625 A5 JP2018529625 A5 JP 2018529625A5
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- Prior art keywords
- amino acid
- acid sequence
- peptide
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- pharmaceutical composition
- Prior art date
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 16
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 206010018651 Graft versus host disease Diseases 0.000 claims 2
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007928 intraperitoneal injection Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Claims (8)
- ａ）配列番号２のアミノ酸配列からなるペプチドと、
ｂ）配列番号２のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列を含むペプチドと、
ｃ）配列番号４のアミノ酸配列からなるペプチドと、
ｄ）配列番号４のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列を含むペプチドと、
からなる群から選択される少なくとも１種のペプチドを含む、移植片対宿主病（ＧｖＨＤ）を治療又は予防するための医薬組成物。 - 前記ペプチドは、配列番号２のアミノ酸配列を含むペプチドである、請求項１に記載の医薬組成物。
- 前記ペプチドは、配列番号４のアミノ酸配列を含むペプチドである、請求項１に記載の医薬組成物。
- 前記医薬組成物の投与経路は、血管内注射、腹腔内注射、筋内注射、鼻内投与又は経口投与である、請求項１に記載の医薬組成物。
- 前記ペプチドの少なくとも２種のペプチドが併用投与されることを特徴とする、請求項１に記載の医薬組成物。
- 前記少なくとも２種のペプチドの１つは、配列番号２のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列を含むペプチドである、請求項５に記載の医薬組成物。
- 前記少なくとも２種のペプチドの１つは、配列番号４のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列を含むペプチドである、請求項５に記載の医薬組成物。
- 前記少なくとも２種のペプチドの２つは、配列番号２のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列と、配列番号４のアミノ酸配列と少なくとも８０％同一であるアミノ酸配列とを含むペプチドである、請求項５に記載の医薬組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562219900P | 2015-09-17 | 2015-09-17 | |
| US62/219,900 | 2015-09-17 | ||
| PCT/US2016/052131 WO2017049082A2 (en) | 2015-09-17 | 2016-09-16 | Compositions comprising pregnancy specific glycoproteins and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018529625A JP2018529625A (ja) | 2018-10-11 |
| JP2018529625A5 true JP2018529625A5 (ja) | 2019-10-17 |
Family
ID=58289625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551585A Pending JP2018529625A (ja) | 2015-09-17 | 2016-09-16 | 妊娠特異的糖タンパク質を含む組成物及びその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11007249B2 (ja) |
| EP (1) | EP3261722B1 (ja) |
| JP (1) | JP2018529625A (ja) |
| AU (1) | AU2016323769B2 (ja) |
| CA (1) | CA2981191C (ja) |
| WO (1) | WO2017049082A2 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3214581A1 (en) | 2021-04-14 | 2022-10-20 | Tom Moore | Treatment of cerebrovascular events and neurological disorders |
| EP4322984A1 (en) | 2021-04-14 | 2024-02-21 | University College Cork-National University of Ireland Cork | Psg1 for use in the treatment of osteoarthritis |
| WO2024078729A1 (en) | 2022-10-14 | 2024-04-18 | University College Cork - National University Of Ireland, Cork | Placenta expressed proteins for use in the treatment of tendon injury |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
| US5169835A (en) * | 1989-01-18 | 1992-12-08 | Oklahoma Medical Research Foundation | Pregancy specific proteins applications |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| CA2501940A1 (en) * | 2002-10-09 | 2004-04-22 | Tolerrx, Inc. | Molecules preferentially associated with effector t cells or regulatory t cells and methods of their use |
| AU2010286361A1 (en) * | 2009-08-31 | 2012-03-15 | Amplimmune, Inc. | Methods and compositions for the inhibition of transplant rejection |
-
2016
- 2016-09-16 JP JP2017551585A patent/JP2018529625A/ja active Pending
- 2016-09-16 AU AU2016323769A patent/AU2016323769B2/en active Active
- 2016-09-16 WO PCT/US2016/052131 patent/WO2017049082A2/en active Application Filing
- 2016-09-16 EP EP16847381.7A patent/EP3261722B1/en active Active
- 2016-09-16 US US15/561,622 patent/US11007249B2/en active Active
- 2016-09-16 CA CA2981191A patent/CA2981191C/en active Active
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