JP2018504896A5 - - Google Patents
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- JP2018504896A5 JP2018504896A5 JP2017533828A JP2017533828A JP2018504896A5 JP 2018504896 A5 JP2018504896 A5 JP 2018504896A5 JP 2017533828 A JP2017533828 A JP 2017533828A JP 2017533828 A JP2017533828 A JP 2017533828A JP 2018504896 A5 JP2018504896 A5 JP 2018504896A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- peptide
- nanoparticle
- nanoparticles
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1403004 | 2014-12-24 | ||
| FR14/03004 | 2014-12-24 | ||
| PCT/EP2015/081197 WO2016102687A1 (en) | 2014-12-24 | 2015-12-23 | Peptides and nanoparticles for intracellular delivery of molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018504896A JP2018504896A (ja) | 2018-02-22 |
| JP2018504896A5 true JP2018504896A5 (https=) | 2019-02-14 |
| JP6768664B2 JP6768664B2 (ja) | 2020-10-14 |
Family
ID=55174604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533828A Active JP6768664B2 (ja) | 2014-12-24 | 2015-12-23 | 分子の細胞内送達のためのペプチドおよびナノ粒子 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10745440B2 (https=) |
| EP (2) | EP3237436B1 (https=) |
| JP (1) | JP6768664B2 (https=) |
| CN (1) | CN107548401A (https=) |
| AU (1) | AU2015370926B2 (https=) |
| CA (1) | CA2971643C (https=) |
| CY (1) | CY1121868T1 (https=) |
| DK (1) | DK3237436T3 (https=) |
| ES (1) | ES2743188T3 (https=) |
| HR (1) | HRP20191400T1 (https=) |
| HU (1) | HUE046054T2 (https=) |
| IL (1) | IL252810B (https=) |
| LT (1) | LT3237436T (https=) |
| MX (1) | MX387665B (https=) |
| PL (1) | PL3237436T3 (https=) |
| PT (1) | PT3237436T (https=) |
| WO (1) | WO2016102687A1 (https=) |
| ZA (1) | ZA201704364B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014053879A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053880A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| EP3237436B1 (en) | 2014-12-24 | 2019-05-01 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of molecules |
| AU2017268842B2 (en) | 2016-05-27 | 2022-08-11 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of genome-editing molecules |
| JP2020500031A (ja) * | 2016-10-11 | 2020-01-09 | ミネルバ バイオテクノロジーズ コーポレーション | ヒト化抗ｍｕｃ１＊抗体及び開裂酵素の使用 |
| EP3581190B1 (en) | 2016-12-09 | 2021-03-10 | ONK Therapeutics Limited | Engineered natural killer cells and uses thereof |
| EP3665285A4 (en) * | 2017-08-10 | 2021-08-11 | Aadigen, LLC | PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR VIRUS ADMINISTRATION |
| CN109557067B (zh) * | 2017-09-26 | 2021-07-20 | 中国科学院烟台海岸带研究所 | 一种核—卫星结构金纳米颗粒及其制备方法 |
| US20200323964A1 (en) * | 2017-10-16 | 2020-10-15 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of mrna |
| CN108424437B (zh) * | 2018-02-08 | 2021-06-22 | 青岛农业大学 | 一种递送分子及纳米颗粒、制备方法、用途 |
| IL280120B2 (en) * | 2018-08-07 | 2025-04-01 | Eth Zuerich | Polypeptides that self-assemble into nanoparticles |
| MX2021012740A (es) | 2019-04-17 | 2022-01-24 | Aadigen Llc | Péptidos y nanopartículas para entrega intracelular de moléculas. |
| KR102146392B1 (ko) * | 2019-06-11 | 2020-08-21 | 한림대학교 산학협력단 | 포스포글리세레이트 뮤테이즈 1 융합단백질 및 이를 포함하는 약학 조성물 |
| CN110540992B (zh) * | 2019-08-21 | 2021-02-09 | 武汉泽智生物医药有限公司 | 增强靶基因沉默效率的siRNA分子及其应用 |
| WO2021080955A1 (en) | 2019-10-21 | 2021-04-29 | Celgene Corporation | Substituted 4-aminoisoindoline-1,3-dione compounds and second active agents for combined use |
| CN111732635B (zh) * | 2020-06-22 | 2022-03-22 | 中国医学科学院基础医学研究所 | 与cd123蛋白特异性结合的多肽、多肽复合物、共递送系统及其制备方法与应用 |
| CN116724059A (zh) | 2020-07-24 | 2023-09-08 | 阿迪根有限公司 | 用于治疗病毒感染的组合物和方法 |
| CN113563429A (zh) * | 2021-07-19 | 2021-10-29 | 天津大学 | 一种基于烷基化多肽的核酸递送系统及制备方法与应用 |
| US20250295806A1 (en) * | 2022-05-05 | 2025-09-25 | Case Western Reserve University | Immunostimulatory nanoparticle |
| US20240366521A1 (en) * | 2023-01-17 | 2024-11-07 | Qana Therapeutics Inc. | Nanoparticles and methods of use |
| WO2024187174A2 (en) | 2023-03-09 | 2024-09-12 | Aadigen, Llc | Compositions for treating cancer with kras mutations and uses thereof |
| WO2025059215A1 (en) | 2023-09-12 | 2025-03-20 | Aadigen, Llc | Methods and compositions for treating or preventing cancer |
| WO2025193628A2 (en) | 2024-03-09 | 2025-09-18 | Aadigen, Llc | Compositions for treating cancer with kras mutations and uses thereof |
| WO2025193917A1 (en) * | 2024-03-14 | 2025-09-18 | Day Emily | Antibody and sirna nanocarriers and uses thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994004958A1 (en) | 1992-08-25 | 1994-03-03 | Merck Patent Gmbh | Paper white pdlc system |
| US7514530B2 (en) | 2004-04-26 | 2009-04-07 | Centre National De La Recherche Scientifique | Peptide carrier for delivering siRNA into mammalian cells |
| GB0513096D0 (en) | 2005-06-28 | 2005-08-03 | Strathclyde | Treatment of microbial infections |
| EP1969000A2 (en) | 2005-12-06 | 2008-09-17 | Centre National de la Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| DE602005025141D1 (de) | 2005-12-06 | 2011-01-13 | Centre Nat Rech Scient | In Zellen eindringende Peptide als Träger für Moleküle |
| US7579318B2 (en) | 2005-12-06 | 2009-08-25 | Centre De La Recherche De La Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2008036929A2 (en) | 2006-09-21 | 2008-03-27 | Alnylam Pharmaceuticals, Inc. | Complex for transferring an anionic substance into a cell |
| CA2725227A1 (en) | 2008-05-06 | 2009-11-12 | Asim Kumar Debnath | Antiviral cell penetrating peptides |
| EP4032552B1 (en) | 2008-08-26 | 2023-10-04 | City of Hope | Method and compositions for enhanced anti-tumor effector functioning of t cells |
| WO2012137036A1 (en) | 2011-04-04 | 2012-10-11 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| JP2015509085A (ja) * | 2012-01-01 | 2015-03-26 | キュービーアイ エンタープライゼズ リミテッドＱｂｉ Ｅｎｔｅｒｐｒｉｓｅｓ Ｌｔｄ． | 治療剤および診断剤の選択的送達のためのｅｎｄｏ１８０を標的とする粒子 |
| WO2013150338A1 (en) * | 2012-04-04 | 2013-10-10 | Centre National De La Recherche Scientifique | Stapled cell penetrating peptides for intracellular delivery of molecules |
| EA033110B1 (ru) | 2012-04-11 | 2019-08-30 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерный рецептор антигена, направленный на антиген созревания b-клеток, кодирующая его нуклеиновая кислота, соответствующие экспрессионный вектор, клетка-хозяин, применения и способы |
| US20150080320A1 (en) | 2012-05-16 | 2015-03-19 | Aadigen, Llc | Multi-target modulation for treating fibrosis and inflammatory conditions |
| WO2014053880A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053881A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053879A1 (en) * | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053882A1 (en) * | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014099671A1 (en) | 2012-12-20 | 2014-06-26 | Bluebird Bio, Inc. | Chimeric antigen receptors and immune cells targeting b cell malignancies |
| EP4303232A3 (en) | 2013-02-15 | 2024-04-17 | The Regents of The University of California | Chimeric antigen receptor and methods of use thereof |
| EP3237436B1 (en) | 2014-12-24 | 2019-05-01 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of molecules |
-
2015
- 2015-12-23 EP EP15825938.2A patent/EP3237436B1/en active Active
- 2015-12-23 ES ES15825938T patent/ES2743188T3/es active Active
- 2015-12-23 EP EP19163255.3A patent/EP3556768A1/en not_active Withdrawn
- 2015-12-23 HR HRP20191400 patent/HRP20191400T1/hr unknown
- 2015-12-23 HU HUE15825938A patent/HUE046054T2/hu unknown
- 2015-12-23 LT LTEP15825938.2T patent/LT3237436T/lt unknown
- 2015-12-23 CN CN201580076607.0A patent/CN107548401A/zh active Pending
- 2015-12-23 CA CA2971643A patent/CA2971643C/en active Active
- 2015-12-23 WO PCT/EP2015/081197 patent/WO2016102687A1/en not_active Ceased
- 2015-12-23 PT PT15825938T patent/PT3237436T/pt unknown
- 2015-12-23 US US15/539,619 patent/US10745440B2/en active Active
- 2015-12-23 MX MX2017007919A patent/MX387665B/es unknown
- 2015-12-23 PL PL15825938T patent/PL3237436T3/pl unknown
- 2015-12-23 AU AU2015370926A patent/AU2015370926B2/en active Active
- 2015-12-23 DK DK15825938.2T patent/DK3237436T3/da active
- 2015-12-23 JP JP2017533828A patent/JP6768664B2/ja active Active
-
2017
- 2017-06-11 IL IL252810A patent/IL252810B/en unknown
- 2017-06-27 ZA ZA2017/04364A patent/ZA201704364B/en unknown
-
2019
- 2019-08-01 CY CY20191100822T patent/CY1121868T1/el unknown
-
2020
- 2020-07-15 US US16/930,091 patent/US11713336B2/en active Active
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