JP2018506287A5 - - Google Patents

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Publication number
JP2018506287A5
JP2018506287A5 JP2017542910A JP2017542910A JP2018506287A5 JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5 JP 2017542910 A JP2017542910 A JP 2017542910A JP 2017542910 A JP2017542910 A JP 2017542910A JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5
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JP
Japan
Prior art keywords
tcr
cells
purified
chain
nucleic acid
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JP2017542910A
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English (en)
Japanese (ja)
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JP7013240B2 (ja
JP2018506287A (ja
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Priority claimed from PCT/US2016/017521 external-priority patent/WO2016133779A1/en
Publication of JP2018506287A publication Critical patent/JP2018506287A/ja
Publication of JP2018506287A5 publication Critical patent/JP2018506287A5/ja
Priority to JP2022006072A priority Critical patent/JP7317158B2/ja
Application granted granted Critical
Publication of JP7013240B2 publication Critical patent/JP7013240B2/ja
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JP2017542910A 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体 Active JP7013240B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022006072A JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562116864P 2015-02-16 2015-02-16
US62/116,864 2015-02-16
PCT/US2016/017521 WO2016133779A1 (en) 2015-02-16 2016-02-11 A fully-human t cell receptor specific for the 369-377 epitope derived from the her2/neu (erbb2) receptor protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022006072A Division JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Publications (3)

Publication Number Publication Date
JP2018506287A JP2018506287A (ja) 2018-03-08
JP2018506287A5 true JP2018506287A5 (enExample) 2019-03-22
JP7013240B2 JP7013240B2 (ja) 2022-01-31

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ID=56692400

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017542910A Active JP7013240B2 (ja) 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体
JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Family Applications After (1)

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JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Country Status (6)

Country Link
US (3) US10414812B2 (enExample)
EP (2) EP3730515B1 (enExample)
JP (2) JP7013240B2 (enExample)
AU (4) AU2016220324B2 (enExample)
CA (1) CA2976656A1 (enExample)
WO (1) WO2016133779A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2557123B (en) 2015-07-31 2021-11-03 Univ Minnesota Modified cells and methods of therapy
IL302345B2 (en) 2016-10-07 2024-12-01 Enterome S A Immunogenic compounds for cancer therapy
WO2019006418A2 (en) 2017-06-30 2019-01-03 Intima Bioscience, Inc. ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
CN109776671B (zh) * 2017-11-14 2022-05-27 杭州康万达医药科技有限公司 分离的t细胞受体、其修饰的细胞、编码核酸、表达载体、制备方法、药物组合物和应用
CA3098128A1 (en) 2018-04-18 2019-10-24 Ucl Business Ltd Engineered regulatory t cell
WO2019241315A1 (en) 2018-06-12 2019-12-19 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
CN110857319B (zh) * 2018-08-24 2023-12-08 杭州康万达医药科技有限公司 一种分离的t细胞受体、其修饰的细胞、编码核酸及其应用
CA3154606A1 (en) * 2019-10-23 2021-04-29 Hans Stauss Engineered regulatory t cell

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US1975A (en) 1841-02-12 Manner of constructing corn-shellers
US4694778A (en) 1984-05-04 1987-09-22 Anicon, Inc. Chemical vapor deposition wafer boat
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
GB9125768D0 (en) 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
US6080840A (en) 1992-01-17 2000-06-27 Slanetz; Alfred E. Soluble T cell receptors
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
DE69433970T2 (de) 1993-08-10 2005-08-11 W.L. Gore & Associates, Inc., Newark Zelleinkapselungsvorrichtung
US5626561A (en) 1995-06-07 1997-05-06 Gore Hybrid Technologies, Inc. Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein
EP0773753B1 (en) 1995-06-07 2003-10-08 Gore Hybrid Technologies, Inc. An implantable containment apparatus for a therapeutical device
AU6854696A (en) 1995-09-22 1997-04-09 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
WO1997032603A1 (en) * 1996-03-05 1997-09-12 The Scripps Research Institute Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens
FR2827302B1 (fr) * 2001-07-13 2003-10-10 Genoway Cellule et animal transgenique modelisant la presentation antigenique humaine et leurs utilisations
US7213961B2 (en) 2003-07-11 2007-05-08 Hubbell Incorporated Low voltage luminaire assembly
CA2625403A1 (en) * 2005-10-17 2007-04-26 Institute For System Biology Tissue-and serum-derived glycoproteins and methods of their use
WO2010012829A1 (en) * 2008-07-31 2010-02-04 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Her2/neu specific t cell receptors
CA2751762A1 (en) * 2009-02-09 2010-08-12 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit U Nd Umwelt (Gmbh) Repertoire of allo-restricted peptide-specific t cell receptor sequences and use thereof
EP2618835B1 (en) * 2010-09-20 2017-07-05 BioNTech Cell & Gene Therapies GmbH Antigen-specific t cell receptors and t cell epitopes
EP2932264B1 (en) 2012-12-14 2019-01-30 BioNTech RNA Pharmaceuticals GmbH Novel mhc-independent tumor-associated antigens

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