JP2017533710A5 - - Google Patents
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- JP2017533710A5 JP2017533710A5 JP2017524429A JP2017524429A JP2017533710A5 JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5 JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5
- Authority
- JP
- Japan
- Prior art keywords
- capture
- primer
- well
- layer
- primer pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108091033319 polynucleotide Proteins 0.000 claims 36
- 102000040430 polynucleotide Human genes 0.000 claims 36
- 239000002157 polynucleotide Substances 0.000 claims 36
- 239000000758 substrate Substances 0.000 claims 25
- 239000002773 nucleotide Substances 0.000 claims 20
- 125000003729 nucleotide group Chemical group 0.000 claims 20
- 238000000034 method Methods 0.000 claims 19
- 238000002493 microarray Methods 0.000 claims 13
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 230000000295 complement effect Effects 0.000 claims 11
- 108091093088 Amplicon Proteins 0.000 claims 10
- 239000011248 coating agent Substances 0.000 claims 9
- 238000000576 coating method Methods 0.000 claims 9
- 238000000151 deposition Methods 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 9
- 230000003321 amplification Effects 0.000 claims 3
- 238000003199 nucleic acid amplification method Methods 0.000 claims 3
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 claims 3
- -1 5-azidoacetamidylpentyl Chemical group 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000003190 augmentative effect Effects 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021213441A JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462078346P | 2014-11-11 | 2014-11-11 | |
| US62/078,346 | 2014-11-11 | ||
| US201462096464P | 2014-12-23 | 2014-12-23 | |
| US62/096,464 | 2014-12-23 | ||
| PCT/EP2015/076353 WO2016075204A1 (en) | 2014-11-11 | 2015-11-11 | Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Division JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533710A JP2017533710A (ja) | 2017-11-16 |
| JP2017533710A5 true JP2017533710A5 (https=) | 2018-12-20 |
| JP7032930B2 JP7032930B2 (ja) | 2022-03-09 |
Family
ID=54540094
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524429A Active JP7032930B2 (ja) | 2014-11-11 | 2015-11-11 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10619204B2 (https=) |
| EP (1) | EP3218511B1 (https=) |
| JP (2) | JP7032930B2 (https=) |
| KR (1) | KR102590448B1 (https=) |
| CN (1) | CN107208019B (https=) |
| AU (1) | AU2015345125B2 (https=) |
| DK (1) | DK3218511T3 (https=) |
| ES (1) | ES2802405T3 (https=) |
| MY (1) | MY182476A (https=) |
| PL (1) | PL3218511T3 (https=) |
| PT (1) | PT3218511T (https=) |
| SG (2) | SG10202004350TA (https=) |
| WO (1) | WO2016075204A1 (https=) |
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| AU2014296253A1 (en) | 2013-07-30 | 2016-02-04 | President And Fellows Of Harvard College | Quantitative DNA-based imaging and super-resolution imaging |
| US10415083B2 (en) | 2013-10-28 | 2019-09-17 | The Translational Genomics Research Institute | Long insert-based whole genome sequencing |
| DK3218511T3 (da) | 2014-11-11 | 2020-07-20 | Illumina Cambridge Ltd | Fremgangsmåder og arrays til frembringelse og sekventering af monoklonale klynger af nukleinsyre |
| US20180057873A1 (en) * | 2015-04-17 | 2018-03-01 | Centrillion Technology Holdings Corporation | Methods for performing spatial profiling of biological materials |
| US20180224461A1 (en) * | 2015-08-07 | 2018-08-09 | President And Fellows Of Harvard College | Super resolution imaging of protein-protein interactions |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| JP2017209051A (ja) * | 2016-05-25 | 2017-11-30 | 株式会社ニコン | 標的生体分子の検出方法、標的生体分子検出用基板、及び標的生体分子検出装置 |
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| WO2018218136A1 (en) * | 2017-05-25 | 2018-11-29 | Integrated Dna Technologies, Inc. | Reverse complement adapters for the mitigation of umi hopping |
| US11001885B2 (en) | 2017-06-13 | 2021-05-11 | Personal Genomics Taiwan, Inc. | Apparatus for single molecular sequencing and method of sequencing nucleic acid molecules |
| IL319255A (en) | 2017-08-07 | 2025-04-01 | Univ Johns Hopkins | Methods and materials for cancer assessment and treatment |
| CN107523640A (zh) * | 2017-10-12 | 2017-12-29 | 厦门燕旭安生物科技有限公司 | 一种ctDNA精准测序的扩增子文库构建方法 |
| IL271026B2 (en) * | 2017-12-21 | 2024-11-01 | Illumina Inc | Flow cells with hydrogel coating |
| JP2021525095A (ja) * | 2018-05-28 | 2021-09-24 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｄｎａ−ポア−ポリメラーゼ複合体の酵素的濃縮 |
| US11124829B2 (en) * | 2018-06-29 | 2021-09-21 | Illumina, Inc. | Flow cells |
| TWI730352B (zh) | 2018-08-06 | 2021-06-11 | 英商伊路米納劍橋有限公司 | 流體槽與定序系統及製備用於其之基板的方法 |
| US20200149095A1 (en) * | 2018-11-14 | 2020-05-14 | Element Biosciences, Inc. | Low binding supports for improved solid-phase dna hybridization and amplification |
| SG11202012762WA (en) | 2018-12-05 | 2021-01-28 | Illumina Cambridge Ltd | Methods and compositions for cluster generation by bridge amplification |
| WO2020126602A1 (en) | 2018-12-18 | 2020-06-25 | Illumina Cambridge Limited | Methods and compositions for paired end sequencing using a single surface primer |
| EP3899037B1 (en) * | 2018-12-19 | 2023-10-18 | Illumina, Inc. | Methods for improving polynucleotide cluster clonality priority |
| TWI873119B (zh) * | 2019-01-29 | 2025-02-21 | 美商伊路米納有限公司 | 流通槽及製備其之方法 |
| TWI857001B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 定序套組 |
| TWI857000B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 流體槽以及將複合物引入至流體槽之方法 |
| WO2020241829A1 (ja) | 2019-05-31 | 2020-12-03 | 日本電気株式会社 | 情報処理装置、情報処理方法及び情報処理プログラム |
| CN112654719A (zh) * | 2019-05-31 | 2021-04-13 | 伊鲁米纳公司 | 使用流动池进行信息存储和检索的系统和方法 |
| TW202120693A (zh) * | 2019-08-21 | 2021-06-01 | 美商伊路米納有限公司 | 偵測核苷酸之聚合酶併入的方法 |
| IL286668B1 (en) | 2019-12-16 | 2026-04-01 | Illumina Cambridge Ltd | Kits and flow cells |
| KR20220116388A (ko) * | 2019-12-20 | 2022-08-23 | 일루미나, 인코포레이티드 | 플로우 셀 |
| PH12021553295A1 (en) * | 2019-12-23 | 2022-08-01 | Illumina Cambridge Ltd | Nanoparticle with single site for template polynucleotide attachment |
| JP2023513606A (ja) | 2020-02-14 | 2023-03-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 核酸を評価するための方法および材料 |
| WO2021168097A1 (en) * | 2020-02-19 | 2021-08-26 | Genapsys, Inc. | Methods and systems for nucleic acid processing |
| MX2021015806A (es) * | 2020-02-26 | 2022-04-27 | Illumina Inc | Kits para genotipificacion. |
| AU2021230282A1 (en) * | 2020-03-03 | 2022-09-22 | Pacific Biosciences Of California, Inc. | Methods and compositions for sequencing double stranded nucleic acids |
| EP3969612B1 (en) * | 2020-03-09 | 2024-10-30 | Illumina, Inc. | Improvements in nucleic acid sequencing |
| KR20230035237A (ko) | 2020-05-12 | 2023-03-13 | 일루미나, 인코포레이티드 | 재조합 말단 데옥시뉴클레오티딜 트랜스퍼라제를 사용하여 변형된 염기를 갖는 핵산의 생성 |
| KR20230069047A (ko) * | 2020-09-14 | 2023-05-18 | 일루미나, 인코포레이티드 | 폴리뉴클레오티드를 증폭시키기 위한 조성물 및 방법 |
| CN115803112A (zh) * | 2020-09-29 | 2023-03-14 | 伊鲁米纳公司 | 用于制造流通池的方法 |
| AU2021352376A1 (en) * | 2020-09-29 | 2023-01-05 | Illumina, Inc. | Flow cells and methods for making the same |
| TW202232084A (zh) * | 2020-12-10 | 2022-08-16 | 美商伊路米納有限公司 | 影像感測器結構及相關方法 |
| US20220195516A1 (en) * | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| EP4263868A4 (en) * | 2021-03-12 | 2024-11-27 | Singular Genomics Systems, Inc. | NANONETWORKS AND METHODS OF USE THEREOF |
| US11884977B2 (en) | 2021-03-12 | 2024-01-30 | Singular Genomics Systems, Inc. | Nanoarrays and methods of use thereof |
| CN117222752A (zh) * | 2021-04-30 | 2023-12-12 | 伊鲁米纳剑桥有限公司 | 流通池和方法 |
| WO2022240764A1 (en) * | 2021-05-10 | 2022-11-17 | Pacific Biosciences Of California, Inc. | Single-molecule seeding and amplification on a surface |
| WO2024006625A1 (en) * | 2022-06-27 | 2024-01-04 | Somalogic Operating Co., Inc. | Monoclonal polony generation using nucleic acid supramolecular structures |
| US20240076722A1 (en) * | 2022-06-29 | 2024-03-07 | 10X Genomics, Inc. | Compositions and methods for oligonucleotide inversion on arrays |
| CN116024320A (zh) * | 2022-07-13 | 2023-04-28 | 上海翔琼生物技术有限公司 | 一种用于检测核酸的荧光定量pcr方法 |
| WO2024057089A1 (en) * | 2022-09-09 | 2024-03-21 | Todx Inc. | Device for parallel detection and quantification of nucleic acid based markers |
| US20240124916A1 (en) * | 2022-09-16 | 2024-04-18 | Illumina Cambridge Limited | Nanoparticle with polynucleotide binding site and method of making thereof |
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| US20250207193A1 (en) * | 2023-12-22 | 2025-06-26 | Illumina, Inc. | Reusable flow cells and methods of using them for nucleic acid sequencing |
| CN117778578B (zh) * | 2023-12-29 | 2024-10-15 | 深圳海普洛斯医学检验实验室 | 一种基于高通量测序检测目标基因甲基化程度的引物组合物及其应用 |
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-
2015
- 2015-11-11 DK DK15793823.4T patent/DK3218511T3/da active
- 2015-11-11 PT PT157938234T patent/PT3218511T/pt unknown
- 2015-11-11 EP EP15793823.4A patent/EP3218511B1/en active Active
- 2015-11-11 KR KR1020177015817A patent/KR102590448B1/ko active Active
- 2015-11-11 AU AU2015345125A patent/AU2015345125B2/en active Active
- 2015-11-11 WO PCT/EP2015/076353 patent/WO2016075204A1/en not_active Ceased
- 2015-11-11 CN CN201580072860.9A patent/CN107208019B/zh active Active
- 2015-11-11 SG SG10202004350TA patent/SG10202004350TA/en unknown
- 2015-11-11 ES ES15793823T patent/ES2802405T3/es active Active
- 2015-11-11 JP JP2017524429A patent/JP7032930B2/ja active Active
- 2015-11-11 MY MYPI2017000708A patent/MY182476A/en unknown
- 2015-11-11 SG SG11201703693UA patent/SG11201703693UA/en unknown
- 2015-11-11 US US15/525,892 patent/US10619204B2/en active Active
- 2015-11-11 PL PL15793823T patent/PL3218511T3/pl unknown
-
2020
- 2020-04-10 US US16/846,028 patent/US11692223B2/en active Active
-
2021
- 2021-12-27 JP JP2021213441A patent/JP7323598B2/ja active Active
-
2023
- 2023-05-18 US US18/320,122 patent/US12385092B2/en active Active
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