JP2018524351A5 - - Google Patents
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- Publication number
- JP2018524351A5 JP2018524351A5 JP2017568354A JP2017568354A JP2018524351A5 JP 2018524351 A5 JP2018524351 A5 JP 2018524351A5 JP 2017568354 A JP2017568354 A JP 2017568354A JP 2017568354 A JP2017568354 A JP 2017568354A JP 2018524351 A5 JP2018524351 A5 JP 2018524351A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- preparation
- ammonia oxidizing
- oxidizing bacteria
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 description 97
- 238000002360 preparation method Methods 0.000 description 60
- 241001453382 Nitrosomonadales Species 0.000 description 36
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 24
- 239000000654 additive Substances 0.000 description 24
- 206010000496 acne Diseases 0.000 description 22
- 230000000996 additive effect Effects 0.000 description 22
- 208000002874 Acne Vulgaris Diseases 0.000 description 20
- 238000011282 treatment Methods 0.000 description 20
- 241000894006 Bacteria Species 0.000 description 16
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 12
- 229910021529 ammonia Inorganic materials 0.000 description 12
- 230000001590 oxidative effect Effects 0.000 description 10
- 241000186427 Cutibacterium acnes Species 0.000 description 9
- 229940055019 propionibacterium acne Drugs 0.000 description 9
- 239000012062 aqueous buffer Substances 0.000 description 8
- 239000007853 buffer solution Substances 0.000 description 8
- 230000003902 lesion Effects 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- -1 stick Substances 0.000 description 8
- 239000003595 mist Substances 0.000 description 7
- 239000000443 aerosol Substances 0.000 description 6
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 6
- 229910000397 disodium phosphate Inorganic materials 0.000 description 6
- 235000019800 disodium phosphate Nutrition 0.000 description 6
- 229910001629 magnesium chloride Inorganic materials 0.000 description 6
- 208000017520 skin disease Diseases 0.000 description 6
- 239000001488 sodium phosphate Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 244000052616 bacterial pathogen Species 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 5
- 239000003599 detergent Substances 0.000 description 5
- 239000002453 shampoo Substances 0.000 description 5
- 241000605120 Nitrosomonas eutropha Species 0.000 description 4
- 239000003086 colorant Substances 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 239000003205 fragrance Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000002674 ointment Substances 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000000977 initiatory effect Effects 0.000 description 3
- 238000011200 topical administration Methods 0.000 description 3
- 108020000946 Bacterial DNA Proteins 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 241000186660 Lactobacillus Species 0.000 description 2
- 241000192147 Nitrosococcus Species 0.000 description 2
- 241000605122 Nitrosomonas Species 0.000 description 2
- 241001495394 Nitrosospira Species 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 2
- 150000003863 ammonium salts Chemical class 0.000 description 2
- 230000000181 anti-adherent effect Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 239000002981 blocking agent Substances 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000013270 controlled release Methods 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 239000002781 deodorant agent Substances 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 235000003599 food sweetener Nutrition 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 239000000077 insect repellent Substances 0.000 description 2
- 229940039696 lactobacillus Drugs 0.000 description 2
- 239000000314 lubricant Substances 0.000 description 2
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 230000036555 skin type Effects 0.000 description 2
- 239000000344 soap Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000003765 sweetening agent Substances 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 239000004342 Benzoyl peroxide Substances 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 206010036229 Post inflammatory pigmentation change Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 208000009736 adult acne Diseases 0.000 description 1
- 230000002280 anti-androgenic effect Effects 0.000 description 1
- 239000000051 antiandrogen Substances 0.000 description 1
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 229960005280 isotretinoin Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562188343P | 2015-07-02 | 2015-07-02 | |
| US62/188,343 | 2015-07-02 | ||
| US201562189105P | 2015-07-06 | 2015-07-06 | |
| US62/189,105 | 2015-07-06 | ||
| US14/882,284 US9738870B2 (en) | 2014-04-15 | 2015-10-13 | Ammonia oxidizing bacteria for treatment of acne |
| US14/882,284 | 2015-10-13 | ||
| PCT/US2016/040756 WO2017004557A1 (en) | 2015-07-02 | 2016-07-01 | Ammonia oxidizing bacteria for treatment of acne |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020216521A Division JP2021050238A (ja) | 2015-07-02 | 2020-12-25 | ざ瘡の処置のためのアンモニア酸化細菌 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524351A JP2018524351A (ja) | 2018-08-30 |
| JP2018524351A5 true JP2018524351A5 (enExample) | 2019-08-08 |
| JP7606726B2 JP7606726B2 (ja) | 2024-12-26 |
Family
ID=88967788
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568354A Active JP7606726B2 (ja) | 2015-07-02 | 2016-07-01 | ざ瘡の処置のためのアンモニア酸化細菌 |
| JP2020216521A Withdrawn JP2021050238A (ja) | 2015-07-02 | 2020-12-25 | ざ瘡の処置のためのアンモニア酸化細菌 |
| JP2023146929A Pending JP2023162452A (ja) | 2015-07-02 | 2023-09-11 | ざ瘡の処置のためのアンモニア酸化細菌 |
| JP2025031515A Pending JP2025084894A (ja) | 2015-07-02 | 2025-02-28 | ざ瘡の処置のためのアンモニア酸化細菌 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020216521A Withdrawn JP2021050238A (ja) | 2015-07-02 | 2020-12-25 | ざ瘡の処置のためのアンモニア酸化細菌 |
| JP2023146929A Pending JP2023162452A (ja) | 2015-07-02 | 2023-09-11 | ざ瘡の処置のためのアンモニア酸化細菌 |
| JP2025031515A Pending JP2025084894A (ja) | 2015-07-02 | 2025-02-28 | ざ瘡の処置のためのアンモニア酸化細菌 |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP3316900B1 (enExample) |
| JP (4) | JP7606726B2 (enExample) |
| KR (2) | KR20250026389A (enExample) |
| CN (1) | CN108367029A (enExample) |
| AU (2) | AU2016288256B2 (enExample) |
| BR (1) | BR112018000056A2 (enExample) |
| CA (1) | CA2991170A1 (enExample) |
| IL (2) | IL256617B (enExample) |
| MX (2) | MX386941B (enExample) |
| PH (1) | PH12018500015A1 (enExample) |
| RU (1) | RU2753125C2 (enExample) |
| SG (1) | SG10201913983TA (enExample) |
| WO (1) | WO2017004557A1 (enExample) |
| ZA (2) | ZA201800030B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3037703A1 (en) * | 2016-09-21 | 2018-03-29 | Aobiome Llc | Ammonia oxidizing microorganisms for use and delivery to the intranasal system |
| TW201907934A (zh) * | 2017-07-18 | 2019-03-01 | 美商微辰生命有限公司 | 用於治療肺動脈高血壓之氨氧化微生物 |
| US20200179461A1 (en) * | 2017-07-18 | 2020-06-11 | Aobiome Llc | Ammonia oxidizing microorganisms for the treatment of headaches |
| WO2019018425A1 (en) * | 2017-07-18 | 2019-01-24 | Aobiome Llc | AMMONIA-OXIDIZING MICROORGANISMS FOR INJECTION USE AND ADMINISTRATION |
| WO2019126711A1 (en) * | 2017-12-22 | 2019-06-27 | Aobiome Llc | Veterinary use and delivery of ammonia oxidizing microorganisms |
| JP7520366B2 (ja) | 2018-04-16 | 2024-07-23 | オンクオリティー ファーマシューティカルズ チャイナ リミテッド | 腫瘍療法の副作用の予防または治療方法 |
| WO2021237154A2 (en) * | 2020-05-21 | 2021-11-25 | Aobiome Llc | Shelf- stable ammonia oxidizing microorganism preparations |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1243390B (it) | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| US5314542A (en) | 1993-08-06 | 1994-05-24 | Precision Aquarium Testing, Inc. | Nitrosomonas preservation and reactivation for aquaria |
| FR2774674B1 (fr) | 1998-02-10 | 2000-03-24 | Atochem Elf Sa | Procede de preparation d'une solution aqueuse de peroxyde d'hydrogene directement a partir d'hydrogene et d'oxygene et dispositif permettant sa mise en oeuvre |
| CN1267212C (zh) * | 2000-08-11 | 2006-08-02 | 大卫·R·怀特洛克 | 氨氧化细菌在药物中的应用、由其制成的制剂及用其处理过的用品 |
| US20050244382A9 (en) * | 2002-01-11 | 2005-11-03 | Whitlock David R | Compositions including ammonia oxidizing bacteria and methods of using same |
| ZA200602720B (en) * | 2003-09-26 | 2007-09-26 | David R Whitlock | Methods of using ammonia oxidizing bacteria |
| JP2007508247A (ja) * | 2003-09-26 | 2007-04-05 | ホイットロック，デービッド，アール． | アンモニア酸化細菌の使用方法 |
| FR2938437B1 (fr) * | 2008-11-19 | 2020-03-27 | Société des Produits Nestlé S.A. | Utilisation cosmetique de microorganisme pour le traitement des peaux grasses |
| ES2958410T3 (es) | 2009-08-21 | 2024-02-08 | Novan Inc | Geles tópicos |
| US8591876B2 (en) * | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
| JP7088986B2 (ja) | 2014-04-15 | 2022-06-21 | エーオーバイオーム， エルエルシー． | アンモニア酸化Ｎｉｔｒｏｓｏｍｏｎａｓ ｅｕｔｒｏｐｈａ株Ｄ２３ |
| WO2015160911A2 (en) | 2014-04-15 | 2015-10-22 | Aobiome Llc | Ammonia-oxidizing nitrosomonas eutropha strain d23 |
| WO2015179669A1 (en) * | 2014-05-22 | 2015-11-26 | Aobiome Llc | Methods of preparing materials with ammonia oxidizing bacteria and testing materials for ammonia oxidizing bacteria |
| RU2613708C2 (ru) * | 2014-11-07 | 2017-03-21 | Бюджетное учреждение высшего образования Ханты-Мансийского автономного округа - Югра "Ханты-Мансийская государственная медицинская академия" | Способ лечения угревой болезни |
| AU2016287746A1 (en) | 2015-07-02 | 2018-01-25 | Aobiome Llc | Microbiome-compatible cosmetics |
-
2016
- 2016-07-01 MX MX2018000274A patent/MX386941B/es unknown
- 2016-07-01 RU RU2018103906A patent/RU2753125C2/ru active
- 2016-07-01 WO PCT/US2016/040756 patent/WO2017004557A1/en not_active Ceased
- 2016-07-01 AU AU2016288256A patent/AU2016288256B2/en active Active
- 2016-07-01 CA CA2991170A patent/CA2991170A1/en active Pending
- 2016-07-01 KR KR1020257004651A patent/KR20250026389A/ko active Pending
- 2016-07-01 CN CN201680049386.2A patent/CN108367029A/zh active Pending
- 2016-07-01 JP JP2017568354A patent/JP7606726B2/ja active Active
- 2016-07-01 EP EP16739645.6A patent/EP3316900B1/en active Active
- 2016-07-01 EP EP21177270.2A patent/EP3943160A1/en active Pending
- 2016-07-01 KR KR1020187002887A patent/KR102769297B1/ko active Active
- 2016-07-01 SG SG10201913983TA patent/SG10201913983TA/en unknown
- 2016-07-01 BR BR112018000056A patent/BR112018000056A2/pt not_active Application Discontinuation
-
2017
- 2017-12-27 IL IL256617A patent/IL256617B/en unknown
-
2018
- 2018-01-03 PH PH12018500015A patent/PH12018500015A1/en unknown
- 2018-01-03 ZA ZA2018/00030A patent/ZA201800030B/en unknown
- 2018-01-08 MX MX2021011152A patent/MX2021011152A/es unknown
-
2020
- 2020-12-25 JP JP2020216521A patent/JP2021050238A/ja not_active Withdrawn
-
2021
- 2021-09-19 IL IL286488A patent/IL286488B2/en unknown
-
2022
- 2022-10-26 ZA ZA2022/11665A patent/ZA202211665B/en unknown
- 2022-11-24 AU AU2022275473A patent/AU2022275473A1/en active Pending
-
2023
- 2023-09-11 JP JP2023146929A patent/JP2023162452A/ja active Pending
-
2025
- 2025-02-28 JP JP2025031515A patent/JP2025084894A/ja active Pending
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