JP2017536124A5 - - Google Patents
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- Publication number
- JP2017536124A5 JP2017536124A5 JP2017527259A JP2017527259A JP2017536124A5 JP 2017536124 A5 JP2017536124 A5 JP 2017536124A5 JP 2017527259 A JP2017527259 A JP 2017527259A JP 2017527259 A JP2017527259 A JP 2017527259A JP 2017536124 A5 JP2017536124 A5 JP 2017536124A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- purified mutant
- mutant pneumolysin
- pneumolysin polypeptide
- polypeptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462082848P | 2014-11-21 | 2014-11-21 | |
| US62/082,848 | 2014-11-21 | ||
| PCT/US2015/061859 WO2016081839A1 (en) | 2014-11-21 | 2015-11-20 | Pneumolysin mutants and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017536124A JP2017536124A (ja) | 2017-12-07 |
| JP2017536124A5 true JP2017536124A5 (https=) | 2018-12-27 |
| JP6734274B2 JP6734274B2 (ja) | 2020-08-05 |
Family
ID=56014598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527259A Expired - Fee Related JP6734274B2 (ja) | 2014-11-21 | 2015-11-20 | ニューモリシン突然変異体とその利用方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10562941B2 (https=) |
| EP (2) | EP4501949A3 (https=) |
| JP (1) | JP6734274B2 (https=) |
| KR (1) | KR102304828B1 (https=) |
| CN (1) | CN107106635B (https=) |
| AU (1) | AU2015349787B2 (https=) |
| DK (1) | DK3220937T3 (https=) |
| ES (1) | ES2993430T3 (https=) |
| FI (1) | FI3220937T3 (https=) |
| HR (1) | HRP20241627T1 (https=) |
| HU (1) | HUE069200T2 (https=) |
| LT (1) | LT3220937T (https=) |
| MX (1) | MX381872B (https=) |
| PL (1) | PL3220937T3 (https=) |
| PT (1) | PT3220937T (https=) |
| RS (1) | RS66221B1 (https=) |
| SI (1) | SI3220937T1 (https=) |
| SM (1) | SMT202400482T1 (https=) |
| WO (1) | WO2016081839A1 (https=) |
| ZA (1) | ZA201703881B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9181308B2 (en) | 2011-03-28 | 2015-11-10 | St. Jude Children's Research Hospital | Methods and compositions employing immunogenic fusion proteins |
| US11844829B2 (en) | 2016-12-28 | 2023-12-19 | Zalvac Ab | Microparticles from Streptococcus pneumoniae as vaccine antigens |
| CN110967482B (zh) * | 2018-09-30 | 2023-04-07 | 重庆市畜牧科学院 | 一种山羊化脓隐秘杆菌感染检测试剂盒及其检测方法 |
| CN113264999B (zh) * | 2021-04-29 | 2023-02-28 | 星济生物(苏州)有限公司 | 中和肺炎链球菌溶血素蛋白的抗原结合蛋白及其用途 |
| IL326005A (en) | 2021-09-09 | 2026-03-01 | Affinivax Inc | Multivalent pneumococcal vaccines |
| AU2022391752A1 (en) | 2021-11-18 | 2024-06-13 | Matrivax, Inc. | Immunogenic fusion protein compositions and methods of use thereof |
| CN115927420A (zh) * | 2022-05-27 | 2023-04-07 | 贵州省畜牧兽医研究所 | 一种溶血素重组表达及间接elisa检测方法及应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4686102A (en) | 1984-04-12 | 1987-08-11 | American Cyanamid Company | Multivalent pneumococcal vaccine and preparation thereof |
| US6716432B1 (en) | 1988-12-16 | 2004-04-06 | James Cleland Paton | Pneumolysin mutants and pneumococcal vaccines made therefrom |
| RU2121481C1 (ru) | 1988-12-16 | 1998-11-10 | Де Стат Дер Недерланден Вертегенвордигд Дор де Министр Ван Велзейн, Волксгезондхейд эн Кюлтюр | Модифицированный пневмолизин, рекомбинантная плазмида, способ получения модифицированного пневмолизина, вакцина |
| US5854416A (en) | 1991-11-14 | 1998-12-29 | The United States Of America As Represented By The Department Of Health And Human Services | Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor |
| US5565204A (en) | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| JPH11514844A (ja) | 1995-06-07 | 1999-12-21 | リージェンツ オブ ザ ユニバーシティー オブ ミネソタ | 連鎖球菌毒素ａの突然変異体および使用方法 |
| JP2001510031A (ja) | 1997-07-21 | 2001-07-31 | ノース・アメリカン・ヴァクシン・インコーポレーテッド | ワクチンとしての修飾された免疫原ニューモリシン組成物 |
| US6224880B1 (en) | 1997-09-24 | 2001-05-01 | Merck & Co., Inc. | Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines |
| US6903184B1 (en) | 1998-03-02 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Multiple antigenic peptides immunogenic against Streptococcus pneumonia |
| WO2000005378A2 (en) | 1998-07-22 | 2000-02-03 | Id-Lelystad Instituut Voor Dierhouderij En Diergezondheid B.V. | Streptococcus suis vaccines and diagnostic tests |
| ES2322306T3 (es) | 1998-12-21 | 2009-06-18 | Medimmune, Inc. | Proteinas de streptpcpccus pneumoniae y fragmentos inmunogenicos para vacunas. |
| US6887480B1 (en) | 1999-06-10 | 2005-05-03 | Medimmune, Inc. | Streptococcus pneumoniae proteins and vaccines |
| EP1456231A2 (en) | 2001-12-20 | 2004-09-15 | Shire Biochem Inc. | Streptococcus antigens |
| ES2451620T3 (es) | 2002-11-07 | 2014-03-28 | Synergy America, Inc. | Composiciones y métodos destinados a tratar o prevenir la infección neumocócica |
| WO2005076696A2 (en) | 2004-02-13 | 2005-08-25 | Sanofi Pasteur Limited | Pneumolysin derivatives |
| GB0410220D0 (en) | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
| WO2005108419A1 (en) | 2004-05-07 | 2005-11-17 | Lea-Ann Kirkham | Mutant cholesterol-binding cytolysin proteins |
| WO2007144647A2 (en) | 2006-06-15 | 2007-12-21 | Timothy John Mitchell | Adjuvant compositions |
| CA2683748C (en) * | 2007-04-13 | 2016-02-16 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
| CN102712680B (zh) * | 2008-12-24 | 2016-06-22 | 荷兰王国卫生福利和运动部国家公共卫生和环境研究所 | 修饰的肺炎链球菌溶血素(ply)多肽 |
| US9649372B2 (en) * | 2009-12-22 | 2017-05-16 | Sanofi Pasteur Limited | Immunogenic compositions and related methods |
| CL2010001216A1 (es) * | 2010-11-08 | 2011-01-28 | New Tech Copper S P A | Sistema para confinar el espacio sobre el electrolito en una celda de electro obtencion y evacuar los aerosoles generados, que comprende un confinador insertado en cada anodo, con un par de proyecciones flexibles y un par de perfiles en angulo, y ductos longitudinales con perforaciones sobre el nivel del electrolito. |
| US9181308B2 (en) | 2011-03-28 | 2015-11-10 | St. Jude Children's Research Hospital | Methods and compositions employing immunogenic fusion proteins |
| JP6397805B2 (ja) | 2015-08-28 | 2018-09-26 | 東芝メモリ株式会社 | 半導体製造装置およびその運転方法 |
-
2015
- 2015-11-20 AU AU2015349787A patent/AU2015349787B2/en active Active
- 2015-11-20 LT LTEPPCT/US2015/061859T patent/LT3220937T/lt unknown
- 2015-11-20 PT PT158617118T patent/PT3220937T/pt unknown
- 2015-11-20 KR KR1020177016881A patent/KR102304828B1/ko active Active
- 2015-11-20 HU HUE15861711A patent/HUE069200T2/hu unknown
- 2015-11-20 US US15/527,919 patent/US10562941B2/en active Active
- 2015-11-20 ES ES15861711T patent/ES2993430T3/es active Active
- 2015-11-20 MX MX2017006625A patent/MX381872B/es unknown
- 2015-11-20 EP EP24198287.5A patent/EP4501949A3/en not_active Withdrawn
- 2015-11-20 CN CN201580071394.2A patent/CN107106635B/zh active Active
- 2015-11-20 EP EP15861711.8A patent/EP3220937B1/en active Active
- 2015-11-20 HR HRP20241627TT patent/HRP20241627T1/hr unknown
- 2015-11-20 FI FIEP15861711.8T patent/FI3220937T3/fi active
- 2015-11-20 JP JP2017527259A patent/JP6734274B2/ja not_active Expired - Fee Related
- 2015-11-20 SI SI201532045T patent/SI3220937T1/sl unknown
- 2015-11-20 SM SM20240482T patent/SMT202400482T1/it unknown
- 2015-11-20 DK DK15861711.8T patent/DK3220937T3/da active
- 2015-11-20 RS RS20241316A patent/RS66221B1/sr unknown
- 2015-11-20 PL PL15861711.8T patent/PL3220937T3/pl unknown
- 2015-11-20 WO PCT/US2015/061859 patent/WO2016081839A1/en not_active Ceased
-
2017
- 2017-06-06 ZA ZA2017/03881A patent/ZA201703881B/en unknown
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