DK3229831T3 - Fremgangsmåder og sammensætninger til reduktion af vækst, migration og invasivitet af hjernecancerstamceller og forbedring af overlevelsen for patienter med hjernetumorer - Google Patents
Fremgangsmåder og sammensætninger til reduktion af vækst, migration og invasivitet af hjernecancerstamceller og forbedring af overlevelsen for patienter med hjernetumorer Download PDFInfo
- Publication number
- DK3229831T3 DK3229831T3 DK15834638.7T DK15834638T DK3229831T3 DK 3229831 T3 DK3229831 T3 DK 3229831T3 DK 15834638 T DK15834638 T DK 15834638T DK 3229831 T3 DK3229831 T3 DK 3229831T3
- Authority
- DK
- Denmark
- Prior art keywords
- invasiveness
- migration
- patients
- growth
- compositions
- Prior art date
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 230000005012 migration Effects 0.000 title 1
- 238000013508 migration Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
- 230000004083 survival effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090029P | 2014-12-10 | 2014-12-10 | |
| PCT/IB2015/002577 WO2016092378A1 (en) | 2014-12-10 | 2015-12-09 | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3229831T3 true DK3229831T3 (da) | 2020-06-15 |
Family
ID=55353245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15834638.7T DK3229831T3 (da) | 2014-12-10 | 2015-12-09 | Fremgangsmåder og sammensætninger til reduktion af vækst, migration og invasivitet af hjernecancerstamceller og forbedring af overlevelsen for patienter med hjernetumorer |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10688167B2 (https=) |
| EP (1) | EP3229831B1 (https=) |
| JP (1) | JP6921755B2 (https=) |
| KR (1) | KR102674191B1 (https=) |
| AU (1) | AU2015359043C1 (https=) |
| CA (1) | CA2970140A1 (https=) |
| DK (1) | DK3229831T3 (https=) |
| ES (1) | ES2796973T3 (https=) |
| WO (1) | WO2016092378A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10852069B2 (en) | 2010-05-04 | 2020-12-01 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a fractal heat sink |
| JP6921755B2 (ja) * | 2014-12-10 | 2021-08-18 | ハイパーステム ソシエテ アノニム | 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物 |
| WO2019081657A1 (en) * | 2017-10-25 | 2019-05-02 | Wntresearch Ab | WNT5A PEPTIDES FOR REDUCING CANCER STEM CELLS |
| KR101921836B1 (ko) | 2017-11-23 | 2018-11-26 | 서울대학교병원 | 피부성체 줄기세포의 분화 조절 방법, 및 피부성체 줄기세포의 분화 조절용 조성물 및 키트 |
| EP3784240B1 (en) * | 2018-04-24 | 2023-09-20 | Universidade do Minho | Wnt6 as glioblastoma oncogenic biomarker, and uses of inhibitors thereof for treating wnt6-overexpressing glioblastoma |
| EP3613757A1 (en) * | 2018-08-20 | 2020-02-26 | Wntresearch AB | Solution phase routes for wnt hexapeptides |
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| SG11202111476RA (en) * | 2019-04-16 | 2021-11-29 | Wntresearch Ab | Peptides in combination with immune checkpoint inhibitors for use in treatment of cancer |
| EP4013297A4 (en) | 2019-08-16 | 2023-12-13 | Poltorak Technologies, LLC | DEVICE AND METHOD FOR MEDICAL DIAGNOSTICS |
| CN114081954B (zh) * | 2021-10-30 | 2023-02-28 | 中国人民解放军陆军军医大学第一附属医院 | 用于胶质母细胞瘤治疗的药物组合物以及预后的诊断试剂 |
| CN116173048A (zh) * | 2023-01-19 | 2023-05-30 | 温州医科大学附属第一医院 | 棉子糖及其衍生物在胶质母细胞瘤治疗中的应用 |
| WO2025088835A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人大阪大学 | ヒト化抗ｃｋａｐ４抗体又はその抗原結合性断片 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| DK172541B1 (da) | 1982-10-08 | 1998-12-07 | Glaxo Group Ltd | Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet |
| DE3682457D1 (de) | 1985-07-30 | 1991-12-19 | Glaxo Group Ltd | Geraet zur verabreichung von medikamenten an patienten. |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| AU1700700A (en) | 1999-11-05 | 2001-05-14 | Forskarpatent I Syd Ab | Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis |
| EP2384763B1 (en) | 2005-05-30 | 2015-04-29 | Wntresearch AB | A peptide ligand to impair cancer cell migration |
| ES2527454T3 (es) * | 2008-08-13 | 2015-01-23 | Wntresearch Ab | El uso de derivados del péptido Wnt5-a para el tratamiento de melanoma y cáncer gástrico |
| CA2786745A1 (en) * | 2010-01-12 | 2011-07-21 | Oncomed Pharmaceuticals, Inc. | Wnt-binding agents and uses thereof |
| EP2446895A1 (en) | 2010-10-01 | 2012-05-02 | Stemgen S.P.A. | EPH receptor expression in tumor stem cells |
| DK2726880T3 (da) * | 2011-07-01 | 2019-07-15 | Wntresearch Ab | Behandling af prostatacancer og fremgangsmåde til bestemmelse af prognosen for prostatacancer |
| US20140171356A1 (en) | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| JP6921755B2 (ja) * | 2014-12-10 | 2021-08-18 | ハイパーステム ソシエテ アノニム | 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物 |
-
2015
- 2015-12-09 JP JP2017549860A patent/JP6921755B2/ja active Active
- 2015-12-09 CA CA2970140A patent/CA2970140A1/en active Pending
- 2015-12-09 US US15/533,842 patent/US10688167B2/en active Active
- 2015-12-09 DK DK15834638.7T patent/DK3229831T3/da active
- 2015-12-09 WO PCT/IB2015/002577 patent/WO2016092378A1/en not_active Ceased
- 2015-12-09 EP EP15834638.7A patent/EP3229831B1/en active Active
- 2015-12-09 AU AU2015359043A patent/AU2015359043C1/en active Active
- 2015-12-09 ES ES15834638T patent/ES2796973T3/es active Active
- 2015-12-09 KR KR1020177018938A patent/KR102674191B1/ko active Active
-
2020
- 2020-05-13 US US15/931,081 patent/US11357840B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015359043B2 (en) | 2021-09-02 |
| WO2016092378A1 (en) | 2016-06-16 |
| US10688167B2 (en) | 2020-06-23 |
| EP3229831A1 (en) | 2017-10-18 |
| EP3229831B1 (en) | 2020-03-11 |
| JP2018500390A (ja) | 2018-01-11 |
| NZ732532A (en) | 2024-10-25 |
| KR20170098861A (ko) | 2017-08-30 |
| KR102674191B1 (ko) | 2024-06-11 |
| US20170368158A1 (en) | 2017-12-28 |
| AU2015359043C1 (en) | 2022-01-06 |
| JP6921755B2 (ja) | 2021-08-18 |
| US11357840B2 (en) | 2022-06-14 |
| ES2796973T3 (es) | 2020-11-30 |
| AU2015359043A1 (en) | 2017-06-29 |
| CA2970140A1 (en) | 2016-06-16 |
| HK1245152A1 (en) | 2018-08-24 |
| US20200345821A1 (en) | 2020-11-05 |
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