JP2018515623A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018515623A5 JP2018515623A5 JP2018512823A JP2018512823A JP2018515623A5 JP 2018515623 A5 JP2018515623 A5 JP 2018515623A5 JP 2018512823 A JP2018512823 A JP 2018512823A JP 2018512823 A JP2018512823 A JP 2018512823A JP 2018515623 A5 JP2018515623 A5 JP 2018515623A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- nhc
- cancer
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CN(C(*)*=C(**C(N(*)C(*)(*N)I[Al])=O)C1)C=*1*=C Chemical compound CN(C(*)*=C(**C(N(*)C(*)(*N)I[Al])=O)C1)C=*1*=C 0.000 description 5
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163369P | 2015-05-18 | 2015-05-18 | |
| US62/163,369 | 2015-05-18 | ||
| US201562203070P | 2015-08-10 | 2015-08-10 | |
| US62/203,070 | 2015-08-10 | ||
| PCT/US2016/033111 WO2016187324A1 (en) | 2015-05-18 | 2016-05-18 | Heterocyclic compounds as kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018515623A JP2018515623A (ja) | 2018-06-14 |
| JP2018515623A5 true JP2018515623A5 (OSRAM) | 2019-06-27 |
Family
ID=57320732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018512823A Withdrawn JP2018515623A (ja) | 2015-05-18 | 2016-05-18 | キナーゼ阻害剤としての複素環式化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10392402B2 (OSRAM) |
| EP (1) | EP3297437A4 (OSRAM) |
| JP (1) | JP2018515623A (OSRAM) |
| CN (1) | CN107835637A (OSRAM) |
| AU (1) | AU2016264220A1 (OSRAM) |
| CA (1) | CA3024113A1 (OSRAM) |
| HK (1) | HK1248070A1 (OSRAM) |
| IL (1) | IL255750A (OSRAM) |
| WO (1) | WO2016187324A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210069016A1 (en) * | 2008-11-13 | 2021-03-11 | Gholam A. Peyman | Neurodegenerative Disorder Treatment Method |
| CA2939021C (en) | 2014-02-11 | 2022-07-12 | Bayer Pharma Aktiengesellschaft | Benzimidazol-2-amines as midh1 inhibitors |
| WO2015121210A1 (en) | 2014-02-11 | 2015-08-20 | Bayer Pharma Aktiengesellschaft | Benzimidazol-2-amines as midh1 inhibitors |
| JP2018515623A (ja) * | 2015-05-18 | 2018-06-14 | トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー | キナーゼ阻害剤としての複素環式化合物 |
| AU2020273376C1 (en) * | 2016-10-24 | 2024-02-29 | Translational Drug Development, Llc | Amide compounds as kinase inhibitors, compositions and methods of treatment |
| CN110382481A (zh) * | 2016-11-21 | 2019-10-25 | 转化药物开发有限责任公司 | 作为激酶抑制剂的杂环化合物 |
| WO2020142745A1 (en) * | 2019-01-04 | 2020-07-09 | Translational Drug Development, Llc | Methods of treating graft versus host disease and neoplastic disease with amide compounds |
| CA3097638A1 (en) * | 2018-04-24 | 2019-10-31 | Translational Drug Development, Llc | Amide compounds as kinase inhibitors, compositions and methods of treatment |
| EP4059928A4 (en) * | 2019-11-15 | 2023-11-15 | Wuhan LL Science and Technology Development Co., Ltd. | Rock inhibitor, preparation method therefor and use thereof |
| EP3845276B1 (en) | 2019-12-31 | 2025-01-29 | Industrial Technology Research Institute | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same |
| CR20220375A (es) * | 2020-01-07 | 2022-09-22 | Disarm Therapeutics Inc | Inhibidores de sarm1 |
| US12404265B2 (en) | 2020-08-04 | 2025-09-02 | Nura Bio, Inc. | Substituted pyridine derivatives as SARM1 inhibitors |
| CN116438171A (zh) | 2020-09-16 | 2023-07-14 | 努拉生物公司 | 作为sarm1抑制剂的取代的吡啶衍生物 |
| JP2024528036A (ja) | 2021-07-28 | 2024-07-26 | ヌラ バイオ，インク． | Ｓａｒｍ１阻害剤としての置換ピリジン誘導体 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2620818A1 (en) | 2005-09-02 | 2007-03-08 | Astellas Pharma Inc. | Amide derivatives as rock inhibitors |
| EP2234486A4 (en) * | 2007-12-19 | 2011-09-14 | Scripps Research Inst | BENZIMIDAZOLES AND ANALOGS AS INHIBITORS OF RHO-KINASE |
| US20090258907A1 (en) | 2008-04-09 | 2009-10-15 | Abbott Laboratories | Compounds useful as inhibitors of rock kinases |
| US20130129677A1 (en) | 2009-02-27 | 2013-05-23 | Siga Technologies, Inc. | Thienopyridine Derivatives for the Treatment and Prevention of Dengue Virus Infections |
| AR078793A1 (es) * | 2009-10-27 | 2011-12-07 | Orion Corp | Derivados de carboxamidas no esteroidales y acil hidrazona moduladores de receptores androgenicos de tejido selectivo (sarm), composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del cancer de prostata entre otros |
| US9221808B2 (en) * | 2010-04-16 | 2015-12-29 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinase (ROCK) and methods of use |
| US8697911B2 (en) * | 2010-07-07 | 2014-04-15 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| US9284298B2 (en) * | 2011-04-11 | 2016-03-15 | Nerviano Medical Sciences S.R.L. | Pyrazolyl-pyrimidine derivatives as kinase inhibitors |
| JP2018515623A (ja) * | 2015-05-18 | 2018-06-14 | トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー | キナーゼ阻害剤としての複素環式化合物 |
-
2016
- 2016-05-18 JP JP2018512823A patent/JP2018515623A/ja not_active Withdrawn
- 2016-05-18 WO PCT/US2016/033111 patent/WO2016187324A1/en not_active Ceased
- 2016-05-18 AU AU2016264220A patent/AU2016264220A1/en not_active Abandoned
- 2016-05-18 HK HK18107657.9A patent/HK1248070A1/zh unknown
- 2016-05-18 US US15/574,800 patent/US10392402B2/en active Active
- 2016-05-18 EP EP16797227.2A patent/EP3297437A4/en not_active Withdrawn
- 2016-05-18 CA CA3024113A patent/CA3024113A1/en not_active Abandoned
- 2016-05-18 CN CN201680041168.4A patent/CN107835637A/zh active Pending
-
2017
- 2017-11-19 IL IL255750A patent/IL255750A/en unknown
-
2019
- 2019-08-26 US US16/551,694 patent/US10633393B2/en active Active
-
2020
- 2020-04-27 US US16/859,977 patent/US20200255448A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018515623A5 (OSRAM) | ||
| KR101937501B1 (ko) | 치환된 2,3-디히드로이미다조[1,2-ｃ]퀴나졸린 염 | |
| CN103717604B (zh) | 取代的氨基咪唑并哒嗪 | |
| CN103687858B (zh) | 作为mknk1激酶抑制剂的氨基取代的咪唑并哒嗪 | |
| JP2021507900A5 (OSRAM) | ||
| JP2021508686A5 (OSRAM) | ||
| JP6173426B2 (ja) | アミノ置換イミダゾピリダジン | |
| JP6147761B2 (ja) | アミノ置換イミダゾピリダジン | |
| RU2017122824A (ru) | Пирролопиримидиновое соединение | |
| JP6174583B2 (ja) | アミノ置換イミダゾピリダジン | |
| ES2646916T3 (es) | Aminoimidazopiridazinas como inhibidores de MKNK1 cinasa | |
| CN110582489A (zh) | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 | |
| CN110573501A (zh) | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 | |
| PH12018500765B1 (en) | N-sulfonylated pyrazolo[3,4-b]pyridin-6-carboxamides and method of use | |
| JP2017532360A5 (OSRAM) | ||
| JP2019518766A5 (OSRAM) | ||
| JP2017520607A5 (OSRAM) | ||
| JP2020517616A5 (OSRAM) | ||
| MX2018004364A (es) | Acidos pirazolo [3,4-b] piridin-6-carboxilicos sustituidos y su uso. | |
| TW201544107A (zh) | Ｈｓｐ９０抑制劑之組合 | |
| JP2018529745A5 (OSRAM) | ||
| JP2020502066A5 (OSRAM) | ||
| JP2019535812A5 (OSRAM) | ||
| JP2018509441A5 (OSRAM) | ||
| CA2993809C (en) | Compounds and pharmaceutical composition associated with ubiquitination-proteasome system |