JP2017530127A - 心室性不整脈の予防、治療、又は遅延におけるニューレグリンの使用、及びその組成物 - Google Patents

心室性不整脈の予防、治療、又は遅延におけるニューレグリンの使用、及びその組成物 Download PDF

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JP2017530127A
JP2017530127A JP2017516166A JP2017516166A JP2017530127A JP 2017530127 A JP2017530127 A JP 2017530127A JP 2017516166 A JP2017516166 A JP 2017516166A JP 2017516166 A JP2017516166 A JP 2017516166A JP 2017530127 A JP2017530127 A JP 2017530127A
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ventricular
nrg
arrhythmia
neuregulin
treating
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JP2017530127A5 (enExample
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ズホウ ミングドング
ズホウ ミングドング
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ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．
ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．
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Application filed by ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．, ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． filed Critical ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
JP2017516166A 2014-09-24 2015-09-06 心室性不整脈の予防、治療、又は遅延におけるニューレグリンの使用、及びその組成物 Pending JP2017530127A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410529437.4 2014-09-24
CN201410529437.4A CN105497876B (zh) 2014-09-24 2014-09-24 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物
PCT/CN2015/088972 WO2016045493A1 (zh) 2014-09-24 2015-09-06 神经调节蛋白预防、治疗或延迟室性心律失常的用途及其组合物

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JP2017530127A true JP2017530127A (ja) 2017-10-12
JP2017530127A5 JP2017530127A5 (enExample) 2018-09-27

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JP2017516166A Pending JP2017530127A (ja) 2014-09-24 2015-09-06 心室性不整脈の予防、治療、又は遅延におけるニューレグリンの使用、及びその組成物

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US (1) US10441633B2 (enExample)
EP (1) EP3199174B1 (enExample)
JP (1) JP2017530127A (enExample)
KR (1) KR20170055492A (enExample)
CN (2) CN105497876B (enExample)
AU (1) AU2015320230B2 (enExample)
CA (1) CA2961813A1 (enExample)
RU (1) RU2017113775A (enExample)
WO (1) WO2016045493A1 (enExample)

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BRPI0620819A2 (pt) 2005-12-30 2011-11-22 Zensun Shangai Science & Technology Ltd uso de uma neuregulina (nrg) de liberação prolongada, nrg em uma liberação prolongada de uma dosagem baixa constante, e, composição de liberação prolongada para prevenir, tratar ou retardar uma doença ou distúrbio em um mamìfero
JP6096262B2 (ja) 2009-08-25 2017-03-15 ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． ニューレグリンに基づく心不全の治療方法
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
JP6475623B2 (ja) 2012-10-08 2019-02-27 ゼンスン（シャンハイ）サイエンス アンド テクノロジー カンパニー リミテッド 糖尿病患者における心不全の治療用組成物
CA2911848A1 (en) 2013-05-22 2014-11-27 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for treating heart failure
CN110946993A (zh) 2014-01-03 2020-04-03 上海泽生科技开发股份有限公司 纽兰格林制剂的配方
CN105561298A (zh) 2014-10-17 2016-05-11 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
WO2020037076A1 (en) * 2018-08-14 2020-02-20 Emory University Inducing proliferation of cardiomyocytes and therapeutic uses related thereto
AR121035A1 (es) 2019-04-01 2022-04-13 Lilly Co Eli Compuestos de neuregulina-4 y métodos de uso
JP2022547335A (ja) * 2019-09-16 2022-11-11 ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． 組換えヒトニューレグリン誘導体及びその使用

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CN1498656A (zh) * 2002-11-08 2004-05-26 上海泽生科技开发有限公司 神经调节蛋白用于心肌梗死治疗的方法和组合物
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BRPI0620819A2 (pt) 2005-12-30 2011-11-22 Zensun Shangai Science & Technology Ltd uso de uma neuregulina (nrg) de liberação prolongada, nrg em uma liberação prolongada de uma dosagem baixa constante, e, composição de liberação prolongada para prevenir, tratar ou retardar uma doença ou distúrbio em um mamìfero
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Publication number Publication date
AU2015320230A1 (en) 2017-03-30
CN105497876A (zh) 2016-04-20
EP3199174A1 (en) 2017-08-02
WO2016045493A1 (zh) 2016-03-31
CA2961813A1 (en) 2016-03-31
US10441633B2 (en) 2019-10-15
EP3199174B1 (en) 2022-04-13
RU2017113775A (ru) 2018-10-26
EP3199174A4 (en) 2018-06-06
CN110337304A (zh) 2019-10-15
AU2015320230B2 (en) 2021-06-24
US20170368140A1 (en) 2017-12-28
RU2017113775A3 (enExample) 2019-04-04
KR20170055492A (ko) 2017-05-19
CN105497876B (zh) 2021-01-15

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