JP2018500390A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018500390A5 JP2018500390A5 JP2017549860A JP2017549860A JP2018500390A5 JP 2018500390 A5 JP2018500390 A5 JP 2018500390A5 JP 2017549860 A JP2017549860 A JP 2017549860A JP 2017549860 A JP2017549860 A JP 2017549860A JP 2018500390 A5 JP2018500390 A5 JP 2018500390A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- wnt5a
- tumor
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090029P | 2014-12-10 | 2014-12-10 | |
| US62/090,029 | 2014-12-10 | ||
| PCT/IB2015/002577 WO2016092378A1 (en) | 2014-12-10 | 2015-12-09 | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500390A JP2018500390A (ja) | 2018-01-11 |
| JP2018500390A5 true JP2018500390A5 (https=) | 2019-01-24 |
| JP6921755B2 JP6921755B2 (ja) | 2021-08-18 |
Family
ID=55353245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017549860A Active JP6921755B2 (ja) | 2014-12-10 | 2015-12-09 | 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10688167B2 (https=) |
| EP (1) | EP3229831B1 (https=) |
| JP (1) | JP6921755B2 (https=) |
| KR (1) | KR102674191B1 (https=) |
| AU (1) | AU2015359043C1 (https=) |
| CA (1) | CA2970140A1 (https=) |
| DK (1) | DK3229831T3 (https=) |
| ES (1) | ES2796973T3 (https=) |
| WO (1) | WO2016092378A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10852069B2 (en) | 2010-05-04 | 2020-12-01 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a fractal heat sink |
| WO2016092378A1 (en) * | 2014-12-10 | 2016-06-16 | Angelo Luigi Vescovi | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
| WO2019081657A1 (en) * | 2017-10-25 | 2019-05-02 | Wntresearch Ab | WNT5A PEPTIDES FOR REDUCING CANCER STEM CELLS |
| KR101921836B1 (ko) | 2017-11-23 | 2018-11-26 | 서울대학교병원 | 피부성체 줄기세포의 분화 조절 방법, 및 피부성체 줄기세포의 분화 조절용 조성물 및 키트 |
| EP3784240B1 (en) * | 2018-04-24 | 2023-09-20 | Universidade do Minho | Wnt6 as glioblastoma oncogenic biomarker, and uses of inhibitors thereof for treating wnt6-overexpressing glioblastoma |
| EP3613757A1 (en) * | 2018-08-20 | 2020-02-26 | Wntresearch AB | Solution phase routes for wnt hexapeptides |
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| KR20220050835A (ko) * | 2019-04-16 | 2022-04-25 | 더블유엔티리서치 에이비 | 암 치료에 사용하기 위한 면역 체크포인트 억제제와 조합된 펩타이드 |
| WO2021034784A1 (en) | 2019-08-16 | 2021-02-25 | Poltorak Technologies, LLC | Device and method for medical diagnostics |
| CN114081954B (zh) * | 2021-10-30 | 2023-02-28 | 中国人民解放军陆军军医大学第一附属医院 | 用于胶质母细胞瘤治疗的药物组合物以及预后的诊断试剂 |
| CN116173048A (zh) * | 2023-01-19 | 2023-05-30 | 温州医科大学附属第一医院 | 棉子糖及其衍生物在胶质母细胞瘤治疗中的应用 |
| WO2025088835A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人大阪大学 | ヒト化抗ｃｋａｐ４抗体又はその抗原結合性断片 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| GB2129691B (en) | 1982-10-08 | 1987-08-05 | Glaxo Group Ltd | Devices for administering medicaments to patients |
| AU591152B2 (en) | 1985-07-30 | 1989-11-30 | Glaxo Group Limited | Devices for administering medicaments to patients |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP1226172A1 (en) | 1999-11-05 | 2002-07-31 | Forskarpatent i Syd AB | Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis |
| DK1888628T3 (da) * | 2005-05-30 | 2015-02-02 | Wntres Ab | En peptidligand til forstyrrelse af cancercellemigration |
| EP2328604B1 (en) | 2008-08-13 | 2014-10-08 | Wntresearch AB | The use of wnt5-a peptide derivates for the treatment of melanoma and gastric cancer |
| AU2011205409B2 (en) | 2010-01-12 | 2015-08-20 | Oncomed Pharmaceuticals, Inc. | Wnt-binding agents and uses thereof |
| EP2446895A1 (en) | 2010-10-01 | 2012-05-02 | Stemgen S.P.A. | EPH receptor expression in tumor stem cells |
| WO2013006129A1 (en) * | 2011-07-01 | 2013-01-10 | Wntresearch Ab | Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients |
| US20140171356A1 (en) | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| WO2016092378A1 (en) * | 2014-12-10 | 2016-06-16 | Angelo Luigi Vescovi | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
-
2015
- 2015-12-09 WO PCT/IB2015/002577 patent/WO2016092378A1/en not_active Ceased
- 2015-12-09 EP EP15834638.7A patent/EP3229831B1/en active Active
- 2015-12-09 CA CA2970140A patent/CA2970140A1/en active Pending
- 2015-12-09 KR KR1020177018938A patent/KR102674191B1/ko active Active
- 2015-12-09 AU AU2015359043A patent/AU2015359043C1/en active Active
- 2015-12-09 ES ES15834638T patent/ES2796973T3/es active Active
- 2015-12-09 JP JP2017549860A patent/JP6921755B2/ja active Active
- 2015-12-09 DK DK15834638.7T patent/DK3229831T3/da active
- 2015-12-09 US US15/533,842 patent/US10688167B2/en active Active
-
2020
- 2020-05-13 US US15/931,081 patent/US11357840B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018500390A5 (https=) | ||
| Ramer et al. | Restoring function after spinal cord injury: towards clinical translation of experimental strategies | |
| Shi et al. | Collagen scaffolds modified with collagen-binding bFGF promotes the neural regeneration in a rat hemisected spinal cord injury model | |
| Kim et al. | Dopaminergic pathway reconstruction by Akt/Rheb‐induced axon regeneration | |
| JP2020040969A5 (https=) | ||
| Lee et al. | The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease | |
| SA521421559B1 (ar) | أجهزة قابلة للزرع للعلاج بالخلايا وطرق ذات الصلة | |
| MX2010003774A (es) | Formulaciones oftalmicas acuosas. | |
| NZ610556A (en) | Stem cell suspension | |
| KR101749138B1 (ko) | 신경질환 예방 또는 치료를 위한 aimp2-dx2를 포함하는 약학 조성물 및 이의 용도 | |
| RU2010135532A (ru) | Лечение и предупреждение болезней сердца с использованием двух или более изоформ фактора роста гепатоцидов | |
| KR20190120197A (ko) | 치료 및 신경보호 펩티드 | |
| Ji et al. | Decellularized matrix of adipose-derived mesenchymal stromal cells enhanced retinal progenitor cell proliferation via the Akt/Erk pathway and neuronal differentiation | |
| Nakhaeifard et al. | Conditioned medium protects dopaminergic neurons in parkinsonian rats | |
| CA2797858A1 (en) | Sox9 inhibitors | |
| JP6841871B2 (ja) | 転移を阻害し、線維症を処置し、かつ創傷の治癒を向上させる方法および組成物 | |
| He et al. | Bone marrow stromal cells promote neuroplasticity of cerebral ischemic rats via a phosphorylated CRMP2-mediated mechanism | |
| WO2018039100A2 (en) | Stem cell-produced microvesicles for treating tendon pathologies | |
| CN106222173A (zh) | circRNA MNCR核苷酸、含有该核苷酸的药物组合物及其用途 | |
| Smith et al. | Amphetamine-induced dyskinesia in the transplanted hemi-parkinsonian mouse | |
| Hettiaratchi et al. | Recent advances in regenerative medicine approaches for spinal cord injuries | |
| NZ732532A (en) | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors | |
| NZ732532B2 (en) | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors | |
| Omar Khudhur et al. | Epothilone B loaded in acellular nerve allograft enhanced sciatic nerve regeneration in rats | |
| MX2021007410A (es) | Proteina de fusion que comprende variantes de la proteina lefty a humana y el uso de estas. |