|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
US3817837A
(en)
|
1971-05-14 |
1974-06-18 |
Syva Corp |
Enzyme amplification assay
|
|
US3939350A
(en)
|
1974-04-29 |
1976-02-17 |
Board Of Trustees Of The Leland Stanford Junior University |
Fluorescent immunoassay employing total reflection for activation
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4277437A
(en)
|
1978-04-05 |
1981-07-07 |
Syva Company |
Kit for carrying out chemically induced fluorescence immunoassay
|
|
US4366241A
(en)
|
1980-08-07 |
1982-12-28 |
Syva Company |
Concentrating zone method in heterogeneous immunoassays
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
FR2646438B1
(fr)
|
1989-03-20 |
2007-11-02 |
Pasteur Institut |
Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
ATE300615T1
(de)
|
1990-08-29 |
2005-08-15 |
Genpharm Int |
Transgene mäuse fähig zur produktion heterologer antikörper
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
DE69232137T2
(de)
|
1991-11-25 |
2002-05-29 |
Enzon Inc |
Multivalente antigen-bindende proteine
|
|
ES2341666T3
(es)
|
1991-12-02 |
2010-06-24 |
Medimmune Limited |
Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
|
|
WO1993022332A2
(en)
|
1992-04-24 |
1993-11-11 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
US5639641A
(en)
*
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
WO1998052976A1
(en)
|
1997-05-21 |
1998-11-26 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
US7083950B2
(en)
*
|
1998-09-25 |
2006-08-01 |
Regeneron Pharmaceuticals, Inc. |
High affinity fusion proteins and therapeutic and diagnostic methods for use
|
|
US6586251B2
(en)
|
2000-10-31 |
2003-07-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US7105348B2
(en)
|
2000-10-31 |
2006-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
CN1487996B
(zh)
|
2000-11-30 |
2010-06-16 |
米德列斯公司 |
用于生产人类抗体的转基因转染色体啮齿动物
|
|
EP1732600A2
(en)
|
2004-03-26 |
2006-12-20 |
Pfizer Products Incorporated |
Uses of anti-ctla-4 antibodies
|
|
CA2575791A1
(en)
*
|
2004-08-03 |
2006-02-16 |
Dyax Corp. |
Hk1-binding proteins
|
|
AU2008323206B2
(en)
|
2007-11-12 |
2014-08-14 |
U3 Pharma Gmbh |
AXL antibodies
|
|
DK2356270T3
(da)
|
2008-11-07 |
2016-12-12 |
Fabrus Llc |
Kombinatoriske antistofbiblioteker og anvendelser deraf
|
|
JO3672B1
(ar)
|
2008-12-15 |
2020-08-27 |
Regeneron Pharma |
أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
|
|
EP2408814B1
(en)
|
2009-03-20 |
2018-11-21 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
BRPI1013428A2
(pt)
|
2009-05-11 |
2019-07-02 |
U3 Pharma Gmbh |
anticorpos humanizados para axl
|
|
WO2011042548A1
(en)
*
|
2009-10-09 |
2011-04-14 |
Sanofi-Aventis |
Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same
|
|
BR112012027995A2
(pt)
*
|
2010-06-18 |
2017-01-10 |
Genentech Inc |
anticorpo e ácido nucleíco isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, uso do anticorpo, método de tratamento de um indivíduo com câncer, de um indivíduo possuíndo um distúrbio imune, de inibição da angiogênese e para inibir a ativação constitutiva de axl
|
|
WO2012141899A1
(en)
*
|
2011-04-14 |
2012-10-18 |
Bright View Technologies Corporation |
Light transmissive structures and fabrication methods for controlling far-field light distribution
|
|
CN103747803B
(zh)
*
|
2011-06-22 |
2016-10-12 |
国家医疗保健研究所 |
抗axl抗体及其用途
|
|
AU2012273954A1
(en)
|
2011-06-22 |
2014-01-09 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Anti-Axl antibodies and uses thereof
|
|
US20140121126A1
(en)
*
|
2012-10-25 |
2014-05-01 |
Memorial Sloan-Kettering Cancer Center |
Methods of detecting axl and gas6 in cancer patients
|
|
PL2914630T3
(pl)
*
|
2012-11-05 |
2021-09-06 |
Pierre Fabre Médicament |
Nowe białka wiążące antygen i ich zastosowanie jako produktu ukierunkowanego do leczenia raka
|
|
WO2016187356A1
(en)
*
|
2015-05-18 |
2016-11-24 |
Agensys, Inc. |
Antibodies that bind to axl proteins
|
|
WO2016187354A1
(en)
|
2015-05-18 |
2016-11-24 |
Agensys, Inc. |
Antibodies that bind to axl proteins
|
|
WO2018010140A1
(zh)
*
|
2016-07-14 |
2018-01-18 |
中国科学院生物物理研究所 |
I型干扰素受体抗体及其用途
|
|
BR112022017986A2
(pt)
*
|
2020-03-09 |
2022-12-13 |
Abcellera Biologics Inc |
Anticorpos anticoronavírus e métodos de uso
|
|
JP2024505636A
(ja)
*
|
2021-01-15 |
2024-02-07 |
ザ ロックフェラー ユニバーシティー |
抗ｓａｒｓ－ｃｏｖ－２中和抗体
|