JP2018504446A - がんを処置するためのhsp90阻害剤およびpd−1阻害剤の組み合わせ治療 - Google Patents

がんを処置するためのhsp90阻害剤およびpd−1阻害剤の組み合わせ治療 Download PDF

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JP2018504446A
JP2018504446A JP2017541796A JP2017541796A JP2018504446A JP 2018504446 A JP2018504446 A JP 2018504446A JP 2017541796 A JP2017541796 A JP 2017541796A JP 2017541796 A JP2017541796 A JP 2017541796A JP 2018504446 A JP2018504446 A JP 2018504446A
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cancer
inhibitor
hydroxy
hsp90
indol
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JP2018504446A5 (enExample
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デイビッド エー. プロイア,
デイビッド エー. プロイア,
パトリシア イー. ラオ,
パトリシア イー. ラオ,
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シンタ ファーマシューティカルズ コーポレーション
シンタ ファーマシューティカルズ コーポレーション
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017541796A 2015-02-09 2016-02-09 がんを処置するためのhsp90阻害剤およびpd−1阻害剤の組み合わせ治療 Pending JP2018504446A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113807P 2015-02-09 2015-02-09
US62/113,807 2015-02-09
PCT/US2016/017075 WO2016130502A1 (en) 2015-02-09 2016-02-09 Combination therapy of hsp90 inhibitors and pd-1 inhibitors for treating cancer

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JP2018504446A true JP2018504446A (ja) 2018-02-15
JP2018504446A5 JP2018504446A5 (enExample) 2019-03-07

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US (1) US11497733B2 (enExample)
EP (1) EP3256161A1 (enExample)
JP (1) JP2018504446A (enExample)
KR (1) KR20170113664A (enExample)
CN (1) CN107645957A (enExample)
AU (1) AU2016219497A1 (enExample)
BR (1) BR112017016973A2 (enExample)
CA (1) CA2976072A1 (enExample)
HK (1) HK1244436A1 (enExample)
IL (1) IL253905A0 (enExample)
MX (1) MX2017010299A (enExample)
WO (1) WO2016130502A1 (enExample)

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WO2015109391A1 (en) 2014-01-24 2015-07-30 Children's Hospital Of Eastern Ontario Research Institute Inc. Smc combination therapy for the treatment of cancer
CA3067454A1 (en) * 2017-06-20 2018-12-27 Tarveda Therapeutics, Inc. Combination therapies comprising targeted therapeutics
FI3646869T3 (fi) * 2017-06-30 2025-09-17 Taiho Pharmaceutical Co Ltd Solunsalpaajahoito atsabisykloyhdisteellä syövän hoitamiseksi
WO2019088016A1 (ja) * 2017-10-30 2019-05-09 宇部興産株式会社 置換ジヒドロピロロピラゾール化合物および免疫療法剤が組み合わせて投与される医薬組成物
JP2021525766A (ja) * 2018-06-01 2021-09-27 ターベダ セラピューティクス インコーポレイテッドTarveda Therapeutics,Inc. 併用療法
EP3878446A1 (en) * 2020-03-09 2021-09-15 Universite De Geneve Hsd11b1 inhibitors for use in immunotherapy and uses thereof
KR20230055998A (ko) * 2021-10-19 2023-04-26 오가노이드사이언스 주식회사 암 치료 또는 예방용 조성물

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JP2014520808A (ja) * 2011-07-07 2014-08-25 シンタ ファーマシューティカルズ コーポレーション Hsp90阻害化合物を用いた癌の治療

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AU2016219497A1 (en) 2017-08-31
WO2016130502A1 (en) 2016-08-18
KR20170113664A (ko) 2017-10-12
IL253905A0 (en) 2017-10-31
US11497733B2 (en) 2022-11-15
MX2017010299A (es) 2017-11-10
BR112017016973A2 (pt) 2018-04-03
HK1244436A1 (zh) 2018-08-10
CN107645957A (zh) 2018-01-30
CA2976072A1 (en) 2016-08-18
US20180064689A1 (en) 2018-03-08
EP3256161A1 (en) 2017-12-20

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