JP2018511648A5 - - Google Patents
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- Publication number
- JP2018511648A5 JP2018511648A5 JP2017555866A JP2017555866A JP2018511648A5 JP 2018511648 A5 JP2018511648 A5 JP 2018511648A5 JP 2017555866 A JP2017555866 A JP 2017555866A JP 2017555866 A JP2017555866 A JP 2017555866A JP 2018511648 A5 JP2018511648 A5 JP 2018511648A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- alkyl
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims description 31
- 150000003839 salts Chemical class 0.000 claims description 18
- 102100021977 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Human genes 0.000 claims description 10
- 108050004000 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Proteins 0.000 claims description 10
- 238000012879 PET imaging Methods 0.000 claims description 8
- 238000003384 imaging method Methods 0.000 claims description 6
- 238000001727 in vivo Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 238000002603 single-photon emission computed tomography Methods 0.000 claims description 6
- 229910052736 halogen Inorganic materials 0.000 claims description 4
- 125000005843 halogen group Chemical group 0.000 claims description 4
- 239000003446 ligand Substances 0.000 claims description 4
- 125000004429 atom Chemical group 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 238000011260 co-administration Methods 0.000 claims description 2
- 125000002971 oxazolyl group Chemical group 0.000 claims description 2
- 125000004076 pyridyl group Chemical group 0.000 claims description 2
- 125000001424 substituent group Chemical group 0.000 claims description 2
- 239000000758 substrate Substances 0.000 claims description 2
- 230000002285 radioactive effect Effects 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562105336P | 2015-01-20 | 2015-01-20 | |
| US62/105,336 | 2015-01-20 | ||
| PCT/IB2016/050276 WO2016116875A1 (en) | 2015-01-20 | 2016-01-20 | Pet imaging agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020106739A Division JP2020158532A (ja) | 2015-01-20 | 2020-06-22 | Ｐｅｔイメージング剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511648A JP2018511648A (ja) | 2018-04-26 |
| JP2018511648A5 true JP2018511648A5 (cg-RX-API-DMAC7.html) | 2019-02-21 |
| JP6723264B2 JP6723264B2 (ja) | 2020-07-15 |
Family
ID=55300733
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555866A Expired - Fee Related JP6723264B2 (ja) | 2015-01-20 | 2016-01-20 | Ｐｅｔイメージング剤 |
| JP2020106739A Pending JP2020158532A (ja) | 2015-01-20 | 2020-06-22 | Ｐｅｔイメージング剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020106739A Pending JP2020158532A (ja) | 2015-01-20 | 2020-06-22 | Ｐｅｔイメージング剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10450298B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3247706B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6723264B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20170103960A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107406419B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016209906A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017015455A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2974311A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201791643A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2828715T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2017009452A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016116875A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016209906A1 (en) | 2015-01-20 | 2017-08-03 | Novartis Ag | PET imaging agents |
| TWI809597B (zh) * | 2020-12-16 | 2023-07-21 | 美商美國禮來大藥廠 | 預靶向造影劑 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0224917D0 (en) * | 2002-10-25 | 2002-12-04 | Novartis Ag | Organic compounds |
| WO2005043300A2 (en) | 2003-10-20 | 2005-05-12 | Empirix, Inc. | Computer language interpretation and optimization for server testing |
| US20070259863A1 (en) | 2004-04-28 | 2007-11-08 | Icos Corporation | Arylphenylamino-,Arylphenylamide-, and Arylphenylether-Sulfide Derivatives |
| WO2005121094A1 (en) | 2004-06-09 | 2005-12-22 | Pfizer Limited | Piperazine and piperidine derivatives as anti-hiv-agents |
| CN101429161A (zh) * | 2008-12-05 | 2009-05-13 | 常熟理工学院 | Pet显像剂前体异喹啉甲酰胺衍生物的合成方法 |
| JP5767205B2 (ja) * | 2009-04-02 | 2015-08-19 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | オートタキシン阻害剤としての複素環式化合物 |
| WO2012020567A1 (en) | 2010-08-09 | 2012-02-16 | Raqualia Pharma Inc. | Acyl piperazine derivatives as ttx-s blockers |
| US9000025B2 (en) * | 2010-08-20 | 2015-04-07 | Amira Pharmaceuticals, Inc. | Autotaxin inhibitors and uses thereof |
| EA201492223A1 (ru) * | 2012-06-13 | 2015-03-31 | Ф. Хоффманн-Ля Рош Аг | Новые диазаспироциклоалканы и азаспироциклоалканы |
| SG11201504633PA (en) | 2012-12-19 | 2015-07-30 | Novartis Ag | Autotaxin inhibitors |
| ES2742077T3 (es) | 2013-07-18 | 2020-02-13 | Novartis Ag | Inhibidores de autotaxina que comprenden un núcleo de anillo heteroaromático de bencil-amida cíclica |
| AU2016209906A1 (en) | 2015-01-20 | 2017-08-03 | Novartis Ag | PET imaging agents |
-
2016
- 2016-01-20 AU AU2016209906A patent/AU2016209906A1/en not_active Abandoned
- 2016-01-20 US US15/544,850 patent/US10450298B2/en active Active
- 2016-01-20 CA CA2974311A patent/CA2974311A1/en not_active Withdrawn
- 2016-01-20 KR KR1020177022757A patent/KR20170103960A/ko not_active Withdrawn
- 2016-01-20 MX MX2017009452A patent/MX2017009452A/es unknown
- 2016-01-20 ES ES16702985T patent/ES2828715T3/es active Active
- 2016-01-20 WO PCT/IB2016/050276 patent/WO2016116875A1/en not_active Ceased
- 2016-01-20 BR BR112017015455-2A patent/BR112017015455A2/pt not_active Application Discontinuation
- 2016-01-20 JP JP2017555866A patent/JP6723264B2/ja not_active Expired - Fee Related
- 2016-01-20 EP EP16702985.9A patent/EP3247706B1/en active Active
- 2016-01-20 CN CN201680016753.9A patent/CN107406419B/zh active Active
- 2016-01-20 EA EA201791643A patent/EA201791643A1/ru unknown
-
2019
- 2019-09-24 US US16/581,086 patent/US10865195B2/en active Active
-
2020
- 2020-06-22 JP JP2020106739A patent/JP2020158532A/ja active Pending
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