JP2018504446A - がんを処置するためのｈｓｐ９０阻害剤およびｐｄ−１阻害剤の組み合わせ治療 - Google Patents

がんを処置するためのｈｓｐ９０阻害剤およびｐｄ−１阻害剤の組み合わせ治療 Download PDF

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JP2018504446A
JP2018504446A JP2017541796A JP2017541796A JP2018504446A JP 2018504446 A JP2018504446 A JP 2018504446A JP 2017541796 A JP2017541796 A JP 2017541796A JP 2017541796 A JP2017541796 A JP 2017541796A JP 2018504446 A JP2018504446 A JP 2018504446A
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cancer
inhibitor
hydroxy
hsp90
indol
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JP2018504446A5 (enExample
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デイビッド エー． プロイア，
デイビッド エー． プロイア，
パトリシア イー． ラオ，
パトリシア イー． ラオ，
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シンタ ファーマシューティカルズ コーポレーション
シンタ ファーマシューティカルズ コーポレーション
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017541796A 2015-02-09 2016-02-09 がんを処置するためのｈｓｐ９０阻害剤およびｐｄ−１阻害剤の組み合わせ治療 Pending JP2018504446A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113807P 2015-02-09 2015-02-09
US62/113,807 2015-02-09
PCT/US2016/017075 WO2016130502A1 (en) 2015-02-09 2016-02-09 Combination therapy of hsp90 inhibitors and pd-1 inhibitors for treating cancer

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JP2018504446A true JP2018504446A (ja) 2018-02-15
JP2018504446A5 JP2018504446A5 (enExample) 2019-03-07

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US (1) US11497733B2 (enExample)
EP (1) EP3256161A1 (enExample)
JP (1) JP2018504446A (enExample)
KR (1) KR20170113664A (enExample)
CN (1) CN107645957A (enExample)
AU (1) AU2016219497A1 (enExample)
BR (1) BR112017016973A2 (enExample)
CA (1) CA2976072A1 (enExample)
HK (1) HK1244436A1 (enExample)
IL (1) IL253905A0 (enExample)
MX (1) MX2017010299A (enExample)
WO (1) WO2016130502A1 (enExample)

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CA2974651A1 (en) 2014-01-24 2015-07-30 Children's Hospital Of Eastern Ontario Research Institute Inc. Smc combination therapy for the treatment of cancer
CN110769857A (zh) * 2017-06-20 2020-02-07 塔弗达治疗有限公司 包含靶向治疗剂的联合疗法
TWI855994B (zh) * 2017-06-30 2024-09-21 日商大鵬藥品工業股份有限公司 使用氮雜雙環式化合物之癌化學療法
US11407831B2 (en) * 2017-10-30 2022-08-09 Ube Industries, Ltd. Pharmaceutical composition administered in combination with substituted dihydropyrrolopyrazole compound and immunotherapeutic agent
CN112292126A (zh) * 2018-06-01 2021-01-29 塔弗达治疗有限公司 联合疗法
EP3878446A1 (en) * 2020-03-09 2021-09-15 Universite De Geneve Hsd11b1 inhibitors for use in immunotherapy and uses thereof
US20250281609A1 (en) * 2021-10-19 2025-09-11 Organoidsciences Ltd. Composition for treating or preventing cancer

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WO2013173223A1 (en) * 2012-05-15 2013-11-21 Bristol-Myers Squibb Company Cancer immunotherapy by disrupting pd-1/pd-l1 signaling

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US11497733B2 (en) 2022-11-15
BR112017016973A2 (pt) 2018-04-03
CN107645957A (zh) 2018-01-30
IL253905A0 (en) 2017-10-31
AU2016219497A1 (en) 2017-08-31
US20180064689A1 (en) 2018-03-08
CA2976072A1 (en) 2016-08-18
EP3256161A1 (en) 2017-12-20
MX2017010299A (es) 2017-11-10
KR20170113664A (ko) 2017-10-12
WO2016130502A1 (en) 2016-08-18
HK1244436A1 (zh) 2018-08-10

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