JP2018528409A5 - - Google Patents
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- Publication number
- JP2018528409A5 JP2018528409A5 JP2018502824A JP2018502824A JP2018528409A5 JP 2018528409 A5 JP2018528409 A5 JP 2018528409A5 JP 2018502824 A JP2018502824 A JP 2018502824A JP 2018502824 A JP2018502824 A JP 2018502824A JP 2018528409 A5 JP2018528409 A5 JP 2018528409A5
- Authority
- JP
- Japan
- Prior art keywords
- ina
- fluid
- freeze
- ice
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims 48
- 108010063679 ice nucleation protein Proteins 0.000 claims 27
- 238000000034 method Methods 0.000 claims 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 14
- 239000012634 fragment Substances 0.000 claims 12
- 230000006910 ice nucleation Effects 0.000 claims 12
- 239000007788 liquid Substances 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 9
- 241000588696 Pantoea ananatis Species 0.000 claims 8
- 241000588912 Pantoea agglomerans Species 0.000 claims 7
- 241000588698 Erwinia Species 0.000 claims 6
- 239000011324 bead Substances 0.000 claims 6
- 238000007710 freezing Methods 0.000 claims 5
- 230000008014 freezing Effects 0.000 claims 5
- VDHIEQOYPSVNIM-UHFFFAOYSA-N 2-hexyldecyl 2-ethylhexanoate Chemical compound CCCCCCCCC(CCCCCC)COC(=O)C(CC)CCCC VDHIEQOYPSVNIM-UHFFFAOYSA-N 0.000 claims 4
- 101100508063 Enterobacter agglomerans iceE gene Proteins 0.000 claims 4
- 101100508064 Pantoea ananas inaU gene Proteins 0.000 claims 4
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 4
- 241000589540 Pseudomonas fluorescens Species 0.000 claims 4
- 101100508065 Pseudomonas fluorescens inaW gene Proteins 0.000 claims 4
- 241000589615 Pseudomonas syringae Species 0.000 claims 4
- 101100508062 Pseudomonas syringae inaK gene Proteins 0.000 claims 4
- 101100508068 Pseudomonas syringae inaV gene Proteins 0.000 claims 4
- 101100508066 Pseudomonas syringae pv. syringae inaZ gene Proteins 0.000 claims 4
- 101100508067 Xanthomonas campestris pv. translucens inaX gene Proteins 0.000 claims 4
- 150000001720 carbohydrates Chemical class 0.000 claims 4
- 235000014633 carbohydrates Nutrition 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 101150065856 inaA gene Proteins 0.000 claims 4
- 150000002632 lipids Chemical class 0.000 claims 4
- 239000002667 nucleating agent Substances 0.000 claims 4
- 241001641548 Pseudomonas antarctica Species 0.000 claims 3
- 241001660019 Pseudomonas borealis Species 0.000 claims 3
- 241001464820 Pseudomonas viridiflava Species 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 238000001816 cooling Methods 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 239000002699 waste material Substances 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 150000002484 inorganic compounds Chemical class 0.000 claims 1
- 229910010272 inorganic material Inorganic materials 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 238000010257 thawing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195652P | 2015-07-22 | 2015-07-22 | |
| US62/195,652 | 2015-07-22 | ||
| PCT/US2016/043463 WO2017015529A1 (en) | 2015-07-22 | 2016-07-22 | Fluidic devices with freeze-thaw valves with ice-nucleating agents and related methods of operation and analysis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528409A JP2018528409A (ja) | 2018-09-27 |
| JP2018528409A5 true JP2018528409A5 (https=) | 2019-08-29 |
| JP6869949B2 JP6869949B2 (ja) | 2021-05-12 |
Family
ID=56616046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502824A Active JP6869949B2 (ja) | 2015-07-22 | 2016-07-22 | 氷核形成剤を含む凍結融解バルブを備える流体装置と関連の操作及び分析方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10864520B2 (https=) |
| EP (1) | EP3314183B1 (https=) |
| JP (1) | JP6869949B2 (https=) |
| CN (1) | CN108027203B (https=) |
| WO (1) | WO2017015529A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6200948B2 (ja) | 2012-05-25 | 2017-09-20 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | マイクロ流体デバイス |
| WO2017015529A1 (en) * | 2015-07-22 | 2017-01-26 | The University Of North Carolina At Chapel Hill | Fluidic devices with freeze-thaw valves with ice-nucleating agents and related methods of operation and analysis |
| US11016084B2 (en) | 2015-10-05 | 2021-05-25 | The University Of North Carolina At Chapel Hill | Decoding methods for multiplexing assays and associated fluidic devices, kits, and solid supports |
| WO2020068174A2 (en) | 2018-05-18 | 2020-04-02 | The University Of North Carolina At Chapel Hill | Compositions, devices, and methods for improving a surface property of a substrate |
| CN112189139B (zh) | 2018-09-26 | 2024-10-29 | 北卡罗来纳-查佩尔山大学 | 用于改进测定的化合物、组合物和方法 |
| WO2020162996A2 (en) | 2018-11-13 | 2020-08-13 | The University Of North Carolina At Chapel Hill | Analysis systems with microfluidic devices, microfluidic devices and related methods |
| KR101974979B1 (ko) * | 2019-01-14 | 2019-05-07 | 부경대학교 산학협력단 | 얼음결합단백질 자동 정제 장치 |
| CN112409553B (zh) * | 2020-11-25 | 2023-03-14 | 杭州贤石生物科技有限公司 | 微流控冰晶法制备可注射多孔水凝胶微球的方法及其应用 |
| CN112625910A (zh) * | 2020-12-23 | 2021-04-09 | 上海交通大学医学院附属新华医院 | 一种可自动置核的低温保护剂 |
| CN114440596B (zh) * | 2022-01-27 | 2022-11-29 | 华南农业大学 | 一种适用于广陈皮的干燥方法及设备 |
| US20250297975A1 (en) * | 2024-03-21 | 2025-09-25 | Funai Electric Co., Ltd. | Method and apparatus for determining water content of hygroscopic fluids |
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| US4203472A (en) | 1978-06-20 | 1980-05-20 | Dulaney Burrell C | Device for stopping fluid flow from a pipe |
| US4200228A (en) | 1978-09-18 | 1980-04-29 | Woerpel Marvin D | Snow making |
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| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4706463A (en) | 1986-09-23 | 1987-11-17 | Eastman Kodak Company | Recovery of microorganism having ice nucleating activity |
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| US5554368A (en) | 1993-12-03 | 1996-09-10 | Ecoscience Corporation | Pseudomonas syringae ATCC 55389 and use thereof for inhibiting microbial decay on fruit |
| FR2730545B1 (fr) | 1995-02-13 | 1997-03-28 | Bio Merieux | Vanne statique a congelation, et enceinte de traitement controlee par au moins une vanne |
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| FR2793008B1 (fr) | 1999-04-30 | 2001-07-27 | Valeurs Bois Ind | Procede d'extraction de jus naturel de matieres vegetales ligneuses, dispositif permettant la mise en oeuvre du procede et utilisation du procede pour la production de vegetaux ligneux seches |
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| WO2007092713A2 (en) * | 2006-02-02 | 2007-08-16 | Trustees Of The University Of Pennsylvania | Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease |
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| MX2009001504A (es) | 2006-08-10 | 2009-08-31 | California Inst Of Techn | Valvula microfluidica con un miembro de libre flotacion y su metodo de fabricacion. |
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| GB2491813A (en) | 2011-06-03 | 2012-12-19 | Univ Dublin City | A microfluidic device with sacrificial valve |
| JP6200948B2 (ja) * | 2012-05-25 | 2017-09-20 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | マイクロ流体デバイス |
| WO2017015529A1 (en) * | 2015-07-22 | 2017-01-26 | The University Of North Carolina At Chapel Hill | Fluidic devices with freeze-thaw valves with ice-nucleating agents and related methods of operation and analysis |
-
2016
- 2016-07-22 WO PCT/US2016/043463 patent/WO2017015529A1/en not_active Ceased
- 2016-07-22 EP EP16748410.4A patent/EP3314183B1/en active Active
- 2016-07-22 CN CN201680055274.8A patent/CN108027203B/zh active Active
- 2016-07-22 US US15/742,662 patent/US10864520B2/en active Active
- 2016-07-22 JP JP2018502824A patent/JP6869949B2/ja active Active
-
2020
- 2020-11-06 US US17/091,620 patent/US20210060564A1/en not_active Abandoned
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