JP2017532291A5 - - Google Patents
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- JP2017532291A5 JP2017532291A5 JP2017505805A JP2017505805A JP2017532291A5 JP 2017532291 A5 JP2017532291 A5 JP 2017532291A5 JP 2017505805 A JP2017505805 A JP 2017505805A JP 2017505805 A JP2017505805 A JP 2017505805A JP 2017532291 A5 JP2017532291 A5 JP 2017532291A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery vehicle
- lipid
- vehicle according
- active ingredient
- lipophilic active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000002632 lipids Chemical class 0.000 claims description 11
- 230000004888 barrier function Effects 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 238000009792 diffusion process Methods 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims 20
- 239000004480 active ingredient Substances 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 9
- 239000011159 matrix material Substances 0.000 claims 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 229920001222 biopolymer Polymers 0.000 claims 4
- -1 konjac mannan Polymers 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 3
- 239000003995 emulsifying agent Substances 0.000 claims 3
- 235000013305 food Nutrition 0.000 claims 3
- 235000013376 functional food Nutrition 0.000 claims 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 239000004094 surface-active agent Substances 0.000 claims 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 2
- 229920002148 Gellan gum Polymers 0.000 claims 2
- 102000016943 Muramidase Human genes 0.000 claims 2
- 108010014251 Muramidase Proteins 0.000 claims 2
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims 2
- 108010084695 Pea Proteins Proteins 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 238000004132 cross linking Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 235000010335 lysozyme Nutrition 0.000 claims 2
- 229960000274 lysozyme Drugs 0.000 claims 2
- 239000004325 lysozyme Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000002417 nutraceutical Substances 0.000 claims 2
- 235000021436 nutraceutical agent Nutrition 0.000 claims 2
- 235000019702 pea protein Nutrition 0.000 claims 2
- CNVZJPUDSLNTQU-SEYXRHQNSA-N petroselinic acid Chemical compound CCCCCCCCCCC\C=C/CCCCC(O)=O CNVZJPUDSLNTQU-SEYXRHQNSA-N 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 229960003471 retinol Drugs 0.000 claims 2
- 235000020944 retinol Nutrition 0.000 claims 2
- 239000011607 retinol Substances 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- OXEDXHIBHVMDST-UHFFFAOYSA-N 12Z-octadecenoic acid Natural products CCCCCC=CCCCCCCCCCCC(O)=O OXEDXHIBHVMDST-UHFFFAOYSA-N 0.000 claims 1
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 claims 1
- 238000010146 3D printing Methods 0.000 claims 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 229920001817 Agar Polymers 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 claims 1
- 235000006008 Brassica napus var napus Nutrition 0.000 claims 1
- 240000000385 Brassica napus var. napus Species 0.000 claims 1
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 claims 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 claims 1
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 102000002322 Egg Proteins Human genes 0.000 claims 1
- 108010000912 Egg Proteins Proteins 0.000 claims 1
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 108010068370 Glutens Proteins 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 102000010445 Lactoferrin Human genes 0.000 claims 1
- 108010063045 Lactoferrin Proteins 0.000 claims 1
- 102000008192 Lactoglobulins Human genes 0.000 claims 1
- 108010060630 Lactoglobulins Proteins 0.000 claims 1
- 229920000161 Locust bean gum Polymers 0.000 claims 1
- 241000219745 Lupinus Species 0.000 claims 1
- 208000019022 Mood disease Diseases 0.000 claims 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 206010033307 Overweight Diseases 0.000 claims 1
- 101710091688 Patatin Proteins 0.000 claims 1
- CNVZJPUDSLNTQU-UHFFFAOYSA-N Petroselaidic acid Natural products CCCCCCCCCCCC=CCCCCC(O)=O CNVZJPUDSLNTQU-UHFFFAOYSA-N 0.000 claims 1
- 108010073771 Soybean Proteins Proteins 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 102000007544 Whey Proteins Human genes 0.000 claims 1
- 108010046377 Whey Proteins Proteins 0.000 claims 1
- 229920002494 Zein Polymers 0.000 claims 1
- 108010055615 Zein Proteins 0.000 claims 1
- 239000008272 agar Substances 0.000 claims 1
- 229940023476 agar Drugs 0.000 claims 1
- 235000010419 agar Nutrition 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 1
- 230000036760 body temperature Effects 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 235000021466 carotenoid Nutrition 0.000 claims 1
- 150000001747 carotenoids Chemical class 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 229940113118 carrageenan Drugs 0.000 claims 1
- 229940106189 ceramide Drugs 0.000 claims 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 150000001840 cholesterol esters Chemical class 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 235000021323 fish oil Nutrition 0.000 claims 1
- 235000012041 food component Nutrition 0.000 claims 1
- 239000005417 food ingredient Substances 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 229940014259 gelatin Drugs 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 235000010492 gellan gum Nutrition 0.000 claims 1
- 239000000216 gellan gum Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000002563 ionic surfactant Substances 0.000 claims 1
- 229940025902 konjac mannan Drugs 0.000 claims 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 claims 1
- 229940078795 lactoferrin Drugs 0.000 claims 1
- 235000021242 lactoferrin Nutrition 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 235000010420 locust bean gum Nutrition 0.000 claims 1
- 239000000711 locust bean gum Substances 0.000 claims 1
- 239000000155 melt Substances 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229960000292 pectin Drugs 0.000 claims 1
- 238000010419 pet care Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 229940075999 phytosterol ester Drugs 0.000 claims 1
- 150000008442 polyphenolic compounds Chemical class 0.000 claims 1
- 235000013824 polyphenols Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 229940001941 soy protein Drugs 0.000 claims 1
- 150000003408 sphingolipids Chemical class 0.000 claims 1
- 229940126672 traditional medicines Drugs 0.000 claims 1
- AQWHMKSIVLSRNY-UHFFFAOYSA-N trans-Octadec-5-ensaeure Natural products CCCCCCCCCCCCC=CCCCC(O)=O AQWHMKSIVLSRNY-UHFFFAOYSA-N 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- 235000021119 whey protein Nutrition 0.000 claims 1
- 239000005019 zein Substances 0.000 claims 1
- 229940093612 zein Drugs 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14180139 | 2014-08-07 | ||
| EP14180139.9 | 2014-08-07 | ||
| PCT/EP2015/067123 WO2016020217A1 (en) | 2014-08-07 | 2015-07-27 | A delivery system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017532291A JP2017532291A (ja) | 2017-11-02 |
| JP2017532291A5 true JP2017532291A5 (https=) | 2019-06-27 |
| JP6660372B2 JP6660372B2 (ja) | 2020-03-11 |
Family
ID=51302903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017505805A Expired - Fee Related JP6660372B2 (ja) | 2014-08-07 | 2015-07-27 | 送達システム |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10052287B2 (https=) |
| EP (1) | EP3177274A1 (https=) |
| JP (1) | JP6660372B2 (https=) |
| CN (1) | CN106572979B (https=) |
| WO (1) | WO2016020217A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011239414A1 (en) | 2010-04-15 | 2012-11-08 | The Washington University | Prodrug compositions, prodrug nanoparticles, and methods of use thereof |
| CN107019797B (zh) * | 2016-01-30 | 2020-07-03 | 天津赫莱恩特生物科技有限公司 | 一种提高球虫卵囊穿透细胞能力的组合物及其制备方法 |
| FR3054104B1 (fr) * | 2016-07-19 | 2018-08-31 | Galewpet | Support pour l’absorption orale d’une substance active par des animaux, son procede de preparation et ses utilisations |
| WO2019066442A2 (ko) * | 2017-09-27 | 2019-04-04 | 한양대학교 산학협력단 | 제2형 당뇨병 치료를 위한 락토페린 기반의 유전자 전달체 |
| KR102144380B1 (ko) | 2017-09-27 | 2020-08-13 | 한양대학교 산학협력단 | 제2형 당뇨병 치료를 위한 락토페린 기반의 유전자 전달체 |
| JP7004968B2 (ja) * | 2017-10-06 | 2022-01-21 | 青葉化成株式会社 | 食用の徐放性機能材の製造方法 |
| KR102790067B1 (ko) | 2017-11-03 | 2025-04-04 | 디에스엠 아이피 어셋츠 비.브이. | 신규한 전달 체계 |
| GB2571749A (en) * | 2018-03-07 | 2019-09-11 | Anabio Tech Limited | A method inducing satiety in a mammal |
| CN110353271B (zh) * | 2019-06-13 | 2022-07-22 | 陕西科技大学 | 一种抑制食道反流的特殊医学食品增稠组件及其制备方法 |
| FR3102913B1 (fr) * | 2019-11-07 | 2024-08-02 | Huddle Corp | Aliment ou complément alimentaire pour animaux d’élevage |
| US20220225650A1 (en) | 2021-01-21 | 2022-07-21 | Tropicana Products, Inc. | Materials and Methods for Inhibiting Material Mixing in a Material Processing System |
| CN113368130B (zh) * | 2021-06-25 | 2023-02-28 | 陕西科技大学 | 一种纤维状载铁复合物及其制备方法 |
| US11590071B2 (en) | 2021-07-06 | 2023-02-28 | King Abdulaziz University | Injectable drug delivery implant composition and method of use thereof |
| CN116999404B (zh) * | 2023-06-21 | 2025-11-21 | 西南大学 | 一种分隔化多腔室铁蛋白递送体系的制备方法与应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6115733A (ja) * | 1984-06-30 | 1986-01-23 | Miyoshi Oil & Fat Co Ltd | マイクロカプセルの製造方法 |
| DE19856432A1 (de) * | 1998-12-08 | 2000-06-15 | Basf Ag | Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen |
| JP2001342127A (ja) * | 2000-06-02 | 2001-12-11 | Nomoto Kikuo | 腸吸収性抗炎症因子含有免疫性物質及びその応用 |
| JP4833553B2 (ja) * | 2002-11-04 | 2011-12-07 | オーシャン・ニュートリション・カナダ・リミテッド | 複数の殻を有するマイクロカプセル及びそれらの調製方法 |
| JP2006510359A (ja) * | 2002-12-18 | 2006-03-30 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 親油性コアを含む複合コアセルベートカプセル |
| ZA200508355B (en) * | 2003-05-28 | 2007-03-28 | Unilever Plc | Satiety enhancing food products |
| KR20080055788A (ko) * | 2005-07-07 | 2008-06-19 | 오션 뉴트리션 캐나다 리미티드 | 이송 장치가 구비된 식품 및 이의 제조를 위한 방법 |
| ES2604081T3 (es) | 2007-01-10 | 2017-03-02 | Dsm Nutritional Products Ag | Microcápsulas que incluyen proteína de guisante |
| US9332774B2 (en) * | 2007-06-27 | 2016-05-10 | Bunge Oils, Inc. | Microencapsulated oil product and method of making same |
| US9186640B2 (en) * | 2007-08-28 | 2015-11-17 | Pepsico, Inc. | Delivery and controlled release of encapsulated lipophilic nutrients |
| GB0811024D0 (en) * | 2008-06-17 | 2008-07-23 | E Therapeutics Plc | Sustained release treatment of depression |
| BRPI1001091A2 (pt) * | 2009-04-22 | 2011-03-22 | Dr Suwelack Skin & Health Care Ag | artigo moldado revestido secado por congelamento |
| US20110150995A1 (en) * | 2009-12-22 | 2011-06-23 | Hemant Narahar Joshi | Solid Dosage Forms of Essential Oils |
| EP2625966A1 (en) * | 2012-02-13 | 2013-08-14 | Bionanoplus, S.L. | Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof |
| CN103301091B (zh) * | 2012-03-12 | 2014-12-03 | 昆明制药集团股份有限公司 | 一种天麻素两次脉冲释药制剂 |
| CL2012002056A1 (es) * | 2012-07-24 | 2014-01-24 | Map Chile SpA | Proteina animal micrencapsulada para consumo humano que comprende particulas proteicas, y una matriz de gelatina de origen animal; y particula de proteina animal microencapsulada para consumo humano. |
| US10075858B2 (en) * | 2012-09-20 | 2018-09-11 | Telefonaktiebolaget L M Ericsson (Publ) | Weighted RSRP measurement |
| WO2014078912A1 (en) * | 2012-11-26 | 2014-05-30 | Progel Pty Ltd | Coating composition |
-
2015
- 2015-07-27 WO PCT/EP2015/067123 patent/WO2016020217A1/en not_active Ceased
- 2015-07-27 CN CN201580041052.6A patent/CN106572979B/zh not_active Expired - Fee Related
- 2015-07-27 JP JP2017505805A patent/JP6660372B2/ja not_active Expired - Fee Related
- 2015-07-27 EP EP15741566.2A patent/EP3177274A1/en not_active Withdrawn
- 2015-07-27 US US15/502,007 patent/US10052287B2/en active Active
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2018
- 2018-07-25 US US16/045,287 patent/US10646450B2/en not_active Expired - Fee Related
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