JP2018506287A5 - - Google Patents

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Publication number
JP2018506287A5
JP2018506287A5 JP2017542910A JP2017542910A JP2018506287A5 JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5 JP 2017542910 A JP2017542910 A JP 2017542910A JP 2017542910 A JP2017542910 A JP 2017542910A JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5
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JP
Japan
Prior art keywords
tcr
cells
purified
chain
nucleic acid
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Application number
JP2017542910A
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English (en)
Japanese (ja)
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JP7013240B2 (ja
JP2018506287A (ja
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Priority claimed from PCT/US2016/017521 external-priority patent/WO2016133779A1/en
Publication of JP2018506287A publication Critical patent/JP2018506287A/ja
Publication of JP2018506287A5 publication Critical patent/JP2018506287A5/ja
Priority to JP2022006072A priority Critical patent/JP7317158B2/ja
Application granted granted Critical
Publication of JP7013240B2 publication Critical patent/JP7013240B2/ja
Active legal-status Critical Current
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JP2017542910A 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体 Active JP7013240B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022006072A JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562116864P 2015-02-16 2015-02-16
US62/116,864 2015-02-16
PCT/US2016/017521 WO2016133779A1 (en) 2015-02-16 2016-02-11 A fully-human t cell receptor specific for the 369-377 epitope derived from the her2/neu (erbb2) receptor protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022006072A Division JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Publications (3)

Publication Number Publication Date
JP2018506287A JP2018506287A (ja) 2018-03-08
JP2018506287A5 true JP2018506287A5 (enExample) 2019-03-22
JP7013240B2 JP7013240B2 (ja) 2022-01-31

Family

ID=56692400

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017542910A Active JP7013240B2 (ja) 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体
JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Country Status (6)

Country Link
US (4) US10414812B2 (enExample)
EP (2) EP3259284B1 (enExample)
JP (2) JP7013240B2 (enExample)
AU (4) AU2016220324B2 (enExample)
CA (1) CA2976656A1 (enExample)
WO (1) WO2016133779A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
EP4339287A3 (en) 2015-07-31 2024-05-22 Regents Of The University Of Minnesota Modified cells and methods of therapy
IL296165B2 (en) 2016-10-07 2023-10-01 Enterome S A Immunogenic compounds for cancer treatment
CN111511375A (zh) 2017-06-30 2020-08-07 因提玛生物科学公司 用于基因治疗的腺相关病毒载体
CN109776671B (zh) * 2017-11-14 2022-05-27 杭州康万达医药科技有限公司 分离的t细胞受体、其修饰的细胞、编码核酸、表达载体、制备方法、药物组合物和应用
US12227756B2 (en) * 2018-04-18 2025-02-18 Ucl Business Ltd Engineered regulatory T cell
US20220403001A1 (en) 2018-06-12 2022-12-22 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
CN110857319B (zh) * 2018-08-24 2023-12-08 杭州康万达医药科技有限公司 一种分离的t细胞受体、其修饰的细胞、编码核酸及其应用
AU2020370033A1 (en) 2019-10-23 2022-06-02 Ucl Business Ltd Engineered regulatory T cell
GB201915359D0 (en) 2019-10-23 2019-12-04 Ucl Business Ltd Engineered regulatory t cell

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US1975A (en) 1841-02-12 Manner of constructing corn-shellers
US4694778A (en) 1984-05-04 1987-09-22 Anicon, Inc. Chemical vapor deposition wafer boat
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
GB9125768D0 (en) 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
US6080840A (en) 1992-01-17 2000-06-27 Slanetz; Alfred E. Soluble T cell receptors
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
DE69433970T2 (de) 1993-08-10 2005-08-11 W.L. Gore & Associates, Inc., Newark Zelleinkapselungsvorrichtung
US5626561A (en) 1995-06-07 1997-05-06 Gore Hybrid Technologies, Inc. Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein
JPH10503964A (ja) 1995-06-07 1998-04-14 ゴア ハイブリッド テクノロジーズ，インコーポレイティド 治療用デバイスのための移植可能な閉じ込め装置並びにその中にそのデバイスを装填及び再装填する方法
AU6854696A (en) 1995-09-22 1997-04-09 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
EP0910409A4 (en) * 1996-03-05 2003-03-19 Scripps Research Inst RECOMBINANT GENE CONSTRUCTS ENCODING T-CELL RECEPTORS SPECIFIC TO HUMAN-RESTRICTED TUMORANTANTIGENS
FR2827302B1 (fr) * 2001-07-13 2003-10-10 Genoway Cellule et animal transgenique modelisant la presentation antigenique humaine et leurs utilisations
US7213961B2 (en) 2003-07-11 2007-05-08 Hubbell Incorporated Low voltage luminaire assembly
WO2007047796A2 (en) * 2005-10-17 2007-04-26 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
EP2318434A1 (en) 2008-07-31 2011-05-11 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Her2/neu specific t cell receptors
WO2010089412A1 (en) * 2009-02-09 2010-08-12 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) Repertoire of allo-restricted peptide-specific t cell receptor sequences and use thereof
ES2635335T3 (es) * 2010-09-20 2017-10-03 Biontech Cell & Gene Therapies Gmbh Receptores de células T específicos de antígeno y epítopos de células T
SI2932264T1 (sl) 2012-12-14 2019-05-31 Biontech Rna Pharmaceuticals Gmbh Novi MHC-neodvisni, s tumorjem povezani antigeni

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