JP2018528181A5 - - Google Patents
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- Publication number
- JP2018528181A5 JP2018528181A5 JP2018505606A JP2018505606A JP2018528181A5 JP 2018528181 A5 JP2018528181 A5 JP 2018528181A5 JP 2018505606 A JP2018505606 A JP 2018505606A JP 2018505606 A JP2018505606 A JP 2018505606A JP 2018528181 A5 JP2018528181 A5 JP 2018528181A5
- Authority
- JP
- Japan
- Prior art keywords
- carboxamide
- oxazol
- benzo
- piperidin
- pyrazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021201355A JP7339997B2 (ja) | 2015-08-04 | 2021-12-13 | ベンズアゾール化合物ならびに該化合物の作製方法および使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562200778P | 2015-08-04 | 2015-08-04 | |
| US62/200,778 | 2015-08-04 | ||
| PCT/US2016/045176 WO2017023941A1 (en) | 2015-08-04 | 2016-08-02 | Benzazole compounds and methods for making and using the compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021201355A Division JP7339997B2 (ja) | 2015-08-04 | 2021-12-13 | ベンズアゾール化合物ならびに該化合物の作製方法および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528181A JP2018528181A (ja) | 2018-09-27 |
| JP2018528181A5 true JP2018528181A5 (enExample) | 2021-08-19 |
| JP6994454B2 JP6994454B2 (ja) | 2022-01-14 |
Family
ID=56610048
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505606A Expired - Fee Related JP6994454B2 (ja) | 2015-08-04 | 2016-08-02 | ベンズアゾール化合物ならびに該化合物の作製方法および使用方法 |
| JP2021201355A Active JP7339997B2 (ja) | 2015-08-04 | 2021-12-13 | ベンズアゾール化合物ならびに該化合物の作製方法および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021201355A Active JP7339997B2 (ja) | 2015-08-04 | 2021-12-13 | ベンズアゾール化合物ならびに該化合物の作製方法および使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US10065946B2 (enExample) |
| EP (2) | EP3719016A1 (enExample) |
| JP (2) | JP6994454B2 (enExample) |
| CA (1) | CA2993661A1 (enExample) |
| DK (1) | DK3331879T3 (enExample) |
| ES (1) | ES2811136T3 (enExample) |
| HK (1) | HK1256242A1 (enExample) |
| WO (1) | WO2017023941A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1231480A1 (zh) | 2014-01-10 | 2017-12-22 | Aurigene Discovery Technologies Limited | 作为irak4抑制剂的吲唑化合物 |
| IL311677B2 (en) | 2014-01-13 | 2025-06-01 | Aurigene Oncology Ltd | Bicyclic heterocyclyl derivatives as irak4 inhibitors |
| DK3286181T3 (da) * | 2015-04-22 | 2021-04-06 | Rigel Pharmaceuticals Inc | Pyrazolforbindelser og fremgangsmåde til fremstilling og anvendelse af forbindelserne |
| HK1256242A1 (zh) | 2015-08-04 | 2019-09-20 | Rigel Pharmaceuticals, Inc. | 吲哚化合物以及制备和使用该化合物的方法 |
| TW202340194A (zh) | 2017-02-16 | 2023-10-16 | 美商基利科學股份有限公司 | 吡咯并[1,2-b]嗒𠯤衍生物 |
| CN120267671A (zh) * | 2017-03-31 | 2025-07-08 | 奥锐金肿瘤有限公司 | 用于治疗血液病的化合物和组合物 |
| JP7167069B2 (ja) * | 2017-06-29 | 2022-11-08 | ライジェル ファーマシューティカルズ， インコーポレイテッド | キナーゼ阻害剤ならびに作製および使用のための方法 |
| EP4410377A3 (en) | 2017-10-31 | 2024-11-13 | Curis, Inc. | Compounds and compositions for treating hematological disorders |
| WO2019111218A1 (en) | 2017-12-08 | 2019-06-13 | Cadila Healthcare Limited | Novel heterocyclic compounds as irak4 inhibitors |
| TWI721483B (zh) | 2018-07-13 | 2021-03-11 | 美商基利科學股份有限公司 | 吡咯并[1,2-b]嗒𠯤衍生物 |
| CN112043696B (zh) * | 2020-08-26 | 2023-02-24 | 深圳市第二人民医院(深圳市转化医学研究院) | Ido-1抑制剂在制备治疗骨性关节炎药物中的应用 |
| WO2022187303A1 (en) | 2021-03-03 | 2022-09-09 | Rigel Pharmaceuticals, Inc. | A method for treating a disease or condition using a pyrazole compound or formulation thereof |
| CA3214747A1 (en) | 2021-04-08 | 2022-10-13 | Reinhard Von Roemeling | Combination therapies for the treatment of cancer |
| EP4399208A4 (en) * | 2021-09-08 | 2025-07-16 | Rigel Pharmaceuticals Inc | IRAK INHIBITOR FOR TREATING CYTOKINE RELEASE CONDITIONS ASSOCIATED WITH RESPIRATORY VIRUS INFECTION |
| CN117177965B (zh) * | 2021-12-23 | 2024-04-30 | 杭州多域生物技术有限公司 | 一种五元并六元化合物、制备方法、药物组合物和应用 |
| ES3075943T3 (en) | 2022-03-23 | 2026-08-10 | Rigel Pharmaceuticals Inc | Pyrimid-2-yl-pyrazole compounds as irak inhibitors |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5087240A (en) | 1983-08-18 | 1992-02-11 | Drug Delivery Systems Inc. | Transdermal drug patch with conductive fibers |
| US4921475A (en) | 1983-08-18 | 1990-05-01 | Drug Delivery Systems Inc. | Transdermal drug patch with microtubes |
| US4738851A (en) | 1985-09-27 | 1988-04-19 | University Of Iowa Research Foundation, Inc. | Controlled release ophthalmic gel formulation |
| US5163899A (en) | 1987-03-20 | 1992-11-17 | Drug Delivery Systems Inc. | Transdermal drug delivery system |
| US5312325A (en) | 1987-05-28 | 1994-05-17 | Drug Delivery Systems Inc | Pulsating transdermal drug delivery system |
| GB8804164D0 (en) | 1988-02-23 | 1988-03-23 | Tucker J M | Bandage for administering physiologically active compound |
| US4882150A (en) | 1988-06-03 | 1989-11-21 | Kaufman Herbert E | Drug delivery system |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5088977A (en) | 1988-12-21 | 1992-02-18 | Drug Delivery Systems Inc. | Electrical transdermal drug applicator with counteractor and method of drug delivery |
| US5521222A (en) | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| CA2031376A1 (en) | 1989-12-04 | 1991-06-05 | Bahram Farhadieh | Single layer transdermal drug administration system |
| US5077033A (en) | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
| DK0495421T3 (da) | 1991-01-15 | 1996-12-09 | Alcon Lab Inc | Anvendelse af carragenaner i topiske ophthalmiske sammensætninger |
| US5352456A (en) | 1991-10-10 | 1994-10-04 | Cygnus Therapeutic Systems | Device for administering drug transdermally which provides an initial pulse of drug |
| CA2123809A1 (en) | 1991-12-18 | 1993-06-24 | Debra L. Wilfong | Multilayered barrier structures |
| ATE132381T1 (de) | 1992-01-29 | 1996-01-15 | Voelkl Franz Ski | Ballspielschläger, insbesondere tennisschläger |
| IL114193A (en) | 1994-06-20 | 2000-02-29 | Teva Pharma | Ophthalmic pharmaceutical compositions based on sodium alginate |
| ES2094688B1 (es) | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| IT1283911B1 (it) | 1996-02-05 | 1998-05-07 | Farmigea Spa | Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo |
| US5800807A (en) | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
| US6261547B1 (en) | 1998-04-07 | 2001-07-17 | Alcon Manufacturing, Ltd. | Gelling ophthalmic compositions containing xanthan gum |
| US6197934B1 (en) | 1998-05-22 | 2001-03-06 | Collagenesis, Inc. | Compound delivery using rapidly dissolving collagen film |
| JP2012254939A (ja) | 2009-10-07 | 2012-12-27 | Astellas Pharma Inc | オキサゾール化合物 |
| WO2013042137A1 (en) * | 2011-09-19 | 2013-03-28 | Aurigene Discovery Technologies Limited | Bicyclic heterocycles as irak4 inhibitors |
| TW201728592A (zh) | 2012-01-10 | 2017-08-16 | 林伯士艾瑞斯公司 | Ｉｒａｋ抑制劑及其用途 |
| EP3049086A4 (en) * | 2013-09-27 | 2017-02-22 | Nimbus Iris, Inc. | Irak inhibitors and uses thereof |
| TWI667233B (zh) * | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺，其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
| WO2015104668A2 (en) * | 2014-01-09 | 2015-07-16 | Camus Pharma Pvt. Ltd. | Lyophilized formulations for parenteral use |
| HK1231480A1 (zh) * | 2014-01-10 | 2017-12-22 | Aurigene Discovery Technologies Limited | 作为irak4抑制剂的吲唑化合物 |
| IL311677B2 (en) * | 2014-01-13 | 2025-06-01 | Aurigene Oncology Ltd | Bicyclic heterocyclyl derivatives as irak4 inhibitors |
| HK1256242A1 (zh) * | 2015-08-04 | 2019-09-20 | Rigel Pharmaceuticals, Inc. | 吲哚化合物以及制备和使用该化合物的方法 |
-
2016
- 2016-08-02 HK HK18115278.1A patent/HK1256242A1/zh unknown
- 2016-08-02 EP EP20175472.8A patent/EP3719016A1/en not_active Withdrawn
- 2016-08-02 JP JP2018505606A patent/JP6994454B2/ja not_active Expired - Fee Related
- 2016-08-02 US US15/226,625 patent/US10065946B2/en active Active
- 2016-08-02 DK DK16748048.2T patent/DK3331879T3/da active
- 2016-08-02 CA CA2993661A patent/CA2993661A1/en active Pending
- 2016-08-02 WO PCT/US2016/045176 patent/WO2017023941A1/en not_active Ceased
- 2016-08-02 ES ES16748048T patent/ES2811136T3/es active Active
- 2016-08-02 EP EP16748048.2A patent/EP3331879B1/en active Active
-
2018
- 2018-08-07 US US16/057,687 patent/US10774076B2/en active Active
-
2020
- 2020-07-14 US US16/928,413 patent/US11299486B2/en active Active
-
2021
- 2021-12-13 JP JP2021201355A patent/JP7339997B2/ja active Active
-
2022
- 2022-03-07 US US17/687,826 patent/US12043620B2/en active Active
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