JP2017532321A5 - - Google Patents
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- Publication number
- JP2017532321A5 JP2017532321A5 JP2017516323A JP2017516323A JP2017532321A5 JP 2017532321 A5 JP2017532321 A5 JP 2017532321A5 JP 2017516323 A JP2017516323 A JP 2017516323A JP 2017516323 A JP2017516323 A JP 2017516323A JP 2017532321 A5 JP2017532321 A5 JP 2017532321A5
- Authority
- JP
- Japan
- Prior art keywords
- glucopyranosyl
- galactopyranosyl
- amino
- glucopyranoside
- pentanyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001720 carbohydrates Chemical class 0.000 claims description 18
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 5
- 241000193998 Streptococcus pneumoniae Species 0.000 claims description 4
- 150000004676 glycans Chemical class 0.000 claims description 4
- 229920001282 polysaccharide Polymers 0.000 claims description 4
- 239000005017 polysaccharide Substances 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims description 4
- -1 5-aminopentanyl Chemical group 0.000 claims 19
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 8
- 235000000346 sugar Nutrition 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical group CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 claims 3
- 150000008163 sugars Chemical class 0.000 claims 3
- 125000004042 4-aminobutyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H] 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 208000031729 Bacteremia Diseases 0.000 claims 1
- 206010006458 Bronchitis chronic Diseases 0.000 claims 1
- 206010009137 Chronic sinusitis Diseases 0.000 claims 1
- 206010010741 Conjunctivitis Diseases 0.000 claims 1
- 201000009906 Meningitis Diseases 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 230000009798 acute exacerbation Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 206010006451 bronchitis Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000007451 chronic bronchitis Diseases 0.000 claims 1
- 201000005547 chronic conjunctivitis Diseases 0.000 claims 1
- 208000027157 chronic rhinosinusitis Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 238000010324 immunological assay Methods 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010057249 Phagocytosis Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 1
- 230000008782 phagocytosis Effects 0.000 description 1
- 150000004044 tetrasaccharides Chemical class 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14186597.2A EP3000820A1 (en) | 2014-09-26 | 2014-09-26 | Synthetic vaccines against Streptococcus pneumoniae serotype 8 |
| EP14186597.2 | 2014-09-26 | ||
| EP15163290.8 | 2015-04-10 | ||
| EP15163290 | 2015-04-10 | ||
| PCT/EP2015/072294 WO2016046420A1 (en) | 2014-09-26 | 2015-09-28 | Vaccines against streptococcus pneumoniae serotype 8 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017532321A JP2017532321A (ja) | 2017-11-02 |
| JP2017532321A5 true JP2017532321A5 (enExample) | 2019-01-10 |
| JP6524218B2 JP6524218B2 (ja) | 2019-06-05 |
Family
ID=54196977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017516323A Active JP6524218B2 (ja) | 2014-09-26 | 2015-09-28 | 肺炎連鎖球菌血清型８に対するワクチン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10220083B2 (enExample) |
| EP (1) | EP3197907B1 (enExample) |
| JP (1) | JP6524218B2 (enExample) |
| KR (1) | KR102480429B1 (enExample) |
| CN (1) | CN106879257B (enExample) |
| AU (1) | AU2015323651B2 (enExample) |
| CA (1) | CA2961694C (enExample) |
| WO (1) | WO2016046420A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| US10188718B2 (en) * | 2014-12-12 | 2019-01-29 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Vaccines against Streptococcus pneumoniae serotype 4 |
| CN108367063A (zh) * | 2015-07-21 | 2018-08-03 | 辉瑞公司 | 包含缀合的荚膜糖抗原的免疫原性组合物及其试剂盒和用途 |
| MX371087B (es) * | 2015-12-17 | 2020-01-16 | Max Planck Gesellschaft | Vacunas sintéticas contra el serotipo 2 de streptococcus pneumoniae. |
| EP3269385A1 (en) * | 2016-07-12 | 2018-01-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Pneumococcal polysaccharide-protein conjugate composition |
| EP3474890A1 (en) | 2016-06-22 | 2019-05-01 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften E. V. | Pneumococcal polysaccharide-protein conjugate composition |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| EP3492481A1 (en) | 2017-11-30 | 2019-06-05 | Vaxxilon AG | Vaccine against klebsiella pneumoniae |
| CN108558961B (zh) * | 2018-01-29 | 2019-08-06 | 江南大学 | 类志贺邻单胞菌o51血清型o抗原寡糖化学合成方法 |
| WO2024102630A1 (en) * | 2022-11-07 | 2024-05-16 | The Uab Research Foundation | Pneumococcal and other vaccines potentiated with saponin adjuvant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL121585A0 (en) * | 1995-06-07 | 1998-02-08 | Alberta Res Council | Immunogenic and immunostimulatory oligosaccharide compositions and methods of preparing and using them |
| CN104873965B (zh) * | 2007-06-26 | 2018-09-11 | 葛兰素史密丝克莱恩生物有限公司 | 包含肺炎链球菌荚膜多糖缀合物的疫苗 |
| EP2788746B1 (en) | 2011-11-22 | 2018-10-24 | Stephen G. Haralampu | Stopped-flow, micro-fluidic device and method for the charge-based separation of complex analyte mixtures |
| WO2013178236A1 (en) * | 2012-05-26 | 2013-12-05 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. | Carbohydrate-glycolipid conjugate vaccines |
-
2015
- 2015-09-28 CA CA2961694A patent/CA2961694C/en active Active
- 2015-09-28 WO PCT/EP2015/072294 patent/WO2016046420A1/en not_active Ceased
- 2015-09-28 KR KR1020177008075A patent/KR102480429B1/ko active Active
- 2015-09-28 US US15/513,868 patent/US10220083B2/en active Active
- 2015-09-28 JP JP2017516323A patent/JP6524218B2/ja active Active
- 2015-09-28 EP EP15770548.4A patent/EP3197907B1/en active Active
- 2015-09-28 CN CN201580051613.0A patent/CN106879257B/zh active Active
- 2015-09-28 AU AU2015323651A patent/AU2015323651B2/en active Active
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