JP2018502600A5 - - Google Patents

Info

Publication number

JP2018502600A5

JP2018502600A5 JP2017552233A JP2017552233A JP2018502600A5 JP 2018502600 A5 JP2018502600 A5 JP 2018502600A5 JP 2017552233 A JP2017552233 A JP 2017552233A JP 2017552233 A JP2017552233 A JP 2017552233A JP 2018502600 A5 JP2018502600 A5 JP 2018502600A5

Authority

JP

Japan

Prior art keywords

lactic acid

plasmid

seq

amino acid

kit

Prior art date

2015-12-23

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 40
• 239000013612 plasmid Substances 0.000 claims 22
• 235000014655 lactic acid Nutrition 0.000 claims 20
• 239000004310 lactic acid Substances 0.000 claims 20
• 241000894006 Bacteria Species 0.000 claims 14
• 125000003275 alpha amino acid group Chemical group 0.000 claims 12
• 108090000623 proteins and genes Proteins 0.000 claims 9
• 102000004169 proteins and genes Human genes 0.000 claims 9
• 239000002773 nucleotide Substances 0.000 claims 6
• 125000003729 nucleotide group Chemical group 0.000 claims 6
• 206010052428 Wound Diseases 0.000 claims 5
• 208000027418 Wounds and injury Diseases 0.000 claims 5
• 230000001939 inductive effect Effects 0.000 claims 5
• 239000008194 pharmaceutical composition Substances 0.000 claims 5
• 101000889048 Homo sapiens C-X-C motif chemokine 17 Proteins 0.000 claims 3
• 241001529936 Murinae Species 0.000 claims 3
• 101100167135 Mus musculus Chil3 gene Proteins 0.000 claims 3
• 239000000411 inducer Substances 0.000 claims 3
• 230000001105 regulatory effect Effects 0.000 claims 3
• 102100039435 C-X-C motif chemokine 17 Human genes 0.000 claims 2
• 108700009548 Lactobacillus sakacin P Proteins 0.000 claims 2
• 241001465754 Metazoa Species 0.000 claims 2
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
• VMETVXNVLXCEFC-UHFFFAOYSA-N Sakacin P Chemical compound NC(=O)C(=O)C(C)NC(=O)OC(C)(C)C VMETVXNVLXCEFC-UHFFFAOYSA-N 0.000 claims 2
• 230000001580 bacterial effect Effects 0.000 claims 2
• 230000035876 healing Effects 0.000 claims 2
• 239000007788 liquid Substances 0.000 claims 2
• 230000029663 wound healing Effects 0.000 claims 2
• 108020004705 Codon Proteins 0.000 claims 1
• 101000617130 Homo sapiens Stromal cell-derived factor 1 Proteins 0.000 claims 1
• 241000186660 Lactobacillus Species 0.000 claims 1
• 241000186604 Lactobacillus reuteri Species 0.000 claims 1
• 108010053775 Nisin Proteins 0.000 claims 1
• NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims 1
• ACQJWVPNGVNRCD-UHFFFAOYSA-N Sakacin A Chemical compound CC(C)(C)N(C)C(=O)NC(C)NC(=O)C(N)CC(O)=O ACQJWVPNGVNRCD-UHFFFAOYSA-N 0.000 claims 1
• 206010072170 Skin wound Diseases 0.000 claims 1
• 102100021669 Stromal cell-derived factor 1 Human genes 0.000 claims 1
• 102000055279 human CXCL17 Human genes 0.000 claims 1
• 229940039696 lactobacillus Drugs 0.000 claims 1
• 229940001882 lactobacillus reuteri Drugs 0.000 claims 1
• 239000004309 nisin Substances 0.000 claims 1
• 235000010297 nisin Nutrition 0.000 claims 1
• 239000000825 pharmaceutical preparation Substances 0.000 claims 1
• 229940127557 pharmaceutical product Drugs 0.000 claims 1
• 108010027327 sakacin A Proteins 0.000 claims 1